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The map label for this gene is pyrR

Identifier: 18310831

GI number: 18310831

Start: 2120427

End: 2120963

Strand: Reverse

Name: pyrR

Synonym: CPE1849

Alternate gene names: 18310831

Gene position: 2120963-2120427 (Counterclockwise)

Preceding gene: 18310832

Following gene: 18310830

Centisome position: 69.97

GC content: 31.66

Gene sequence:

>537_bases
ATGCATCTTAAGGCAAGTTTATTAGATGAAAATGCTATAAGAAGAGCGCTTACAAGACTTTCACATGAGATAATAGAAAA
GAATAAAGGGGTAGAGGATATAGTTCTTGTTGGAATTAAGAGAAGAGGATATCCTTTAGCAGAGAGACTTTCAGAGTTTA
TAGAAAAGTTTGAAGGTGTTAAAATTCCTGTTGCTAGTGTTGACATAACATTATACAGAGATGATTTAACTAATGTTAGT
GATACACCGAATTTAAATGATCCTAAAATAGATGTGGATATAAGAGGGAAAAAGGTTATTATAGTTGATGATGTTTTATA
TACTTGTAGAACAGCTAGGGCAGCTATTGATGCAATAATGGATCAAGGAAGACCAGAATTTATACAGTTAGCTGTTTTAG
TAGATAGAGGACACAAGGAATTACCAATAAGAGCTGACTATGTTGGAAAGAATATTCCTACATCAAAGGATGAAATAATA
AAGGTTCAAATCAAAGAGATTGATGGAACTGATTCAGTTGAAATATATGAAAATTAA

Upstream 100 bases:

>100_bases
AGGATTTATTCATCCTACTACTGGAGAATATGTTGAATTTGACTCAGAATTGCCAGAGTACTTTGAAAAAATTGTAGAGA
AATTAGGAGGGTGTTAGAAT

Downstream 100 bases:

>100_bases
AACTAAGGAGTAAATTTTTATGGATTATAATTTAATAGCCACTGCAACTTTTGGCTTAGAGGCTGTTGTTGCAAAGGAAT
TAAAAGAGTTAGGATATGAA

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MHLKASLLDENAIRRALTRLSHEIIEKNKGVEDIVLVGIKRRGYPLAERLSEFIEKFEGVKIPVASVDITLYRDDLTNVS
DTPNLNDPKIDVDIRGKKVIIVDDVLYTCRTARAAIDAIMDQGRPEFIQLAVLVDRGHKELPIRADYVGKNIPTSKDEII
KVQIKEIDGTDSVEIYEN

Sequences:

>Translated_178_residues
MHLKASLLDENAIRRALTRLSHEIIEKNKGVEDIVLVGIKRRGYPLAERLSEFIEKFEGVKIPVASVDITLYRDDLTNVS
DTPNLNDPKIDVDIRGKKVIIVDDVLYTCRTARAAIDAIMDQGRPEFIQLAVLVDRGHKELPIRADYVGKNIPTSKDEII
KVQIKEIDGTDSVEIYEN
>Mature_178_residues
MHLKASLLDENAIRRALTRLSHEIIEKNKGVEDIVLVGIKRRGYPLAERLSEFIEKFEGVKIPVASVDITLYRDDLTNVS
DTPNLNDPKIDVDIRGKKVIIVDDVLYTCRTARAAIDAIMDQGRPEFIQLAVLVDRGHKELPIRADYVGKNIPTSKDEII
KVQIKEIDGTDSVEIYEN

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_CLOP1 (Q0TPA8)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696532.1
- ProteinModelPortal:   Q0TPA8
- SMR:   Q0TPA8
- STRING:   Q0TPA8
- GeneID:   4202069
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2103
- TIGR:   CPF_2103
- eggNOG:   COG2065
- HOGENOM:   HBG641958
- OMA:   ILDITLY
- ProtClustDB:   PRK05205
- BioCyc:   CPER195103:CPF_2103-MONOMER
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 20106; Mature: 20106

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLKASLLDENAIRRALTRLSHEIIEKNKGVEDIVLVGIKRRGYPLAERLSEFIEKFEGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
KIPVASVDITLYRDDLTNVSDTPNLNDPKIDVDIRGKKVIIVDDVLYTCRTARAAIDAIM
CCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCEEEEECHHHHHHHHHHHHHHHHH
DQGRPEFIQLAVLVDRGHKELPIRADYVGKNIPTSKDEIIKVQIKEIDGTDSVEIYEN
HCCCCCCEEEEEEEECCCCCCCEEHHHCCCCCCCCCCCEEEEEEEECCCCCCEEEECC
>Mature Secondary Structure
MHLKASLLDENAIRRALTRLSHEIIEKNKGVEDIVLVGIKRRGYPLAERLSEFIEKFEGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
KIPVASVDITLYRDDLTNVSDTPNLNDPKIDVDIRGKKVIIVDDVLYTCRTARAAIDAIM
CCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCEEEEECHHHHHHHHHHHHHHHHH
DQGRPEFIQLAVLVDRGHKELPIRADYVGKNIPTSKDEIIKVQIKEIDGTDSVEIYEN
HCCCCCCEEEEEEEECCCCCCCEEHHHCCCCCCCCCCCEEEEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA