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The map label for this gene is selU [H]

Identifier: 18311052

GI number: 18311052

Start: 2370650

End: 2371720

Strand: Reverse

Name: selU [H]

Synonym: CPE2070

Alternate gene names: 18311052

Gene position: 2371720-2370650 (Counterclockwise)

Preceding gene: 18311053

Following gene: 18311051

Centisome position: 78.24

GC content: 29.88

Gene sequence:

>1071_bases
ATGTTTGGATTAATAAGTTATGAGGAGATATATGGACATGAGGACGAGTATATCTTTATAGATGTTAGAAGCCAAAAGGA
AGCCTTTGAAGAACCTATGATAGGGTCTGTAAATATTCCAGTGCTTTTAAATGAAGAGAGAGATGTAGTCGGAACTTTAT
ATGTTAGAGAAAGTGCAGAGGCTGCAAAAGAGCAAGGAATAGAATTCATCTCTAGAAGACTCCCTGAAATATTTAAACAA
GTTCAAGAGCTTTATAGAAATAAGCATGGTAAAAAACTTGTTATTTTTTGTGCAAGAGGTGGAATGAGAAGTGGAAGTCT
ACATTCATTACTAAATAGTTTAGGAATAAATTGTTATAAATTAGAAGGCGGATATAAAGCGTATAGAAGTTTTATGATAA
ATAAAATAGAAGAATTCTCAAAAGAAATTGATTTTATAGTATTATACGGAAATACTGGTGTAGGAAAAACAGAAATGTTA
TATAAATTAGAAGAAAAGGGATATGATGTTTTAGATTTAGAAGGATGTGCAAATCATAGAGGTTCAATTCTTGGAGGAGT
TGGATTAGGTGAGTGCAATACTCAAAAGAGATTTGATGCATTAGTTTATGATAAACTTAGACATAGAAATTCTAACATTG
TATTCATTGAAGGAGAAAGTAAAAGAATAGGAAGAATTTTAATACCAGATCCTTTATTTGAAAAGATGTATGAAGGTGCA
AAAATTAAAATAAGTGCTGATCTAGAGATTAGAGCAGAGCGATTAGTTAAGGAATATACTGCCTTTGAAAATGTAAATGA
ACAATTAGATGAAGCTTTAGGAGTTCTTAAAAAGCATATAAGTCAAGAAAGAGTGGAACAATATAAAGACTTAGTAGCCA
AAGGTGATTATAAGAAAGTAGCCTTAGAACTTATGGAAAAATATTATGATCCTAGATATGGAACAAGTGCAAAGAAAAAA
ACATTTAGAAATGAATTAGAGATAAATGACATAGAAAATGAATTATTTAAATTAGAGGAAATATATAAAGAGATTTCAGA
GGAATTAAGGGAGGATGTATATGAGCAATAA

Upstream 100 bases:

>100_bases
ATCGTGAAGTACTATAAAGATATGTTCGATGGGAACAAATGTTTGACAATGTATTTTAAAGAATTATACTATTTTAGTAA
ATTGAAAGGATGATATATAA

Downstream 100 bases:

>100_bases
AAATAACAATTATGATGTTACCTCTTTAACTTCTTTAGAAAAGTTAGAACCAGTAAGAGTAAGACCAGGAATGTACATAG
GTTCTACAGGAAGCAAGGGA

Product: tRNA 2-selenouridine synthase

Products: NA

Alternate protein names: Selenophosphate-dependent tRNA 2-selenouridine synthase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MFGLISYEEIYGHEDEYIFIDVRSQKEAFEEPMIGSVNIPVLLNEERDVVGTLYVRESAEAAKEQGIEFISRRLPEIFKQ
VQELYRNKHGKKLVIFCARGGMRSGSLHSLLNSLGINCYKLEGGYKAYRSFMINKIEEFSKEIDFIVLYGNTGVGKTEML
YKLEEKGYDVLDLEGCANHRGSILGGVGLGECNTQKRFDALVYDKLRHRNSNIVFIEGESKRIGRILIPDPLFEKMYEGA
KIKISADLEIRAERLVKEYTAFENVNEQLDEALGVLKKHISQERVEQYKDLVAKGDYKKVALELMEKYYDPRYGTSAKKK
TFRNELEINDIENELFKLEEIYKEISEELREDVYEQ

Sequences:

>Translated_356_residues
MFGLISYEEIYGHEDEYIFIDVRSQKEAFEEPMIGSVNIPVLLNEERDVVGTLYVRESAEAAKEQGIEFISRRLPEIFKQ
VQELYRNKHGKKLVIFCARGGMRSGSLHSLLNSLGINCYKLEGGYKAYRSFMINKIEEFSKEIDFIVLYGNTGVGKTEML
YKLEEKGYDVLDLEGCANHRGSILGGVGLGECNTQKRFDALVYDKLRHRNSNIVFIEGESKRIGRILIPDPLFEKMYEGA
KIKISADLEIRAERLVKEYTAFENVNEQLDEALGVLKKHISQERVEQYKDLVAKGDYKKVALELMEKYYDPRYGTSAKKK
TFRNELEINDIENELFKLEEIYKEISEELREDVYEQ
>Mature_356_residues
MFGLISYEEIYGHEDEYIFIDVRSQKEAFEEPMIGSVNIPVLLNEERDVVGTLYVRESAEAAKEQGIEFISRRLPEIFKQ
VQELYRNKHGKKLVIFCARGGMRSGSLHSLLNSLGINCYKLEGGYKAYRSFMINKIEEFSKEIDFIVLYGNTGVGKTEML
YKLEEKGYDVLDLEGCANHRGSILGGVGLGECNTQKRFDALVYDKLRHRNSNIVFIEGESKRIGRILIPDPLFEKMYEGA
KIKISADLEIRAERLVKEYTAFENVNEQLDEALGVLKKHISQERVEQYKDLVAKGDYKKVALELMEKYYDPRYGTSAKKK
TFRNELEINDIENELFKLEEIYKEISEELREDVYEQ

Specific function: Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA [H]

COG id: COG2603

COG function: function code R; Predicted ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1786712, Length=349, Percent_Identity=30.3724928366762, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR017582 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 41252; Mature: 41252

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGLISYEEIYGHEDEYIFIDVRSQKEAFEEPMIGSVNIPVLLNEERDVVGTLYVRESAE
CCCCCCHHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCCCEEECCCCCEEEEEEEHHHHH
AAKEQGIEFISRRLPEIFKQVQELYRNKHGKKLVIFCARGGMRSGSLHSLLNSLGINCYK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCCEEEE
LEGGYKAYRSFMINKIEEFSKEIDFIVLYGNTGVGKTEMLYKLEEKGYDVLDLEGCANHR
ECCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCC
GSILGGVGLGECNTQKRFDALVYDKLRHRNSNIVFIEGESKRIGRILIPDPLFEKMYEGA
CCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCHHHHHHHCCC
KIKISADLEIRAERLVKEYTAFENVNEQLDEALGVLKKHISQERVEQYKDLVAKGDYKKV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ALELMEKYYDPRYGTSAKKKTFRNELEINDIENELFKLEEIYKEISEELREDVYEQ
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFGLISYEEIYGHEDEYIFIDVRSQKEAFEEPMIGSVNIPVLLNEERDVVGTLYVRESAE
CCCCCCHHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCCCEEECCCCCEEEEEEEHHHHH
AAKEQGIEFISRRLPEIFKQVQELYRNKHGKKLVIFCARGGMRSGSLHSLLNSLGINCYK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCCEEEE
LEGGYKAYRSFMINKIEEFSKEIDFIVLYGNTGVGKTEMLYKLEEKGYDVLDLEGCANHR
ECCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCC
GSILGGVGLGECNTQKRFDALVYDKLRHRNSNIVFIEGESKRIGRILIPDPLFEKMYEGA
CCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCHHHHHHHCCC
KIKISADLEIRAERLVKEYTAFENVNEQLDEALGVLKKHISQERVEQYKDLVAKGDYKKV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ALELMEKYYDPRYGTSAKKKTFRNELEINDIENELFKLEEIYKEISEELREDVYEQ
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA