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The map label for this gene is obgE

Identifier: 18311109

GI number: 18311109

Start: 2438274

End: 2439560

Strand: Reverse

Name: obgE

Synonym: CPE2127

Alternate gene names: 18311109

Gene position: 2439560-2438274 (Counterclockwise)

Preceding gene: 18311110

Following gene: 18311108

Centisome position: 80.48

GC content: 35.04

Gene sequence:

>1287_bases
ATGTTTATAGATACGGCCAAGATATTTGTGAAATCTGGAGATGGTGGTCATGGTTCTGTTTCTTTTAGAAGAGAAAAATA
CGTTCCACTTGGTGGACCAGATGGTGGAGATGGTGGAAAAGGTGGAGATGTTACTTTTGTAGTAGATCCAGGAATGACAA
CTCTTTTAGATTTCAAATATAAGAGAAAATTCGTAGCAGGCAGAGGACAAGACGGTCAAGGTTCTAAATGTTACGGAAGA
GATGGTGAAAATTTAACAATAAAGGTTCCAATGGGAACTATAATAAGAGATGTTGAAACTAATAAGGTAATGGCAGACCT
TTCTCATAGAGATGATACATATACAATCTGTAGAGGAGGAAAAGGTGGTAAGGGAAATTGTAAGTTCTGTACACCTACAA
GACAGGCGCCAACTTTTGCTGAGCCAGGAATGCCAGGGGAAGAAAGATGGGTTGCTTTAGAATTAAAACTATTAGCAGAC
GTAGGTCTTTTAGGATTCCCTAACGTTGGAAAATCAACATTACTTTCAGTGGTAACTAAGGCTAAACCAAAGATAGCTAA
CTATCACTTCACAACTTTAAAACCTAATTTAGGAGTTGTTGCTGTACCAGGAATAGAGCCATTTGTTATGGCAGACGTAC
CAGGTATTATAGAAGGAGCTTCAGAGGGCGTAGGTCTTGGATTAGACTTCTTAAGACATATAGAAAGAACAAGACTTTTA
ATACACGTTGTTGATATTTCAGGAGTTGAAGGAAGAGACGCAGTCGAAGACTTCAAGAGAATCAACGAAGAATTAAAGAA
CTACAGTGTTAAACTTTGGGATAGACCTCAAATAGTAGTAGCAAATAAATGCGATATGTTATTTGATGAAGAAATTTTTG
AAAACTTCAAAGCTGAAGTTAATAAAATGGGATTTGATAAGGTATTTAAAATGTCAGCAGCTACTTCACAAGGAGTAGAG
GAAGTAATAAAAGAAGCAGCTAGAATGCTTAAAGATATTCCTGTTACTGACTTAGAAATCCCAGAAGATGAAAGATTTAT
TCCAGAGGATAAGAAGTTTACATATACTATAAATCCAATAGAAGAAGATGGATTAAAGGTTTATGTAGTAGAAGGTTCAT
TTGTAGACAGATTATTATTAGCTGTTAATGTAAATGATCCTGATTCATTAAGATATTTCCATAAGGTTCTTAATAATAAA
GGAATATTCCATGAGTTAAGAGAAATGGGAATAGAAGATGGAGATATGGTAAGATTAAACGACTTTGAGTTTGAATACTT
ACTATAA

Upstream 100 bases:

>100_bases
ATATGAGAACATAGCATTAAAAAAGCTGTGTTTTTATATTAAAGTAAGGTTATAATATACTAAAAAGGAACATTTTATAG
AGAAAGCAAGGTGAGAAAAC

Downstream 100 bases:

>100_bases
TTAATGGAGGATAAATAATGATAACAACAAAACAAAGAGCATATTTAAGAGGATTAGGTGCTAAATTAACTCCTATATTT
CAAATAGGTAAAAACGGAAT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MFIDTAKIFVKSGDGGHGSVSFRREKYVPLGGPDGGDGGKGGDVTFVVDPGMTTLLDFKYKRKFVAGRGQDGQGSKCYGR
DGENLTIKVPMGTIIRDVETNKVMADLSHRDDTYTICRGGKGGKGNCKFCTPTRQAPTFAEPGMPGEERWVALELKLLAD
VGLLGFPNVGKSTLLSVVTKAKPKIANYHFTTLKPNLGVVAVPGIEPFVMADVPGIIEGASEGVGLGLDFLRHIERTRLL
IHVVDISGVEGRDAVEDFKRINEELKNYSVKLWDRPQIVVANKCDMLFDEEIFENFKAEVNKMGFDKVFKMSAATSQGVE
EVIKEAARMLKDIPVTDLEIPEDERFIPEDKKFTYTINPIEEDGLKVYVVEGSFVDRLLLAVNVNDPDSLRYFHKVLNNK
GIFHELREMGIEDGDMVRLNDFEFEYLL

Sequences:

