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The map label for this gene is dtd

Identifier: 18310919

GI number: 18310919

Start: 2219159

End: 2219608

Strand: Reverse

Name: dtd

Synonym: CPE1937

Alternate gene names: 18310919

Gene position: 2219608-2219159 (Counterclockwise)

Preceding gene: 18310920

Following gene: 18310918

Centisome position: 73.22

GC content: 32.89

Gene sequence:

>450_bases
GTGAGAGTTGTAGTTCAAAGAGTGAATAAATCCTCTGTTAAAGTGGATAATGAGATAGTTGGAAGTATAAATAAAGGCTT
TAATGTATTAGTTGGAATTGGCAAAGAGGATACTATTGAAGACTTAAAATATATGAAAGATAAGGTCTTAAACTTAAGAG
TTTTTGAAGATGAAGAAGATAAAATGAATTTATCTTTAAAGGATGTTTGTGGAGAACTACTTCTTATATCGCAATTTACC
CTTTATGGAGACTGTAGAAAGGGAAGAAGACCAAATTTCATGAATGCTCTTGGAGGGGATGAAGCTAAGAAACTTTTTGA
TGAGTTTGTAAGCATGTGCAGAGAAGAGGGCATAAAAGTTGAAACTGGAGTCTTTGGTGCCCATATGGTAGTTGACATAG
AAAATGATGGGCCTGTAACTTTAATTTTAGATAGCAAAAAGAATTTCTAA

Upstream 100 bases:

>100_bases
TTGATAATATAGAACAATTAAAAGAATTAATGAAGAAAATAAGAAGACTACAAGGAATATTAGACGTTTATAGAGTAAAT
AAATAAAAGGGGGCATAATC

Downstream 100 bases:

>100_bases
ACAAATATTACTATTTTGTGTATAAAGCATTATAATAAATATAGGCTTTTAGAAAAGTTAAACATTGAAAGTTTTTATAG
GAGTTTAGCTTAATAAGTTA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRVVVQRVNKSSVKVDNEIVGSINKGFNVLVGIGKEDTIEDLKYMKDKVLNLRVFEDEEDKMNLSLKDVCGELLLISQFT
LYGDCRKGRRPNFMNALGGDEAKKLFDEFVSMCREEGIKVETGVFGAHMVVDIENDGPVTLILDSKKNF

Sequences:

>Translated_149_residues
MRVVVQRVNKSSVKVDNEIVGSINKGFNVLVGIGKEDTIEDLKYMKDKVLNLRVFEDEEDKMNLSLKDVCGELLLISQFT
LYGDCRKGRRPNFMNALGGDEAKKLFDEFVSMCREEGIKVETGVFGAHMVVDIENDGPVTLILDSKKNF
>Mature_149_residues
MRVVVQRVNKSSVKVDNEIVGSINKGFNVLVGIGKEDTIEDLKYMKDKVLNLRVFEDEEDKMNLSLKDVCGELLLISQFT
LYGDCRKGRRPNFMNALGGDEAKKLFDEFVSMCREEGIKVETGVFGAHMVVDIENDGPVTLILDSKKNF

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=43.6241610738255, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=41.2587412587413, Blast_Score=124, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=46, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=42.6666666666667, Blast_Score=120, Evalue=6e-29,
Organism=Drosophila melanogaster, GI281361569, Length=150, Percent_Identity=45.3333333333333, Blast_Score=128, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_CLOP1 (Q0TP24)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696616.1
- ProteinModelPortal:   Q0TP24
- SMR:   Q0TP24
- STRING:   Q0TP24
- GeneID:   4201163
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2192
- TIGR:   CPF_2192
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   CPER195103:CPF_2192-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16781; Mature: 16781

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVVQRVNKSSVKVDNEIVGSINKGFNVLVGIGKEDTIEDLKYMKDKVLNLRVFEDEED
CCCEEEECCCCCEEECHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEEECCCC
KMNLSLKDVCGELLLISQFTLYGDCRKGRRPNFMNALGGDEAKKLFDEFVSMCREEGIKV
CCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCEE
ETGVFGAHMVVDIENDGPVTLILDSKKNF
ECCCCEEEEEEEECCCCCEEEEECCCCCC
>Mature Secondary Structure
MRVVVQRVNKSSVKVDNEIVGSINKGFNVLVGIGKEDTIEDLKYMKDKVLNLRVFEDEED
CCCEEEECCCCCEEECHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEEECCCC
KMNLSLKDVCGELLLISQFTLYGDCRKGRRPNFMNALGGDEAKKLFDEFVSMCREEGIKV
CCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCEE
ETGVFGAHMVVDIENDGPVTLILDSKKNF
ECCCCEEEEEEEECCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA