Click here to switch to the map view.

The map label for this gene is glsA2

Identifier: 18310977

GI number: 18310977

Start: 2286083

End: 2287000

Strand: Reverse

Name: glsA2

Synonym: CPE1995

Alternate gene names: 18310977

Gene position: 2287000-2286083 (Counterclockwise)

Preceding gene: 18310980

Following gene: 18310976

Centisome position: 75.44

GC content: 30.5

Gene sequence:

>918_bases
GTGAAAAATTTTCTTGAGAGTTTAATAGAAAATAATAGACAATATGTTGAACATGGAAAACTGGCATCTTATATTCCAGA
ATTAGAAAAAGCAAATAAAGAAGATTTAGGTATATATATAGTTACTCTTGATGGAAAAGAGGTAGGGGCAGGAGAGTATG
ATAAAAAGTTTACTATTCAGAGTATATCAAAAGTAATAACTTTAATGCTTGCAATATTAGATAATGGAAAAGATAGAGTA
TTTTCAAGAGTAGGTGTTGAACCAACTGGAGATAGCTTTAATAGTATAGTAAGTTTAGAGAGAAAGCCCTCTAAAAAACC
TTTTAACCCTATGGTTAATTCAGGGGCTATATTAACAACATCTTTAATTGAAGGTGATAGTGAAGAGGAAAAGTTTGAGA
GAATTTTAGAATTTACTAGAAAAGTAACAGGAAATGATGATATTCAATTAAATGAAGATGTTTATTTATCTGAAAAGGAA
ACTGGAGATAGAAATAGAGCCTTAGCATACTTTATGAAAAGTAATGGAGTTATAGAAGGAAATATAGATGATATATTAGA
TTTATATTTCAAACAATGTTCTCTAGAAGTTAATGCTAAAGATTTAGCTAGATTTGGTGCTATGCTTGCTAATGATGGAG
TATTACCTTGGAATGGAGAAAGAGTAATATCTAGAGAAATTTGCAGAATAATAAAAACAATAATGGTTACTTGCGGTATG
TATGATGACTCAGGTAAATTTGCTGTACATATAGGAATTCCAGCAAAAAGTGGAGTTGGTGGCGGAATAATGGCTGCTGT
TCCAAGAAGAATGGGAATAGGTATTTTTGGACCTTCTTTAGATGATAAGGGAAATAGTATAGCAGGAACACATGTTATGA
AGGATTTATCTGAGGAATTAGATTTAAGTATTTTCTAA

Upstream 100 bases:

>100_bases
ATTTTAAAAGATTTATAATAATTCGTTGAAAATGTTATAATGTTTATATATTAATTATTAATTTATTGAATAAAAAAATT
AAACTAAGGAGCGAACAAAA

Downstream 100 bases:

>100_bases
AATGTGTTAATATTATTAGAACTAATGGGAAAAATCATTAAAAGAGATGATTGTTTAAAAGTCTAAAATAAACTTATAAA
TAGTATGAAAAGAATATCTG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKNFLESLIENNRQYVEHGKLASYIPELEKANKEDLGIYIVTLDGKEVGAGEYDKKFTIQSISKVITLMLAILDNGKDRV
FSRVGVEPTGDSFNSIVSLERKPSKKPFNPMVNSGAILTTSLIEGDSEEEKFERILEFTRKVTGNDDIQLNEDVYLSEKE
TGDRNRALAYFMKSNGVIEGNIDDILDLYFKQCSLEVNAKDLARFGAMLANDGVLPWNGERVISREICRIIKTIMVTCGM
YDDSGKFAVHIGIPAKSGVGGGIMAAVPRRMGIGIFGPSLDDKGNSIAGTHVMKDLSEELDLSIF

Sequences:

