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The map label for this gene is xseA [H]

Identifier: 18310804

GI number: 18310804

Start: 2100212

End: 2101414

Strand: Reverse

Name: xseA [H]

Synonym: CPE1822

Alternate gene names: 18310804

Gene position: 2101414-2100212 (Counterclockwise)

Preceding gene: 18310805

Following gene: 18310803

Centisome position: 69.32

GC content: 27.68

Gene sequence:

>1203_bases
ATGAAACTAAAGACATTATCTGTTGGTGAAGTTAATAACTACGTTAAAAAGTTAGTTGAAAATGACTTTATATTAAAGAA
TCTTAATGTCAAAGGTGAAATATCTAATTTAAAATTCCATTCAAGTGGTCATATTTATTTTTCATTGAAAGATGAAAATA
GCAAGGTTAACTGCATTATGTTTAAAAATAATGCAGTTAATTTAGATTTTAGACTAGAAGAAGGAATGAAGGTAGAAATA
AAGGCTAGATTAGGTGTTTATCATAAAGAAGGAACTTATCAGCTTTACTGCGAAAATATTAAAAAAGCAGGAATTGGAGA
ACTTTTTGAAGAATTTCATAAATTAAAAAAAGAGCTTAGTGAAGAAGGAATTTTTGATGAAAAATACAAAAGAGCCTTAC
CAAAATTCCCTAAGAGAATTGGAATAATTACAGCAAGGACTGGAGCAGCAGTAAGGGATATAATAAACGTAATACAAAGA
AGAAATAAATCTTTAGATATTATTTTGTATCCAGCTAAGGTTCAAGGAGAAAATGCAGCAGATTCAATAATTGAGGGTAT
TAGATATTTTAATAATGAGAAATCAGTTGATGTTATCATCTTAGGTAGAGGTGGAGGATCTATTGAAGAACTTTGGGCTT
TTAATAATAGAGACTTAGCATATGAGATATTTAATAGTAGAATACCTACTGTATCAGCTGTTGGTCACGAAGTAGATTTT
ACTATTAGTGATTTTGTAAGTGATATGAGAGCACCTACACCATCAGCAGCAGGAGAGTTAGTATCACCATCATTACAAGA
AATGATAAATGATTTATTAAATAAAAAAGAGTTCTTACATAGAGCCGTTGATAGAAGATTTTTAAATGCAAAGAGAGATG
TAGATTTATTACACAAAGGATTAAAAGGTAATAATCCTACACATATAATTGAAAAAAGAATAAAAGAAGTAAATACCTTA
GAAGAAAAGTTAAACTTTTTAGGAAAAAGAAAAATTGATAAAGCAAAAGATGAACTTATTGCTTTAAATAGCATATTACA
AACCTTAAATCCATTAAACACCTTAGGAAGAGGATATTCAGTAATAATGGATAAAGAAGATAAAGTAATTAACAAAGTAA
GTGAATTAAAAAAGAACGATATGGTAAAAGTGATAATGAAGGATGGTTCCGTTAATATAGATATAAAAATTATTAATGAA
TAA

Upstream 100 bases:

>100_bases
GTTTATGACAAAGCATCATTAATTACACCAGTTCCAGGAGGCGTAGGTTCTTTAACTACGACTCTTCTTTTAAAAAATGT
TTGTAAGGAGTTAGATTAGA

Downstream 100 bases:

>100_bases
GGAGCAAAGAGAGATAAAATGGCTAGAAAAGAAACTAATTATGAAAGTATGGTTAGTGAATTAAATGAAATCGTAAAGCA
ACTGGAAAATGGAGATTTGA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKLKTLSVGEVNNYVKKLVENDFILKNLNVKGEISNLKFHSSGHIYFSLKDENSKVNCIMFKNNAVNLDFRLEEGMKVEI
KARLGVYHKEGTYQLYCENIKKAGIGELFEEFHKLKKELSEEGIFDEKYKRALPKFPKRIGIITARTGAAVRDIINVIQR
RNKSLDIILYPAKVQGENAADSIIEGIRYFNNEKSVDVIILGRGGGSIEELWAFNNRDLAYEIFNSRIPTVSAVGHEVDF
TISDFVSDMRAPTPSAAGELVSPSLQEMINDLLNKKEFLHRAVDRRFLNAKRDVDLLHKGLKGNNPTHIIEKRIKEVNTL
EEKLNFLGKRKIDKAKDELIALNSILQTLNPLNTLGRGYSVIMDKEDKVINKVSELKKNDMVKVIMKDGSVNIDIKIINE

Sequences:

>Translated_400_residues
MKLKTLSVGEVNNYVKKLVENDFILKNLNVKGEISNLKFHSSGHIYFSLKDENSKVNCIMFKNNAVNLDFRLEEGMKVEI
KARLGVYHKEGTYQLYCENIKKAGIGELFEEFHKLKKELSEEGIFDEKYKRALPKFPKRIGIITARTGAAVRDIINVIQR
RNKSLDIILYPAKVQGENAADSIIEGIRYFNNEKSVDVIILGRGGGSIEELWAFNNRDLAYEIFNSRIPTVSAVGHEVDF
TISDFVSDMRAPTPSAAGELVSPSLQEMINDLLNKKEFLHRAVDRRFLNAKRDVDLLHKGLKGNNPTHIIEKRIKEVNTL
EEKLNFLGKRKIDKAKDELIALNSILQTLNPLNTLGRGYSVIMDKEDKVINKVSELKKNDMVKVIMKDGSVNIDIKIINE
>Mature_400_residues
MKLKTLSVGEVNNYVKKLVENDFILKNLNVKGEISNLKFHSSGHIYFSLKDENSKVNCIMFKNNAVNLDFRLEEGMKVEI
KARLGVYHKEGTYQLYCENIKKAGIGELFEEFHKLKKELSEEGIFDEKYKRALPKFPKRIGIITARTGAAVRDIINVIQR
RNKSLDIILYPAKVQGENAADSIIEGIRYFNNEKSVDVIILGRGGGSIEELWAFNNRDLAYEIFNSRIPTVSAVGHEVDF
TISDFVSDMRAPTPSAAGELVSPSLQEMINDLLNKKEFLHRAVDRRFLNAKRDVDLLHKGLKGNNPTHIIEKRIKEVNTL
EEKLNFLGKRKIDKAKDELIALNSILQTLNPLNTLGRGYSVIMDKEDKVINKVSELKKNDMVKVIMKDGSVNIDIKIINE

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=439, Percent_Identity=35.3075170842825, Blast_Score=306, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 45492; Mature: 45492

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKTLSVGEVNNYVKKLVENDFILKNLNVKGEISNLKFHSSGHIYFSLKDENSKVNCIM
CCEEEECCHHHHHHHHHHHCCCCEEECCCCCEEECCEEEECCCEEEEEEECCCCEEEEEE
FKNNAVNLDFRLEEGMKVEIKARLGVYHKEGTYQLYCENIKKAGIGELFEEFHKLKKELS
EECCEEEEEEEECCCCEEEEEEEECEEECCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHH
EEGIFDEKYKRALPKFPKRIGIITARTGAAVRDIINVIQRRNKSLDIILYPAKVQGENAA
HCCCCHHHHHHHHHCCHHHHEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECEECCCCHH
DSIIEGIRYFNNEKSVDVIILGRGGGSIEELWAFNNRDLAYEIFNSRIPTVSAVGHEVDF
HHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCCCCHHHHHHHCCCCEEECCCCEECE
TISDFVSDMRAPTPSAAGELVSPSLQEMINDLLNKKEFLHRAVDRRFLNAKRDVDLLHKG
EHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
LKGNNPTHIIEKRIKEVNTLEEKLNFLGKRKIDKAKDELIALNSILQTLNPLNTLGRGYS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VIMDKEDKVINKVSELKKNDMVKVIMKDGSVNIDIKIINE
EEECCCHHHHHHHHHHHHCCEEEEEEECCCEEEEEEEECC
>Mature Secondary Structure
MKLKTLSVGEVNNYVKKLVENDFILKNLNVKGEISNLKFHSSGHIYFSLKDENSKVNCIM
CCEEEECCHHHHHHHHHHHCCCCEEECCCCCEEECCEEEECCCEEEEEEECCCCEEEEEE
FKNNAVNLDFRLEEGMKVEIKARLGVYHKEGTYQLYCENIKKAGIGELFEEFHKLKKELS
EECCEEEEEEEECCCCEEEEEEEECEEECCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHH
EEGIFDEKYKRALPKFPKRIGIITARTGAAVRDIINVIQRRNKSLDIILYPAKVQGENAA
HCCCCHHHHHHHHHCCHHHHEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECEECCCCHH
DSIIEGIRYFNNEKSVDVIILGRGGGSIEELWAFNNRDLAYEIFNSRIPTVSAVGHEVDF
HHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCCCCHHHHHHHCCCCEEECCCCEECE
TISDFVSDMRAPTPSAAGELVSPSLQEMINDLLNKKEFLHRAVDRRFLNAKRDVDLLHKG
EHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
LKGNNPTHIIEKRIKEVNTLEEKLNFLGKRKIDKAKDELIALNSILQTLNPLNTLGRGYS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VIMDKEDKVINKVSELKKNDMVKVIMKDGSVNIDIKIINE
EEECCCHHHHHHHHHHHHCCEEEEEEECCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA