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The map label for this gene is thiE [H]

Identifier: 18310581

GI number: 18310581

Start: 1872446

End: 1873027

Strand: Reverse

Name: thiE [H]

Synonym: CPE1599

Alternate gene names: 18310581

Gene position: 1873027-1872446 (Counterclockwise)

Preceding gene: 18310582

Following gene: 18310580

Centisome position: 61.79

GC content: 28.69

Gene sequence:

>582_bases
ATGTTTTTAATAACCAATAGAAAGTTAGTAAATAGGGAAAGATATTTTAATACTATAGAGGAAGCAGGTAAATATGGTGT
TAAAAATATAATTTTAAGAGAAAAAGATTTAAGTACAGAGGAATTAATAGAGGTTTATATAAAAATAAAAGAGTTAGTTC
CAGAGGAAACAAATATAATAATAAATTCTAATATTGAAGCAACAAGGATTTTGAAAGAGAAGTTTATTCATTTAAGCTTT
AAGGATTTTAAGAAGAATTTAGAAGAAGTTAAATCCTTACAGGTTGGAGTATCTGTTCACTCTATCTTAGAGGCCATTGA
GGCTGATAGATTAGGGGCAAGCTATATATTAGTATCTCCTATTTTTGAAACGCAATGTAAGAAGGGCGTAACTCCTAAGG
GAATTAATTTTATAAAAGAGATTAAGGAAAAGGTAAATTGCAAGGTCATAGCCTTAGGAGGAATAAATGAACATAACTTT
AAAGAAGTATTAGGGGCTGGCGCTGATGATTTTGCATGTATGTCACTTTTATTTATGAGTAATAATATAAAGAAGTCCTT
AGATACTTTTAAAGCTCTTTAA

Upstream 100 bases:

>100_bases
TAAGTGAAGTTAAGGAATTAATAAAAAGTCAAGGTTATCAACCTATATTTAAGGATTGGCATAGATTTTAAAATAATTTT
TTATTAAAATGGTGATTTTT

Downstream 100 bases:

>100_bases
ATATATCTAGATTTATATGAAGGAAAATGTAAATTATATGATTATTAATAGAATTATGATATAATTGATATTAATTAATA
ATTACAATTTGTTATCAAAG

Product: thiamine monophosphate synthase family protein

Products: NA

Alternate protein names: TMP pyrophosphorylase; TMP-PPase; Thiamine-phosphate synthase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MFLITNRKLVNRERYFNTIEEAGKYGVKNIILREKDLSTEELIEVYIKIKELVPEETNIIINSNIEATRILKEKFIHLSF
KDFKKNLEEVKSLQVGVSVHSILEAIEADRLGASYILVSPIFETQCKKGVTPKGINFIKEIKEKVNCKVIALGGINEHNF
KEVLGAGADDFACMSLLFMSNNIKKSLDTFKAL

Sequences:

>Translated_193_residues
MFLITNRKLVNRERYFNTIEEAGKYGVKNIILREKDLSTEELIEVYIKIKELVPEETNIIINSNIEATRILKEKFIHLSF
KDFKKNLEEVKSLQVGVSVHSILEAIEADRLGASYILVSPIFETQCKKGVTPKGINFIKEIKEKVNCKVIALGGINEHNF
KEVLGAGADDFACMSLLFMSNNIKKSLDTFKAL
>Mature_193_residues
MFLITNRKLVNRERYFNTIEEAGKYGVKNIILREKDLSTEELIEVYIKIKELVPEETNIIINSNIEATRILKEKFIHLSF
KDFKKNLEEVKSLQVGVSVHSILEAIEADRLGASYILVSPIFETQCKKGVTPKGINFIKEIKEKVNCKVIALGGINEHNF
KEVLGAGADDFACMSLLFMSNNIKKSLDTFKAL

Specific function: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) [H]

COG id: COG0352

COG function: function code H; Thiamine monophosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TMP-PPase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022998
- InterPro:   IPR003733 [H]

Pfam domain/function: PF02581 TMP-TENI [H]

EC number: =2.5.1.3 [H]

Molecular weight: Translated: 21926; Mature: 21926

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLITNRKLVNRERYFNTIEEAGKYGVKNIILREKDLSTEELIEVYIKIKELVPEETNII
CEEECCHHHHHHHHHHHHHHHHHHHCHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCEE
INSNIEATRILKEKFIHLSFKDFKKNLEEVKSLQVGVSVHSILEAIEADRLGASYILVSP
EECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECH
IFETQCKKGVTPKGINFIKEIKEKVNCKVIALGGINEHNFKEVLGAGADDFACMSLLFMS
HHHHHHHCCCCCCHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHH
NNIKKSLDTFKAL
CCHHHHHHHHHCC
>Mature Secondary Structure
MFLITNRKLVNRERYFNTIEEAGKYGVKNIILREKDLSTEELIEVYIKIKELVPEETNII
CEEECCHHHHHHHHHHHHHHHHHHHCHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCEE
INSNIEATRILKEKFIHLSFKDFKKNLEEVKSLQVGVSVHSILEAIEADRLGASYILVSP
EECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECH
IFETQCKKGVTPKGINFIKEIKEKVNCKVIALGGINEHNFKEVLGAGADDFACMSLLFMS
HHHHHHHCCCCCCHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHH
NNIKKSLDTFKAL
CCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]