>Translated_428_residues
MFIDTAKIFVKSGDGGHGSVSFRREKYVPLGGPDGGDGGKGGDVTFVVDPGMTTLLDFKYKRKFVAGRGQDGQGSKCYGR
DGENLTIKVPMGTIIRDVETNKVMADLSHRDDTYTICRGGKGGKGNCKFCTPTRQAPTFAEPGMPGEERWVALELKLLAD
VGLLGFPNVGKSTLLSVVTKAKPKIANYHFTTLKPNLGVVAVPGIEPFVMADVPGIIEGASEGVGLGLDFLRHIERTRLL
IHVVDISGVEGRDAVEDFKRINEELKNYSVKLWDRPQIVVANKCDMLFDEEIFENFKAEVNKMGFDKVFKMSAATSQGVE
EVIKEAARMLKDIPVTDLEIPEDERFIPEDKKFTYTINPIEEDGLKVYVVEGSFVDRLLLAVNVNDPDSLRYFHKVLNNK
GIFHELREMGIEDGDMVRLNDFEFEYLL
>Mature_428_residues
MFIDTAKIFVKSGDGGHGSVSFRREKYVPLGGPDGGDGGKGGDVTFVVDPGMTTLLDFKYKRKFVAGRGQDGQGSKCYGR
DGENLTIKVPMGTIIRDVETNKVMADLSHRDDTYTICRGGKGGKGNCKFCTPTRQAPTFAEPGMPGEERWVALELKLLAD
VGLLGFPNVGKSTLLSVVTKAKPKIANYHFTTLKPNLGVVAVPGIEPFVMADVPGIIEGASEGVGLGLDFLRHIERTRLL
IHVVDISGVEGRDAVEDFKRINEELKNYSVKLWDRPQIVVANKCDMLFDEEIFENFKAEVNKMGFDKVFKMSAATSQGVE
EVIKEAARMLKDIPVTDLEIPEDERFIPEDKKFTYTINPIEEDGLKVYVVEGSFVDRLLLAVNVNDPDSLRYFHKVLNNK
GIFHELREMGIEDGDMVRLNDFEFEYLL

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=322, Percent_Identity=41.9254658385093, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI111955139, Length=346, Percent_Identity=34.971098265896, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI111955063, Length=180, Percent_Identity=37.7777777777778, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI58761500, Length=129, Percent_Identity=34.8837209302326, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=35.5932203389831, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI4557537, Length=114, Percent_Identity=35.0877192982456, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789574, Length=353, Percent_Identity=45.3257790368272, Blast_Score=265, Evalue=3e-72,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=36.231884057971, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790615, Length=210, Percent_Identity=25.7142857142857, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=285, Percent_Identity=38.9473684210526, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17552324, Length=309, Percent_Identity=33.0097087378641, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=35.9712230215827, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=34.7457627118644, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=183, Percent_Identity=40.4371584699454, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=37.3015873015873, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=34.9206349206349, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585318, Length=355, Percent_Identity=34.3661971830986, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI20129375, Length=263, Percent_Identity=39.1634980988593, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=36.4341085271318, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=36.4341085271318, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=36.4341085271318, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356473, Length=89, Percent_Identity=42.6966292134831, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_CLOP1 (Q0TNI5)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696805.1
- ProteinModelPortal:   Q0TNI5
- SMR:   Q0TNI5
- STRING:   Q0TNI5
- GeneID:   4201168
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2382
- TIGR:   CPF_2382
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12297
- BioCyc:   CPER195103:CPF_2382-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 47501; Mature: 47501

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDTAKIFVKSGDGGHGSVSFRREKYVPLGGPDGGDGGKGGDVTFVVDPGMTTLLDFKY
CEEEEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
KRKFVAGRGQDGQGSKCYGRDGENLTIKVPMGTIIRDVETNKVMADLSHRDDTYTICRGG
HHHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHCCCCHHHHHHCCCCCEEEEEECC
KGGKGNCKFCTPTRQAPTFAEPGMPGEERWVALELKLLADVGLLGFPNVGKSTLLSVVTK
CCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
AKPKIANYHFTTLKPNLGVVAVPGIEPFVMADVPGIIEGASEGVGLGLDFLRHIERTRLL
CCCCCCCEEEEEECCCCCEEEECCCCCEEEECCCHHHCCCCCCCCCCHHHHHHHHHCEEE
IHVVDISGVEGRDAVEDFKRINEELKNYSVKLWDRPQIVVANKCDMLFDEEIFENFKAEV
EEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHH
NKMGFDKVFKMSAATSQGVEEVIKEAARMLKDIPVTDLEIPEDERFIPEDKKFTYTINPI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCC
EEDGLKVYVVEGSFVDRLLLAVNVNDPDSLRYFHKVLNNKGIFHELREMGIEDGDMVRLN
CCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
DFEFEYLL
CCCEEEEC
>Mature Secondary Structure
MFIDTAKIFVKSGDGGHGSVSFRREKYVPLGGPDGGDGGKGGDVTFVVDPGMTTLLDFKY
CEEEEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
KRKFVAGRGQDGQGSKCYGRDGENLTIKVPMGTIIRDVETNKVMADLSHRDDTYTICRGG
HHHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHCCCCHHHHHHCCCCCEEEEEECC
KGGKGNCKFCTPTRQAPTFAEPGMPGEERWVALELKLLADVGLLGFPNVGKSTLLSVVTK
CCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
AKPKIANYHFTTLKPNLGVVAVPGIEPFVMADVPGIIEGASEGVGLGLDFLRHIERTRLL
CCCCCCCEEEEEECCCCCEEEECCCCCEEEECCCHHHCCCCCCCCCCHHHHHHHHHCEEE
IHVVDISGVEGRDAVEDFKRINEELKNYSVKLWDRPQIVVANKCDMLFDEEIFENFKAEV
EEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHH
NKMGFDKVFKMSAATSQGVEEVIKEAARMLKDIPVTDLEIPEDERFIPEDKKFTYTINPI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCC
EEDGLKVYVVEGSFVDRLLLAVNVNDPDSLRYFHKVLNNKGIFHELREMGIEDGDMVRLN
CCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
DFEFEYLL
CCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA