Click here to switch to the map view.

The map label for this gene is rng [H]

Identifier: 18311113

GI number: 18311113

Start: 2440852

End: 2442294

Strand: Reverse

Name: rng [H]

Synonym: CPE2131

Alternate gene names: 18311113

Gene position: 2442294-2440852 (Counterclockwise)

Preceding gene: 18311114

Following gene: 18311112

Centisome position: 80.57

GC content: 26.61

Gene sequence:

>1443_bases
ATGAGAGATATATACGTAGAAAGAAGAGAAAATTTATTAAGGGTTGCCATAAAGAAAAATAATCTTTTAAGTGAGTGCTA
TATAGAAGAAGAGAGTCTAGAACCTGTTCAAGGAGAGATATATAAAGGTATAGTGAAAAGAGTAGTTCCAGGAATAAAGA
GTGCCTTTATAGATATTGGGTATAGTAAACAGGCCTATATGATACTTGGAGAAGATGAGAAAGATCTTAAACAAGGAGAT
GGAATAATCGTTGAAGTATTAAAAGAGCAATTTGGAAGTAAAGGGGCAAAAGTTACTTCAAAAATATCTTTAGCAGGAAG
ATATTGCGTCTTAGAAACTTCAAGAAATGATATTTCAATTTCAAGAAAGATAGAAAATCTAGAGTTTAAAAAAGAACTTG
AAAATTCATTGATAAAACCAAGTGAATTAGGGGTTACTGTTAGGACAAAAGCCCAATCAGCTAGTATTTTTGAGATTCAA
GAAGAAATAGAAGAACTATATAGAAACTATAAAGAGGTTATTAGAGAAGGTAAATTCTCCTTAAATCCAAAAAGATTATT
GGGTAAAGGAGACCTTATTAATAAGATAATTAGAGATGACATTGATGCTTATACTTCTTCAATAATTGTTGATTCTATAG
AAGATTACGAAAGAATAAAAGATAGTATTTCTAATTCTGAATATCTAAAAGTAATTCTTTATGATGATGCTAGAAGTCTT
TTTGATTATTATGGTATCGAAAAAGAAATTCTTAGCCTTAGAAATAATAGAGTTAATTTAAATTGTGGCGGAGACATAGT
TATAGAAAAAACAGAGGCTATGTATGTTATAGATGTTAATTCAGGTAAGAATACAAATCATAAAAATAAAGAAAAAACTG
CCTATGAAACTAATAAAAATGCGGCAATAGAAATTGCTAGACAAATTAAAATTAGAAATTTAGGTGGAATAATATTAGTT
GATTTTATAGATATGTATTCACAGGAAAACAAGAAAAAAATATTAAAAATATTAAAAGATGAATTTAAAAGTGATAGCCA
AAGAGCTAAAATTTTTCCTTTTACAGAGCTTGGATTAGTACAAATAACAAGATATAGAAAAGGAAAAAGCATTTATGAAT
ATATAGAAGAAAATTGCTTAGCATGCAATGGTCATGGAAAGAGATTAAAGTTATCTTATATAAATCTTCTTTTAAGAAAT
GAGATTTTGAAGAAAAATGGAGAAGGAAAGATAAAAGATTTCCATATAGAAATAAACTCTATTTATGAAAAAGATATTAG
AGGAAATATTTTTGAGTTTTTAAAAGAAATTGGAGCATTAGATTTAAATATTTACTTGAATTTTCAAGAATCTAAAGACT
TTTATAAAGTAGAACCATTGATCTTTAAAAATCAAATAGAAAGCGTAAAAGAGTATTTGGTGAAGAATATCGAAAAATAT
TAA

Upstream 100 bases:

>100_bases
GAAGAAGCTTTCGTAGAAATAAAAAGAGTTGAGATGTATGCATACAAAGGGAATACATTAGTTCCTCTATATAAATACAT
CTAAATTAGGAAGTGAATTC

Downstream 100 bases:

>100_bases
ATTTAGCTTTACAAAAGGCTTTAGCTATGATAGAATGGCTTTTGTAAACCGCTCACGAATAGGTTTTAAAAATAACTTTA
ATTAGTTTACCTTAAGTGGC

Product: ribonuclease, Rne/Rng family

Products: NA

Alternate protein names: RNase E [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MRDIYVERRENLLRVAIKKNNLLSECYIEEESLEPVQGEIYKGIVKRVVPGIKSAFIDIGYSKQAYMILGEDEKDLKQGD
GIIVEVLKEQFGSKGAKVTSKISLAGRYCVLETSRNDISISRKIENLEFKKELENSLIKPSELGVTVRTKAQSASIFEIQ
EEIEELYRNYKEVIREGKFSLNPKRLLGKGDLINKIIRDDIDAYTSSIIVDSIEDYERIKDSISNSEYLKVILYDDARSL
FDYYGIEKEILSLRNNRVNLNCGGDIVIEKTEAMYVIDVNSGKNTNHKNKEKTAYETNKNAAIEIARQIKIRNLGGIILV
DFIDMYSQENKKKILKILKDEFKSDSQRAKIFPFTELGLVQITRYRKGKSIYEYIEENCLACNGHGKRLKLSYINLLLRN
EILKKNGEGKIKDFHIEINSIYEKDIRGNIFEFLKEIGALDLNIYLNFQESKDFYKVEPLIFKNQIESVKEYLVKNIEKY

Sequences:

>Translated_480_residues
MRDIYVERRENLLRVAIKKNNLLSECYIEEESLEPVQGEIYKGIVKRVVPGIKSAFIDIGYSKQAYMILGEDEKDLKQGD
GIIVEVLKEQFGSKGAKVTSKISLAGRYCVLETSRNDISISRKIENLEFKKELENSLIKPSELGVTVRTKAQSASIFEIQ
EEIEELYRNYKEVIREGKFSLNPKRLLGKGDLINKIIRDDIDAYTSSIIVDSIEDYERIKDSISNSEYLKVILYDDARSL
FDYYGIEKEILSLRNNRVNLNCGGDIVIEKTEAMYVIDVNSGKNTNHKNKEKTAYETNKNAAIEIARQIKIRNLGGIILV
DFIDMYSQENKKKILKILKDEFKSDSQRAKIFPFTELGLVQITRYRKGKSIYEYIEENCLACNGHGKRLKLSYINLLLRN
EILKKNGEGKIKDFHIEINSIYEKDIRGNIFEFLKEIGALDLNIYLNFQESKDFYKVEPLIFKNQIESVKEYLVKNIEKY
>Mature_480_residues
MRDIYVERRENLLRVAIKKNNLLSECYIEEESLEPVQGEIYKGIVKRVVPGIKSAFIDIGYSKQAYMILGEDEKDLKQGD
GIIVEVLKEQFGSKGAKVTSKISLAGRYCVLETSRNDISISRKIENLEFKKELENSLIKPSELGVTVRTKAQSASIFEIQ
EEIEELYRNYKEVIREGKFSLNPKRLLGKGDLINKIIRDDIDAYTSSIIVDSIEDYERIKDSISNSEYLKVILYDDARSL
FDYYGIEKEILSLRNNRVNLNCGGDIVIEKTEAMYVIDVNSGKNTNHKNKEKTAYETNKNAAIEIARQIKIRNLGGIILV
DFIDMYSQENKKKILKILKDEFKSDSQRAKIFPFTELGLVQITRYRKGKSIYEYIEENCLACNGHGKRLKLSYINLLLRN
EILKKNGEGKIKDFHIEINSIYEKDIRGNIFEFLKEIGALDLNIYLNFQESKDFYKVEPLIFKNQIESVKEYLVKNIEKY

