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The map label for this gene is moaC

Identifier: 18311065

GI number: 18311065

Start: 2390899

End: 2391375

Strand: Reverse

Name: moaC

Synonym: CPE2083

Alternate gene names: 18311065

Gene position: 2391375-2390899 (Counterclockwise)

Preceding gene: 18311066

Following gene: 18311064

Centisome position: 78.89

GC content: 31.03

Gene sequence:

>477_bases
ATGGATAATAAACTTACTCATTTCGATAATAAAGGAAATGCAGTTATGGTAGATGTAAGCAATAAAAATGAAACTGAAAG
AATAGCTATTGCAACAGGAACTGTAAAGGCATCAAGTGAAACTATAGAATTAATAAAATCAGGTCAAATAGGAAAGGGAG
ATGTTTTAGGTGTTGCTAGAGTTGCAGGTATAATGGCAATGAAAAATACTAGTAATTTAATACCTATGTGTCATCCTGTT
ATGATTACAGGATCTAGTATTGATTTTGAAATTGATTCTGAAAAAAATGAAATAAGGATAACAGCTACTTCAAAGGTAGT
TCATAAAACAGGAGTTGAAATGGAGGCTCTTACAGGAGTATCTATTGCAGCCCTTACTATTTATGATATGTGCAAAGCTG
TAGATAAAAGAATGGTTATAGGAGATATACACCTAGTAAAAAAACTAGGTGGAAAAAGTGGAGAATTTAATTTTTAA

Upstream 100 bases:

>100_bases
TAGTTTTAATATCAGTGATTTTAACTTTTTCTTATAATAAAATAATTAAGAGAATAAAATAGAATTTTTAAAGTTTAGAG
AAGAGGAGAGAGTAACATAT

Downstream 100 bases:

>100_bases
ATTGTTTATGTGAAAAAGTGAGTTAGAGTTTAGCCTCTAACTCTTTTTTTTATTATAAATATAAGTATATAAATTATATA
TTTTATGGACTTTCTATTGT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MDNKLTHFDNKGNAVMVDVSNKNETERIAIATGTVKASSETIELIKSGQIGKGDVLGVARVAGIMAMKNTSNLIPMCHPV
MITGSSIDFEIDSEKNEIRITATSKVVHKTGVEMEALTGVSIAALTIYDMCKAVDKRMVIGDIHLVKKLGGKSGEFNF

Sequences:

>Translated_158_residues
MDNKLTHFDNKGNAVMVDVSNKNETERIAIATGTVKASSETIELIKSGQIGKGDVLGVARVAGIMAMKNTSNLIPMCHPV
MITGSSIDFEIDSEKNEIRITATSKVVHKTGVEMEALTGVSIAALTIYDMCKAVDKRMVIGDIHLVKKLGGKSGEFNF
>Mature_158_residues
MDNKLTHFDNKGNAVMVDVSNKNETERIAIATGTVKASSETIELIKSGQIGKGDVLGVARVAGIMAMKNTSNLIPMCHPV
MITGSSIDFEIDSEKNEIRITATSKVVHKTGVEMEALTGVSIAALTIYDMCKAVDKRMVIGDIHLVKKLGGKSGEFNF

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=52.258064516129, Blast_Score=162, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=46.3087248322148, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=46, Blast_Score=140, Evalue=4e-34,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=45.985401459854, Blast_Score=126, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_CLOP1 (Q0TNM7)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696763.1
- ProteinModelPortal:   Q0TNM7
- SMR:   Q0TNM7
- STRING:   Q0TNM7
- GeneID:   4202445
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2340
- TIGR:   CPF_2340
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK09364
- BioCyc:   CPER195103:CPF_2340-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 16955; Mature: 16955

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKLTHFDNKGNAVMVDVSNKNETERIAIATGTVKASSETIELIKSGQIGKGDVLGVAR
CCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCEECCHHHHHHHHCCCCCCCCHHHHHH
VAGIMAMKNTSNLIPMCHPVMITGSSIDFEIDSEKNEIRITATSKVVHKTGVEMEALTGV
HHHHHEECCCCCCCCCCCEEEEECCEEEEEECCCCCEEEEEEEEEEHHHCCCCEEHHCCC
SIAALTIYDMCKAVDKRMVIGDIHLVKKLGGKSGEFNF
HHHHHHHHHHHHHHHCEEEEHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDNKLTHFDNKGNAVMVDVSNKNETERIAIATGTVKASSETIELIKSGQIGKGDVLGVAR
CCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCEECCHHHHHHHHCCCCCCCCHHHHHH
VAGIMAMKNTSNLIPMCHPVMITGSSIDFEIDSEKNEIRITATSKVVHKTGVEMEALTGV
HHHHHEECCCCCCCCCCCEEEEECCEEEEEECCCCCEEEEEEEEEEHHHCCCCEEHHCCC
SIAALTIYDMCKAVDKRMVIGDIHLVKKLGGKSGEFNF
HHHHHHHHHHHHHHHCEEEEHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA