Click here to switch to the map view.

The map label for this gene is frr

Identifier: 18310679

GI number: 18310679

Start: 1976070

End: 1976627

Strand: Reverse

Name: frr

Synonym: CPE1697

Alternate gene names: 18310679

Gene position: 1976627-1976070 (Counterclockwise)

Preceding gene: 18310680

Following gene: 18310678

Centisome position: 65.2

GC content: 28.32

Gene sequence:

>558_bases
ATGATTAAGGACGTTATAAAAAAATCAGAAGAAAAAATGAATAAAACTATAAATTCTTTAAATTCAGAATTAGCTACAAT
GAAAGCTGGAAGAGCTAACCCAACTATGTTAGATAGAATTCAAGTTGAGTATTATGGAAGCATGTGTCCTTTAAATCAAG
TAGCTAATGTTTCATCACCAGAACCAAGATTATTAGTTATAACACCTTGGGAAAAACCAATGCTTAAAGAAATAGAAAAA
GCTATCTTAAAATCAGATTTAGGAATAAACCCTAACAATGATGGTACTATAATAAGACTTTTAGTTCCAGAATTAACTGA
AGAAACTAGAAAAAATTTAGTTAAGAACGTTAAAAAAGTTGGAGAGCAAGCTAAGGTTGCTATAAGATCTATAAGAAAAG
ATGCAAATGATAAAGTTAAAAACTTCAAAAAAGAAGGAACTATAACTGAAGATGAAATGAAAAAGGGTGAAGATGACATC
CAAAAAGTAACAGATAAGTTTGTTAAAGAAATAGATACTATAGTGGCAGCTAAAGAAAAAGAGATTATGTCAATTTAA

Upstream 100 bases:

>100_bases
ATATTAGTATTTGCTTTAGATAATCCTGAAAACATTAAGAGAGTTGTTTTAGGAGAAAATATAGGAACAATAGTAAGCAA
AAAATAAGGAGGAGTTTTAA

Downstream 100 bases:

>100_bases
TTTAAAAAACCTGCTCTTTAGCAGGTTTTTTATTTTATAATTGAATTATAAGGAGGAACCTTCTATGTTAGATTTTTTTA
GTAAAAAAGGAAATGAAGAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIKDVIKKSEEKMNKTINSLNSELATMKAGRANPTMLDRIQVEYYGSMCPLNQVANVSSPEPRLLVITPWEKPMLKEIEK
AILKSDLGINPNNDGTIIRLLVPELTEETRKNLVKNVKKVGEQAKVAIRSIRKDANDKVKNFKKEGTITEDEMKKGEDDI
QKVTDKFVKEIDTIVAAKEKEIMSI

Sequences:

>Translated_185_residues
MIKDVIKKSEEKMNKTINSLNSELATMKAGRANPTMLDRIQVEYYGSMCPLNQVANVSSPEPRLLVITPWEKPMLKEIEK
AILKSDLGINPNNDGTIIRLLVPELTEETRKNLVKNVKKVGEQAKVAIRSIRKDANDKVKNFKKEGTITEDEMKKGEDDI
QKVTDKFVKEIDTIVAAKEKEIMSI
>Mature_185_residues
MIKDVIKKSEEKMNKTINSLNSELATMKAGRANPTMLDRIQVEYYGSMCPLNQVANVSSPEPRLLVITPWEKPMLKEIEK
AILKSDLGINPNNDGTIIRLLVPELTEETRKNLVKNVKKVGEQAKVAIRSIRKDANDKVKNFKKEGTITEDEMKKGEDDI
QKVTDKFVKEIDTIVAAKEKEIMSI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=183, Percent_Identity=31.6939890710383, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI291042689, Length=148, Percent_Identity=33.1081081081081, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=44.8648648648649, Blast_Score=174, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=25.2873563218391, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_CLOP1 (Q0TPQ6)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696384.1
- ProteinModelPortal:   Q0TPQ6
- SMR:   Q0TPQ6
- STRING:   Q0TPQ6
- GeneID:   4203579
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_1951
- TIGR:   CPF_1951
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   CPER195103:CPF_1951-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20926; Mature: 20926

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDVIKKSEEKMNKTINSLNSELATMKAGRANPTMLDRIQVEYYGSMCPLNQVANVSSP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCC
EPRLLVITPWEKPMLKEIEKAILKSDLGINPNNDGTIIRLLVPELTEETRKNLVKNVKKV
CCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
GEQAKVAIRSIRKDANDKVKNFKKEGTITEDEMKKGEDDIQKVTDKFVKEIDTIVAAKEK
HHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EIMSI
HHHCC
>Mature Secondary Structure
MIKDVIKKSEEKMNKTINSLNSELATMKAGRANPTMLDRIQVEYYGSMCPLNQVANVSSP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCC
EPRLLVITPWEKPMLKEIEKAILKSDLGINPNNDGTIIRLLVPELTEETRKNLVKNVKKV
CCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
GEQAKVAIRSIRKDANDKVKNFKKEGTITEDEMKKGEDDIQKVTDKFVKEIDTIVAAKEK
HHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
EIMSI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA