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The map label for this gene is pgsA [H]

Identifier: 18310656

GI number: 18310656

Start: 1949334

End: 1949924

Strand: Reverse

Name: pgsA [H]

Synonym: CPE1674

Alternate gene names: 18310656

Gene position: 1949924-1949334 (Counterclockwise)

Preceding gene: 18310657

Following gene: 18310655

Centisome position: 64.32

GC content: 29.95

Gene sequence:

>591_bases
ATGAATCTTGCAAATAAATTAACTTTAATTAGAATAATTTTAGTGCCCATATTCTTAGTATTTATAGCTTACCAAGACTT
ACCTTATGGGAGTGTAATAGCAACACTTATATTCATAATAGCATCTGTTACAGATCAATTAGATGGATATATTGCAAGAT
CAAGAAATCAAGTAACTAACTTTGGTAAGTTTATGGACCCTTTGGCAGATAAGCTACTAGTTACAGCAGCACTTATATCT
TTGGTTGAATTACAATTAGTTCCTGCATGGGCAGCTATTGTAATAATAGCTAGAGAGTTTGCTGTTTCAGGTTTAAGAAC
CATAGCTGCATCAGAGGGGTTAGTTATAGCTGCTAGCTGGTGGGGAAAAATTAAAACTGTAATACAAATAATTGCCATAG
TGCTTTTATTATTACAAGTAAATATAATTAATTCACCAGGGATTAAGGAATTAGTTGCAGGCAGCAGCTTTTTAAGAAAT
TTCTTTATATATGTTCCAGATATATTCTTATATTTAGCTGTTGCAATAACAATAATTTCTGGAGTAGATTACTTTAGAAA
AAATAAAAATGTTATAAATACTTATAAATAA

Upstream 100 bases:

>100_bases
GGATGTATTTATGTGAAAGGAAATGGAGCTAAAAAGGACCAGTTCTGTAAAGTTAAAATTGAAAAGGCCTTAGAATATGA
TTTGGTAGGAGTTGTATGCA

Downstream 100 bases:

>100_bases
TGTTTTAAAAGTCAAAAAATAGTCAATTATTAAGACATGAGGTTCTTTTAAGAACTTCATGTTGATGTTGACTTTTTTTT
TGTATATATTATAATAATAG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MNLANKLTLIRIILVPIFLVFIAYQDLPYGSVIATLIFIIASVTDQLDGYIARSRNQVTNFGKFMDPLADKLLVTAALIS
LVELQLVPAWAAIVIIAREFAVSGLRTIAASEGLVIAASWWGKIKTVIQIIAIVLLLLQVNIINSPGIKELVAGSSFLRN
FFIYVPDIFLYLAVAITIISGVDYFRKNKNVINTYK

Sequences:

>Translated_196_residues
MNLANKLTLIRIILVPIFLVFIAYQDLPYGSVIATLIFIIASVTDQLDGYIARSRNQVTNFGKFMDPLADKLLVTAALIS
LVELQLVPAWAAIVIIAREFAVSGLRTIAASEGLVIAASWWGKIKTVIQIIAIVLLLLQVNIINSPGIKELVAGSSFLRN
FFIYVPDIFLYLAVAITIISGVDYFRKNKNVINTYK
>Mature_196_residues
MNLANKLTLIRIILVPIFLVFIAYQDLPYGSVIATLIFIIASVTDQLDGYIARSRNQVTNFGKFMDPLADKLLVTAALIS
LVELQLVPAWAAIVIIAREFAVSGLRTIAASEGLVIAASWWGKIKTVIQIIAIVLLLLQVNIINSPGIKELVAGSSFLRN
FFIYVPDIFLYLAVAITIISGVDYFRKNKNVINTYK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=146, Percent_Identity=43.1506849315069, Blast_Score=103, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24650130, Length=100, Percent_Identity=39, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24650126, Length=100, Percent_Identity=39, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24650128, Length=100, Percent_Identity=39, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21643; Mature: 21643

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLANKLTLIRIILVPIFLVFIAYQDLPYGSVIATLIFIIASVTDQLDGYIARSRNQVTN
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGKFMDPLADKLLVTAALISLVELQLVPAWAAIVIIAREFAVSGLRTIAASEGLVIAASW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHH
WGKIKTVIQIIAIVLLLLQVNIINSPGIKELVAGSSFLRNFFIYVPDIFLYLAVAITIIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVDYFRKNKNVINTYK
HHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNLANKLTLIRIILVPIFLVFIAYQDLPYGSVIATLIFIIASVTDQLDGYIARSRNQVTN
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGKFMDPLADKLLVTAALISLVELQLVPAWAAIVIIAREFAVSGLRTIAASEGLVIAASW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHH
WGKIKTVIQIIAIVLLLLQVNIINSPGIKELVAGSSFLRNFFIYVPDIFLYLAVAITIIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVDYFRKNKNVINTYK
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]