>Translated_305_residues
MKNFLESLIENNRQYVEHGKLASYIPELEKANKEDLGIYIVTLDGKEVGAGEYDKKFTIQSISKVITLMLAILDNGKDRV
FSRVGVEPTGDSFNSIVSLERKPSKKPFNPMVNSGAILTTSLIEGDSEEEKFERILEFTRKVTGNDDIQLNEDVYLSEKE
TGDRNRALAYFMKSNGVIEGNIDDILDLYFKQCSLEVNAKDLARFGAMLANDGVLPWNGERVISREICRIIKTIMVTCGM
YDDSGKFAVHIGIPAKSGVGGGIMAAVPRRMGIGIFGPSLDDKGNSIAGTHVMKDLSEELDLSIF
>Mature_305_residues
MKNFLESLIENNRQYVEHGKLASYIPELEKANKEDLGIYIVTLDGKEVGAGEYDKKFTIQSISKVITLMLAILDNGKDRV
FSRVGVEPTGDSFNSIVSLERKPSKKPFNPMVNSGAILTTSLIEGDSEEEKFERILEFTRKVTGNDDIQLNEDVYLSEKE
TGDRNRALAYFMKSNGVIEGNIDDILDLYFKQCSLEVNAKDLARFGAMLANDGVLPWNGERVISREICRIIKTIMVTCGM
YDDSGKFAVHIGIPAKSGVGGGIMAAVPRRMGIGIFGPSLDDKGNSIAGTHVMKDLSEELDLSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=281, Percent_Identity=42.3487544483986, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI20336214, Length=281, Percent_Identity=41.6370106761566, Blast_Score=217, Evalue=1e-56,
Organism=Escherichia coli, GI1787804, Length=301, Percent_Identity=39.5348837209302, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI1786693, Length=287, Percent_Identity=40.0696864111498, Blast_Score=218, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI17507019, Length=301, Percent_Identity=39.8671096345515, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17532727, Length=290, Percent_Identity=40.6896551724138, Blast_Score=229, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI193204073, Length=310, Percent_Identity=36.7741935483871, Blast_Score=214, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI193204075, Length=312, Percent_Identity=36.5384615384615, Blast_Score=208, Evalue=2e-54,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=40.7017543859649, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=40.7017543859649, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=40.7017543859649, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=40.7017543859649, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=40.7017543859649, Blast_Score=228, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=40.7017543859649, Blast_Score=228, Evalue=5e-60,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=40.7017543859649, Blast_Score=227, Evalue=6e-60,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=40.7017543859649, Blast_Score=227, Evalue=6e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA2_CLOPE (Q8XIW8)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_562911.1
- ProteinModelPortal:   Q8XIW8
- SMR:   Q8XIW8
- GeneID:   990310
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE1995
- NMPDR:   fig|195102.1.peg.2058
- HOGENOM:   HBG512335
- OMA:   RNASIAY
- PhylomeDB:   Q8XIW8
- ProtClustDB:   PRK00971
- BioCyc:   CPER195102:CPE1995-MONOMER
- BRENDA:   3.5.1.2
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 33691; Mature: 33691

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFLESLIENNRQYVEHGKLASYIPELEKANKEDLGIYIVTLDGKEVGAGEYDKKFTIQ
CHHHHHHHHHCCHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHH
SISKVITLMLAILDNGKDRVFSRVGVEPTGDSFNSIVSLERKPSKKPFNPMVNSGAILTT
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHEECCCCCCCCCCCCCCCCCCEEEE
SLIEGDSEEEKFERILEFTRKVTGNDDIQLNEDVYLSEKETGDRNRALAYFMKSNGVIEG
HHHCCCCHHHHHHHHHHHHHHCCCCCCEEECCCEEECCCCCCCCCCEEEEEEECCCEEEC
NIDDILDLYFKQCSLEVNAKDLARFGAMLANDGVLPWNGERVISREICRIIKTIMVTCGM
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
YDDSGKFAVHIGIPAKSGVGGGIMAAVPRRMGIGIFGPSLDDKGNSIAGTHVMKDLSEEL
EECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHC
DLSIF
CCCCC
>Mature Secondary Structure
MKNFLESLIENNRQYVEHGKLASYIPELEKANKEDLGIYIVTLDGKEVGAGEYDKKFTIQ
CHHHHHHHHHCCHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHH
SISKVITLMLAILDNGKDRVFSRVGVEPTGDSFNSIVSLERKPSKKPFNPMVNSGAILTT
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHEECCCCCCCCCCCCCCCCCCEEEE
SLIEGDSEEEKFERILEFTRKVTGNDDIQLNEDVYLSEKETGDRNRALAYFMKSNGVIEG
HHHCCCCHHHHHHHHHHHHHHCCCCCCEEECCCEEECCCCCCCCCCEEEEEEECCCEEEC
NIDDILDLYFKQCSLEVNAKDLARFGAMLANDGVLPWNGERVISREICRIIKTIMVTCGM
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
YDDSGKFAVHIGIPAKSGVGGGIMAAVPRRMGIGIFGPSLDDKGNSIAGTHVMKDLSEEL
EECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHC
DLSIF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842