Specific function: Involved In The Processing Of The 5'End Of 16s Rrna. Could Be Involved In Chromosome Segregation And Cell Division. It May Be One Of The Components Of The Cytoplasmic Axial Filaments Bundles Or Merely Regulate The Formation Of This Structure. [C]

COG id: COG1530

COG function: function code J; Ribonucleases G and E

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI87082235, Length=400, Percent_Identity=32.5, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1787325, Length=424, Percent_Identity=31.3679245283019, Blast_Score=184, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR019307
- InterPro:   IPR022967
- InterPro:   IPR004659 [H]

Pfam domain/function: PF10150 RNase_E_G; PF00575 S1 [H]

EC number: =3.1.26.12 [H]

Molecular weight: Translated: 55580; Mature: 55580

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS50126 S1 ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDIYVERRENLLRVAIKKNNLLSECYIEEESLEPVQGEIYKGIVKRVVPGIKSAFIDIG
CCCCHHHHHCCCEEEEECCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHCCHHHHHEECC
YSKQAYMILGEDEKDLKQGDGIIVEVLKEQFGSKGAKVTSKISLAGRYCVLETSRNDISI
CCCCEEEEECCCHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCCCEEH
SRKIENLEFKKELENSLIKPSELGVTVRTKAQSASIFEIQEEIEELYRNYKEVIREGKFS
HHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
LNPKRLLGKGDLINKIIRDDIDAYTSSIIVDSIEDYERIKDSISNSEYLKVILYDDARSL
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHH
FDYYGIEKEILSLRNNRVNLNCGGDIVIEKTEAMYVIDVNSGKNTNHKNKEKTAYETNKN
HHHHCCHHHHHHHCCCEEEEECCCCEEEEECCEEEEEECCCCCCCCCCCCCHHHHHCCCC
AAIEIARQIKIRNLGGIILVDFIDMYSQENKKKILKILKDEFKSDSQRAKIFPFTELGLV
HHHHHHHHHEEECCCCEEEHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEECCCHHCCHH
QITRYRKGKSIYEYIEENCLACNGHGKRLKLSYINLLLRNEILKKNGEGKIKDFHIEINS
HHHHHHCCCHHHHHHHCCCEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEEEEEHH
IYEKDIRGNIFEFLKEIGALDLNIYLNFQESKDFYKVEPLIFKNQIESVKEYLVKNIEKY
HHHHHCCCHHHHHHHHHCCEEEEEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRDIYVERRENLLRVAIKKNNLLSECYIEEESLEPVQGEIYKGIVKRVVPGIKSAFIDIG
CCCCHHHHHCCCEEEEECCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHCCHHHHHEECC
YSKQAYMILGEDEKDLKQGDGIIVEVLKEQFGSKGAKVTSKISLAGRYCVLETSRNDISI
CCCCEEEEECCCHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCCCEEH
SRKIENLEFKKELENSLIKPSELGVTVRTKAQSASIFEIQEEIEELYRNYKEVIREGKFS
HHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
LNPKRLLGKGDLINKIIRDDIDAYTSSIIVDSIEDYERIKDSISNSEYLKVILYDDARSL
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHH
FDYYGIEKEILSLRNNRVNLNCGGDIVIEKTEAMYVIDVNSGKNTNHKNKEKTAYETNKN
HHHHCCHHHHHHHCCCEEEEECCCCEEEEECCEEEEEECCCCCCCCCCCCCHHHHHCCCC
AAIEIARQIKIRNLGGIILVDFIDMYSQENKKKILKILKDEFKSDSQRAKIFPFTELGLV
HHHHHHHHHEEECCCCEEEHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEECCCHHCCHH
QITRYRKGKSIYEYIEENCLACNGHGKRLKLSYINLLLRNEILKKNGEGKIKDFHIEINS
HHHHHHCCCHHHHHHHCCCEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEEEEEHH
IYEKDIRGNIFEFLKEIGALDLNIYLNFQESKDFYKVEPLIFKNQIESVKEYLVKNIEKY
HHHHHCCCHHHHHHHHHCCEEEEEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]