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The map label for this gene is spoIIIE

Identifier: 18310658

GI number: 18310658

Start: 1951314

End: 1953704

Strand: Reverse

Name: spoIIIE

Synonym: CPE1676

Alternate gene names: 18310658

Gene position: 1953704-1951314 (Counterclockwise)

Preceding gene: 18310659

Following gene: 18310657

Centisome position: 64.45

GC content: 31.03

Gene sequence:

>2391_bases
ATGGCTGGGGGAAAAAAGAAAACCGCAACTAAAACTCAAAAAAAGAAAAATCAAAGCCAAATTAAAGTTACAGAAGAAAT
ATATGCCTTAATAGCGATATGTGTTTCTTTAATTGTTATGTTTAGTTTATATACTGATAAAGCAGGATATTTAAGTGTTA
TATCAAGAACTCTCTTAATAGGACTTTTTGGAATAGGAGCTTTTTTTATTCCAATTTACATAATATATTTATGTACAAAG
CTTTTCTTATTTAAAAGAGAGGTGTTATTTTCAAGAATAGGATTAGGAATAACCATAGCACTTATAACTAGTGTTTTACT
TATTCAGACTGTGAATATAAACGATTATTATGTTCAGGGAAGTATATGGGGATCTATAAAAACTATATGGCATTCTCAAA
GTGAATGGCATGGAGGAGTAGTAGGATTTTTAATTGTATTACCATTATATAAATTAGTAGGTAAAATAGGACTTTTTGTT
ATTTTTGTAACTTTATATCTTATATCTTCAATGCTTATATTCGATTATAATCTAGTTTCAATAAGAAATTTCTTTGGAGG
TTTTAAGGAAAAAGCTTCTAAGGTTAAATTTGTGGATAAAAAGTATGAAAAAGATGATTATATTAATTTAAAGAAAAAAG
ATGGAGCTTCTGAAGGAAATAAAGAGAGTAAAAAAGATGATATTTCAGAGGATAACAATAAGATAAAAATATTAGACTTT
ATGAAAAATTCTTCTTTAAATGATATAGAAGATAATAAGAAGGAAAAAGATAATCAATTAAAGGATAATATTAAGATAAA
TGATTTTAAACAAGAGTCTAAAATGCCTAGAGACTTAAGTTTAGATAACACCATAATAGAGCAAAGAGGATTCAACTCAG
AAAAAGCTAAGGAAGAAGAATCTATAGATAAAGAAATATCAAATAATATAGCTAGTAAAGGCTCAAGTGTAGGGGCTAGT
TATGTTGCGCCAAATGCAGATTTATTAAATTTAAACAATAATAATGAATTAGATAAAGATGATAAAAAGGCATTATTAGC
TAATGCTGCTAAACTTGAAGAAACTCTTATGAGCTTTGGTGTAGAGGCAAAAATACTTCAAGTTACAAAAGGGCCATCTG
TTACTAGATTTGAACTTCAACCTAAGGCTGGTATAAAGGTTAGTAAAATAGTTAATTTAGCTGATGATATAGCTTTAGGA
TTAGCAGCTAAAGGGGTTAGAATAGAGGCACCTATTCCAGGAAAATCTGCCATAGGAATAGAAGTTCCAAATAAAGAGCA
AACACCAGTTTTCTTTAGAGAGATTGTAGAATCTAAAGAATTTTTAGATAACAAGTTTAAGGTAGCTTGTGCTTTAGGAA
AAGACATAACAGGTAAGGCTGTTGTTACAGATTTAAGTAAGATGCCTCACGTGCTTATTGCAGGGGCAACTGGTTCTGGT
AAGAGTGTATGCATAAACACATTAATAGTAAGTATATTATATAAGTATTCTCCAGATGAAGTTAAGCTTTTAATGATAGA
CCCAAAAGTTGTTGAATTAAATGTTTATAATGGAATTCCACACTTGCTAATTCCAGTAGTTACAGATCCTAAGAAGGCTG
CTGCGGCATTAAACTGGGCTGTAAATGAAATGACTAGAAGATATAAACTTTTTGCAGATAATGGAGTAAGAAATATAGAA
TCATATAATGCTTTATATAATAAAGGAGAAGTTCCAGAGAAGCTTCCTTATATAGTTATTATAGTAGATGAGCTTGCAGA
CCTTATGATGGCTTGTCCTCATGATGTAGAAGATTATATTTGTAGACTTGCCCAAATGGCTAGAGCCGCAGGTATGCATT
TAGTAATAGCTACTCAAAGGCCATCTGTAGATGTAATTACAGGGGTAATTAAGGCTAATATACCTTCTAGAATATCCTTT
GCAGTTTCAAGCCAAATTGACTCTAGAACAATACTAGATTCAGCAGGAGCTGAAAAACTTTTAGGTAGGGGAGATATGTT
ATTCTACCCAGTTGGAGAGTCTAAGCCTCAAAGAGTTCAAGGAGCCTTTATTTCAGAGGAAGAAGTTGAACATGTTGTAT
CCTTTATAAAAGAGTCACAAAGGGATGCTCAGTATGAAGAAGATATATTAGAACATATAAACTCAGCAACTATTGCTTCA
GAGGGAAATGGTGATGGTGATAGGGATGAACTTTTAGATGAAGCTATAGAAATCGTAGTTGAAAGTGGTCAAGCTTCAGC
ATCATATTTACAAAGAAGATTAAGAATAGGATTTAATAGAGCGGCAAGAATAATAGAAGAGCTAGAAGAATGTGGTGTTA
TTTCTAGAAGAGATGGAAGTAAACCAAGACAAGTACTTCTTAGTAAAGATGAATTAGAAAATATGAAATAA

Upstream 100 bases:

>100_bases
AATATTTTGACAATTTATAGTCATTTATGTATATAATATTTTTTGGTACAAGTATTTTACCATTTTGAAATTAAAATAGG
GTGAGGTGATTTAGTTTAGT

Downstream 100 bases:

>100_bases
AAACTTGTTTAATTTAAAAAAGAGTTTTAAAATAAGAAATATATATTTAAACGTAGGAGGAAGTAGATTTGGCGAAATAT
AAGGTAGGAATGGTGAGTTT

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 796; Mature: 795

Protein sequence:

>796_residues
MAGGKKKTATKTQKKKNQSQIKVTEEIYALIAICVSLIVMFSLYTDKAGYLSVISRTLLIGLFGIGAFFIPIYIIYLCTK
LFLFKREVLFSRIGLGITIALITSVLLIQTVNINDYYVQGSIWGSIKTIWHSQSEWHGGVVGFLIVLPLYKLVGKIGLFV
IFVTLYLISSMLIFDYNLVSIRNFFGGFKEKASKVKFVDKKYEKDDYINLKKKDGASEGNKESKKDDISEDNNKIKILDF
MKNSSLNDIEDNKKEKDNQLKDNIKINDFKQESKMPRDLSLDNTIIEQRGFNSEKAKEEESIDKEISNNIASKGSSVGAS
YVAPNADLLNLNNNNELDKDDKKALLANAAKLEETLMSFGVEAKILQVTKGPSVTRFELQPKAGIKVSKIVNLADDIALG
LAAKGVRIEAPIPGKSAIGIEVPNKEQTPVFFREIVESKEFLDNKFKVACALGKDITGKAVVTDLSKMPHVLIAGATGSG
KSVCINTLIVSILYKYSPDEVKLLMIDPKVVELNVYNGIPHLLIPVVTDPKKAAAALNWAVNEMTRRYKLFADNGVRNIE
SYNALYNKGEVPEKLPYIVIIVDELADLMMACPHDVEDYICRLAQMARAAGMHLVIATQRPSVDVITGVIKANIPSRISF
AVSSQIDSRTILDSAGAEKLLGRGDMLFYPVGESKPQRVQGAFISEEEVEHVVSFIKESQRDAQYEEDILEHINSATIAS
EGNGDGDRDELLDEAIEIVVESGQASASYLQRRLRIGFNRAARIIEELEECGVISRRDGSKPRQVLLSKDELENMK

Sequences:

>Translated_796_residues
MAGGKKKTATKTQKKKNQSQIKVTEEIYALIAICVSLIVMFSLYTDKAGYLSVISRTLLIGLFGIGAFFIPIYIIYLCTK
LFLFKREVLFSRIGLGITIALITSVLLIQTVNINDYYVQGSIWGSIKTIWHSQSEWHGGVVGFLIVLPLYKLVGKIGLFV
IFVTLYLISSMLIFDYNLVSIRNFFGGFKEKASKVKFVDKKYEKDDYINLKKKDGASEGNKESKKDDISEDNNKIKILDF
MKNSSLNDIEDNKKEKDNQLKDNIKINDFKQESKMPRDLSLDNTIIEQRGFNSEKAKEEESIDKEISNNIASKGSSVGAS
YVAPNADLLNLNNNNELDKDDKKALLANAAKLEETLMSFGVEAKILQVTKGPSVTRFELQPKAGIKVSKIVNLADDIALG
LAAKGVRIEAPIPGKSAIGIEVPNKEQTPVFFREIVESKEFLDNKFKVACALGKDITGKAVVTDLSKMPHVLIAGATGSG
KSVCINTLIVSILYKYSPDEVKLLMIDPKVVELNVYNGIPHLLIPVVTDPKKAAAALNWAVNEMTRRYKLFADNGVRNIE
SYNALYNKGEVPEKLPYIVIIVDELADLMMACPHDVEDYICRLAQMARAAGMHLVIATQRPSVDVITGVIKANIPSRISF
AVSSQIDSRTILDSAGAEKLLGRGDMLFYPVGESKPQRVQGAFISEEEVEHVVSFIKESQRDAQYEEDILEHINSATIAS
EGNGDGDRDELLDEAIEIVVESGQASASYLQRRLRIGFNRAARIIEELEECGVISRRDGSKPRQVLLSKDELENMK
>Mature_795_residues
AGGKKKTATKTQKKKNQSQIKVTEEIYALIAICVSLIVMFSLYTDKAGYLSVISRTLLIGLFGIGAFFIPIYIIYLCTKL
FLFKREVLFSRIGLGITIALITSVLLIQTVNINDYYVQGSIWGSIKTIWHSQSEWHGGVVGFLIVLPLYKLVGKIGLFVI
FVTLYLISSMLIFDYNLVSIRNFFGGFKEKASKVKFVDKKYEKDDYINLKKKDGASEGNKESKKDDISEDNNKIKILDFM
KNSSLNDIEDNKKEKDNQLKDNIKINDFKQESKMPRDLSLDNTIIEQRGFNSEKAKEEESIDKEISNNIASKGSSVGASY
VAPNADLLNLNNNNELDKDDKKALLANAAKLEETLMSFGVEAKILQVTKGPSVTRFELQPKAGIKVSKIVNLADDIALGL
AAKGVRIEAPIPGKSAIGIEVPNKEQTPVFFREIVESKEFLDNKFKVACALGKDITGKAVVTDLSKMPHVLIAGATGSGK
SVCINTLIVSILYKYSPDEVKLLMIDPKVVELNVYNGIPHLLIPVVTDPKKAAAALNWAVNEMTRRYKLFADNGVRNIES
YNALYNKGEVPEKLPYIVIIVDELADLMMACPHDVEDYICRLAQMARAAGMHLVIATQRPSVDVITGVIKANIPSRISFA
VSSQIDSRTILDSAGAEKLLGRGDMLFYPVGESKPQRVQGAFISEEEVEHVVSFIKESQRDAQYEEDILEHINSATIASE
GNGDGDRDELLDEAIEIVVESGQASASYLQRRLRIGFNRAARIIEELEECGVISRRDGSKPRQVLLSKDELENMK

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=485, Percent_Identity=48.659793814433, Blast_Score=434, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_CLOPE (Q8XJS8)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_562592.1
- ProteinModelPortal:   Q8XJS8
- SMR:   Q8XJS8
- GeneID:   989986
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE1676
- NMPDR:   fig|195102.1.peg.1739
- HOGENOM:   HBG662140
- OMA:   AAALNWA
- ProtClustDB:   CLSK882943
- BioCyc:   CPER195102:CPE1676-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 88368; Mature: 88237

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xec5f564)-; HASH(0xf57957c)-; HASH(0xea03424)-; HASH(0xe704644)-; HASH(0xf39647c)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGGKKKTATKTQKKKNQSQIKVTEEIYALIAICVSLIVMFSLYTDKAGYLSVISRTLLI
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GLFGIGAFFIPIYIIYLCTKLFLFKREVLFSRIGLGITIALITSVLLIQTVNINDYYVQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECCCEEEEEE
SIWGSIKTIWHSQSEWHGGVVGFLIVLPLYKLVGKIGLFVIFVTLYLISSMLIFDYNLVS
EECHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IRNFFGGFKEKASKVKFVDKKYEKDDYINLKKKDGASEGNKESKKDDISEDNNKIKILDF
HHHHHCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEE
MKNSSLNDIEDNKKEKDNQLKDNIKINDFKQESKMPRDLSLDNTIIEQRGFNSEKAKEEE
ECCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHH
SIDKEISNNIASKGSSVGASYVAPNADLLNLNNNNELDKDDKKALLANAAKLEETLMSFG
HHHHHHHHHHHHCCCCCCCHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
VEAKILQVTKGPSVTRFELQPKAGIKVSKIVNLADDIALGLAAKGVRIEAPIPGKSAIGI
CCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEE
EVPNKEQTPVFFREIVESKEFLDNKFKVACALGKDITGKAVVTDLSKMPHVLIAGATGSG
ECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCC
KSVCINTLIVSILYKYSPDEVKLLMIDPKVVELNVYNGIPHLLIPVVTDPKKAAAALNWA
CHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHH
VNEMTRRYKLFADNGVRNIESYNALYNKGEVPEKLPYIVIIVDELADLMMACPHDVEDYI
HHHHHHHHHHEECCCCHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHCCCCHHHHH
CRLAQMARAAGMHLVIATQRPSVDVITGVIKANIPSRISFAVSSQIDSRTILDSAGAEKL
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEHHHHCCCCCHHHHHHCCHHHH
LGRGDMLFYPVGESKPQRVQGAFISEEEVEHVVSFIKESQRDAQYEEDILEHINSATIAS
HCCCCEEEEECCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEC
EGNGDGDRDELLDEAIEIVVESGQASASYLQRRLRIGFNRAARIIEELEECGVISRRDGS
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEECCCCC
KPRQVLLSKDELENMK
CHHHHHCCHHHHCCCH
>Mature Secondary Structure 
AGGKKKTATKTQKKKNQSQIKVTEEIYALIAICVSLIVMFSLYTDKAGYLSVISRTLLI
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GLFGIGAFFIPIYIIYLCTKLFLFKREVLFSRIGLGITIALITSVLLIQTVNINDYYVQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECCCEEEEEE
SIWGSIKTIWHSQSEWHGGVVGFLIVLPLYKLVGKIGLFVIFVTLYLISSMLIFDYNLVS
EECHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IRNFFGGFKEKASKVKFVDKKYEKDDYINLKKKDGASEGNKESKKDDISEDNNKIKILDF
HHHHHCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEE
MKNSSLNDIEDNKKEKDNQLKDNIKINDFKQESKMPRDLSLDNTIIEQRGFNSEKAKEEE
ECCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHH
SIDKEISNNIASKGSSVGASYVAPNADLLNLNNNNELDKDDKKALLANAAKLEETLMSFG
HHHHHHHHHHHHCCCCCCCHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
VEAKILQVTKGPSVTRFELQPKAGIKVSKIVNLADDIALGLAAKGVRIEAPIPGKSAIGI
CCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEE
EVPNKEQTPVFFREIVESKEFLDNKFKVACALGKDITGKAVVTDLSKMPHVLIAGATGSG
ECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCC
KSVCINTLIVSILYKYSPDEVKLLMIDPKVVELNVYNGIPHLLIPVVTDPKKAAAALNWA
CHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHH
VNEMTRRYKLFADNGVRNIESYNALYNKGEVPEKLPYIVIIVDELADLMMACPHDVEDYI
HHHHHHHHHHEECCCCHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHCCCCHHHHH
CRLAQMARAAGMHLVIATQRPSVDVITGVIKANIPSRISFAVSSQIDSRTILDSAGAEKL
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEHHHHCCCCCHHHHHHCCHHHH
LGRGDMLFYPVGESKPQRVQGAFISEEEVEHVVSFIKESQRDAQYEEDILEHINSATIAS
HCCCCEEEEECCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEC
EGNGDGDRDELLDEAIEIVVESGQASASYLQRRLRIGFNRAARIIEELEECGVISRRDGS
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEECCCCC
KPRQVLLSKDELENMK
CHHHHHCCHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11792842