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The map label for this gene is minD [H]

Identifier: 18311120

GI number: 18311120

Start: 2448379

End: 2449176

Strand: Reverse

Name: minD [H]

Synonym: CPE2138

Alternate gene names: 18311120

Gene position: 2449176-2448379 (Counterclockwise)

Preceding gene: 18311121

Following gene: 18311119

Centisome position: 80.79

GC content: 31.33

Gene sequence:

>798_bases
ATGGGAGTATCGATAGTAATAACATCAGGAAAAGGTGGAGTTGGAAAAACAACTACTACAGCTAACATTGGAACAGCTTT
AGCGGCACAAGGAAAAAAGGTAGTCGTTGTTGATGGAGATACAGGTCTAAGAAACTTAGATGTGTTAATGGGATTAGAAA
ATAGAATTGTTTATACAGTAATTGATGTAATTGAAAATAGATGTAGAACTAAACAAGCTTTAATAAGAGATAAGAGATTT
AATAATTTATACTTATTACCTACTGCTCAAACTAAGGATAAAAATGATATAAGTCCTGAGCAAATGTTAAGATTAGTAAA
TGAATTAAAAGAAGAGTTTGATTATGTAATTTTAGATTGCCCAGCTGGTATAGAGCAAGGATTTGAAAATGCCATAGTTG
GGGCAGATAGAGCTATCGTAGTAGTTAATCCAGAAATAACTTCTGTAAGAGATGCTGATAGAGTTATTGGAAAACTTGAT
GCTAAGGGATTAGAAAATCATGAGGTTATAGTAAATAGATTAAATTATGAAATGACTAAAAAAGGTGATATGCTAGACAT
TTCAGATATTATAGAAACTCTTTCTGTAAAACTTTTAGGCGTTGTTCCAGATGATAGAAACATAACAGTTTCTACTAATA
AAGGAGAGCCTATAGTACTAGATGAAAAAGCAAGTGCAGGACAAGCATTTAGAAATATAGGTAGAAGAATAATAGGAGAA
GATGTTCCAATAATGGATTTAAACACAGAACATCAAGGAATATTTAGTTCTATATTAAAGTTGTTTAGAAGAGGGTAG

Upstream 100 bases:

>100_bases
CCGGAGGTGGCTAGATTGAATGAAAATAATATAATTGTAGAGCCTTATTTACCGGATAAATATTCTTATTAATATTACAT
AATTTAATGGAGGGAAAGTA

Downstream 100 bases:

>100_bases
GTGAGAGAAAATGAGTTTTTTAAATGTTTTTTCTAGTAGACCTACGCCGAAACAAGTTGCTAAGGATAGATTAAAGGTTA
TTTTAATCCATGATAGAGGG

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MGVSIVITSGKGGVGKTTTTANIGTALAAQGKKVVVVDGDTGLRNLDVLMGLENRIVYTVIDVIENRCRTKQALIRDKRF
NNLYLLPTAQTKDKNDISPEQMLRLVNELKEEFDYVILDCPAGIEQGFENAIVGADRAIVVVNPEITSVRDADRVIGKLD
AKGLENHEVIVNRLNYEMTKKGDMLDISDIIETLSVKLLGVVPDDRNITVSTNKGEPIVLDEKASAGQAFRNIGRRIIGE
DVPIMDLNTEHQGIFSSILKLFRRG

Sequences:

>Translated_265_residues
MGVSIVITSGKGGVGKTTTTANIGTALAAQGKKVVVVDGDTGLRNLDVLMGLENRIVYTVIDVIENRCRTKQALIRDKRF
NNLYLLPTAQTKDKNDISPEQMLRLVNELKEEFDYVILDCPAGIEQGFENAIVGADRAIVVVNPEITSVRDADRVIGKLD
AKGLENHEVIVNRLNYEMTKKGDMLDISDIIETLSVKLLGVVPDDRNITVSTNKGEPIVLDEKASAGQAFRNIGRRIIGE
DVPIMDLNTEHQGIFSSILKLFRRG
>Mature_264_residues
GVSIVITSGKGGVGKTTTTANIGTALAAQGKKVVVVDGDTGLRNLDVLMGLENRIVYTVIDVIENRCRTKQALIRDKRFN
NLYLLPTAQTKDKNDISPEQMLRLVNELKEEFDYVILDCPAGIEQGFENAIVGADRAIVVVNPEITSVRDADRVIGKLDA
KGLENHEVIVNRLNYEMTKKGDMLDISDIIETLSVKLLGVVPDDRNITVSTNKGEPIVLDEKASAGQAFRNIGRRIIGED
VPIMDLNTEHQGIFSSILKLFRRG

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=268, Percent_Identity=44.0298507462687, Blast_Score=236, Evalue=2e-63,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29087; Mature: 28956

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVSIVITSGKGGVGKTTTTANIGTALAAQGKKVVVVDGDTGLRNLDVLMGLENRIVYTV
CCEEEEEECCCCCCCCCEEECCCCHHHHCCCCEEEEEECCCCCCHHHHHHCCCCHHHHHH
IDVIENRCRTKQALIRDKRFNNLYLLPTAQTKDKNDISPEQMLRLVNELKEEFDYVILDC
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEC
PAGIEQGFENAIVGADRAIVVVNPEITSVRDADRVIGKLDAKGLENHEVIVNRLNYEMTK
CCHHHHCHHHHEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCEECC
KGDMLDISDIIETLSVKLLGVVPDDRNITVSTNKGEPIVLDEKASAGQAFRNIGRRIIGE
CCCEECHHHHHHHHCEEEEEECCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCC
DVPIMDLNTEHQGIFSSILKLFRRG
CCCEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GVSIVITSGKGGVGKTTTTANIGTALAAQGKKVVVVDGDTGLRNLDVLMGLENRIVYTV
CEEEEEECCCCCCCCCEEECCCCHHHHCCCCEEEEEECCCCCCHHHHHHCCCCHHHHHH
IDVIENRCRTKQALIRDKRFNNLYLLPTAQTKDKNDISPEQMLRLVNELKEEFDYVILDC
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEC
PAGIEQGFENAIVGADRAIVVVNPEITSVRDADRVIGKLDAKGLENHEVIVNRLNYEMTK
CCHHHHCHHHHEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCEECC
KGDMLDISDIIETLSVKLLGVVPDDRNITVSTNKGEPIVLDEKASAGQAFRNIGRRIIGE
CCCEECHHHHHHHHCEEEEEECCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCC
DVPIMDLNTEHQGIFSSILKLFRRG
CCCEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 8459776; 1400224; 9384377 [H]