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The map label for this gene is ppaX

Identifier: 18310959

GI number: 18310959

Start: 2264387

End: 2265031

Strand: Reverse

Name: ppaX

Synonym: CPE1977

Alternate gene names: 18310959

Gene position: 2265031-2264387 (Counterclockwise)

Preceding gene: 18310965

Following gene: 18310957

Centisome position: 74.72

GC content: 29.92

Gene sequence:

>645_bases
ATGATAAAAGCAGTATTGTTTGACCTAGATGGAACATTGATAAATACTAATGATTTAATACTAAAATCATTTAAACATAC
ATTTAAAACTATGTTAGATTTAGAGCCAAGTGAAGAAGAGATTACTATGAACTATGGTAGACCATTGCAGGAAATTTTTA
AATCCTATGATGAAAATAGAATAGAAGAAATGATTAATTGTTATAGAAAAATAAACTTAGAATTACATGATGATGAATGT
AAAGAGTTTGCTGACGTAGATTTAATGCTAAAAACATTAAAGAGTAAAGGAATTAAAATTGGAGTTGTAACTTCAAAGAA
AAGTGATATGGCAGAGCGTGGAGCTAAATTAATGGGTATATTTAAGTATTTTGATACTTTTATAACTCCTGAAATTACTA
CAAAGCATAAGCCAGATGGGGAGCCAGTTTTAAAGGCTTGTGAAAATTTAGGAGTATCTCCTAGTGAAGCTCTTATGGTA
GGTGATTCACCTTACGATATTTTAGCAGGTAAAAATGCTGGAGCTAAGACCTGTGGAGTTAAATACACAGCATTGCCTCT
TGAAAAATTAGGAGAGAGTAACCCAGACTTTTATGTAGATAAACCTTTAGAAATTTTAGATCTTGTTGAAAAATTAAATT
CTTAA

Upstream 100 bases:

>100_bases
TTTGTGAAGGGGTTTTTTAAAATTTTTTTAAATTTATGATATAATTATTAAAAATATATATATTTTAAAGCTGATTTTTA
AAATAATAAAGGAGAAATTT

Downstream 100 bases:

>100_bases
TTTAATAGGTTTTTAATAAAAAAAGATTTAGTCTAAGACTAAATCTTTTTTTTATTAAAATATATTTCTTCTACGTCTTC
TACGTTTTCTTAAATTTATT

Product: pyrophosphatase PpaX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MIKAVLFDLDGTLINTNDLILKSFKHTFKTMLDLEPSEEEITMNYGRPLQEIFKSYDENRIEEMINCYRKINLELHDDEC
KEFADVDLMLKTLKSKGIKIGVVTSKKSDMAERGAKLMGIFKYFDTFITPEITTKHKPDGEPVLKACENLGVSPSEALMV
GDSPYDILAGKNAGAKTCGVKYTALPLEKLGESNPDFYVDKPLEILDLVEKLNS

Sequences:

>Translated_214_residues
MIKAVLFDLDGTLINTNDLILKSFKHTFKTMLDLEPSEEEITMNYGRPLQEIFKSYDENRIEEMINCYRKINLELHDDEC
KEFADVDLMLKTLKSKGIKIGVVTSKKSDMAERGAKLMGIFKYFDTFITPEITTKHKPDGEPVLKACENLGVSPSEALMV
GDSPYDILAGKNAGAKTCGVKYTALPLEKLGESNPDFYVDKPLEILDLVEKLNS
>Mature_214_residues
MIKAVLFDLDGTLINTNDLILKSFKHTFKTMLDLEPSEEEITMNYGRPLQEIFKSYDENRIEEMINCYRKINLELHDDEC
KEFADVDLMLKTLKSKGIKIGVVTSKKSDMAERGAKLMGIFKYFDTFITPEITTKHKPDGEPVLKACENLGVSPSEALMV
GDSPYDILAGKNAGAKTCGVKYTALPLEKLGESNPDFYVDKPLEILDLVEKLNS

Specific function: Unknown

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family

Homologues:

Organism=Escherichia coli, GI1789787, Length=220, Percent_Identity=27.7272727272727, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPAX_CLOPE (Q8XIY6)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_562893.1
- ProteinModelPortal:   Q8XIY6
- SMR:   Q8XIY6
- GeneID:   990291
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE1977
- NMPDR:   fig|195102.1.peg.2040
- HOGENOM:   HBG742904
- OMA:   IEEMINC
- ProtClustDB:   PRK13288
- BioCyc:   CPER195102:CPE1977-MONOMER
- BRENDA:   3.6.1.1
- HAMAP:   MF_01250
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- Gene3D:   G3DSA:3.40.50.1000
- PRINTS:   PR00413
- TIGRFAMs:   TIGR01549
- TIGRFAMs:   TIGR01509

Pfam domain/function: PF00702 Hydrolase; SSF56784 SSF56784

EC number: =3.6.1.1

Molecular weight: Translated: 24081; Mature: 24081

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: ACT_SITE 8-8

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAVLFDLDGTLINTNDLILKSFKHTFKTMLDLEPSEEEITMNYGRPLQEIFKSYDENR
CCEEEEEECCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHCHHH
IEEMINCYRKINLELHDDECKEFADVDLMLKTLKSKGIKIGVVTSKKSDMAERGAKLMGI
HHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
FKYFDTFITPEITTKHKPDGEPVLKACENLGVSPSEALMVGDSPYDILAGKNAGAKTCGV
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCCCCCCC
KYTALPLEKLGESNPDFYVDKPLEILDLVEKLNS
EEEECCHHHHCCCCCCEEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MIKAVLFDLDGTLINTNDLILKSFKHTFKTMLDLEPSEEEITMNYGRPLQEIFKSYDENR
CCEEEEEECCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHCHHH
IEEMINCYRKINLELHDDECKEFADVDLMLKTLKSKGIKIGVVTSKKSDMAERGAKLMGI
HHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
FKYFDTFITPEITTKHKPDGEPVLKACENLGVSPSEALMVGDSPYDILAGKNAGAKTCGV
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCCCCCCC
KYTALPLEKLGESNPDFYVDKPLEILDLVEKLNS
EEEECCHHHHCCCCCCEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842