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The map label for this gene is uppS [H]

Identifier: 18310540

GI number: 18310540

Start: 1827243

End: 1827884

Strand: Direct

Name: uppS [H]

Synonym: CPE1558

Alternate gene names: 18310540

Gene position: 1827243-1827884 (Clockwise)

Preceding gene: 18310535

Following gene: 18310541

Centisome position: 60.28

GC content: 31.93

Gene sequence:

>642_bases
ATGAGAATTCCAAAACATATAGGGGTTATCCCAGATGGCAATAGACGTTGGGCTGTAGAAAATGGACTTGAAAAAGATCA
AGGATATTTACATGGAATTGAACCTGGACTTGAACTTTTTAAACTTTGTCAAAAACTAGATATTAAAGAAATAACTTATT
ATGGTTTTACTACAGACAATACGAAAAGACCATCATATCAAAAAAAGGCATTCATAGATGCCTGCATAAAATCAGTAGAG
TTAATTGCAAATGAAGATTGTGAATTGCTTGTTATAGGGAATGCTGATTCTCCAGTTTTTCCTGAAGAGTTAAAAAAATA
TACTAAAAGGACTAAAATGGGTAAAGGTGGCATACGCGTTAACTTCCTTGTTAACTATGGTTGGGAATGGGATTTAAACC
TTCTAAAAGCCTGTGACATTAAGAGTAAAAATATCTATGATAATATTCAATCAAAGGATATTTCAAGAATAGATTTATTA
ATAAGATGGGGCGGTAGACGTAGATTAAGCGGATTTTTGCCAGTTCAATCAGTTTATTCTGATATATACATAATTGATGA
TTTATGGCCTAATTTTAATAAAGATCATTTCTTTAATGCTCTTGAATGGTACAACGATCAAGATATTACCCTAGGCGGTT
AA

Upstream 100 bases:

>100_bases
ATATAATTAAAATTTAAAATAATCAAATTTATGCATTTTATTTATTAAAATGGGAATACTTTCATTTGAAGCTATTTTTA
AGAAAGGGTTGAGACATATT

Downstream 100 bases:

>100_bases
TTAAATGAGTTCAAAGAAAAAAGCTATAATAGTTGGAGCTGGAATAGGTGGATTAGCTACTGCTGTTCGCCTTCTTGTTA
ATAATTTTGAAGTAGATATT

Product: di-trans, poly-cis-decaprenylcistransferase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MRIPKHIGVIPDGNRRWAVENGLEKDQGYLHGIEPGLELFKLCQKLDIKEITYYGFTTDNTKRPSYQKKAFIDACIKSVE
LIANEDCELLVIGNADSPVFPEELKKYTKRTKMGKGGIRVNFLVNYGWEWDLNLLKACDIKSKNIYDNIQSKDISRIDLL
IRWGGRRRLSGFLPVQSVYSDIYIIDDLWPNFNKDHFFNALEWYNDQDITLGG

Sequences:

>Translated_213_residues
MRIPKHIGVIPDGNRRWAVENGLEKDQGYLHGIEPGLELFKLCQKLDIKEITYYGFTTDNTKRPSYQKKAFIDACIKSVE
LIANEDCELLVIGNADSPVFPEELKKYTKRTKMGKGGIRVNFLVNYGWEWDLNLLKACDIKSKNIYDNIQSKDISRIDLL
IRWGGRRRLSGFLPVQSVYSDIYIIDDLWPNFNKDHFFNALEWYNDQDITLGG
>Mature_213_residues
MRIPKHIGVIPDGNRRWAVENGLEKDQGYLHGIEPGLELFKLCQKLDIKEITYYGFTTDNTKRPSYQKKAFIDACIKSVE
LIANEDCELLVIGNADSPVFPEELKKYTKRTKMGKGGIRVNFLVNYGWEWDLNLLKACDIKSKNIYDNIQSKDISRIDLL
IRWGGRRRLSGFLPVQSVYSDIYIIDDLWPNFNKDHFFNALEWYNDQDITLGG

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580738, Length=226, Percent_Identity=25.6637168141593, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI45580742, Length=226, Percent_Identity=25.6637168141593, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1786371, Length=229, Percent_Identity=26.6375545851528, Blast_Score=99, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319474, Length=210, Percent_Identity=25.2380952380952, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323748, Length=245, Percent_Identity=23.265306122449, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI18857969, Length=225, Percent_Identity=23.5555555555556, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 24700; Mature: 24700

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIPKHIGVIPDGNRRWAVENGLEKDQGYLHGIEPGLELFKLCQKLDIKEITYYGFTTDN
CCCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEEEEEECCC
TKRPSYQKKAFIDACIKSVELIANEDCELLVIGNADSPVFPEELKKYTKRTKMGKGGIRV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEE
NFLVNYGWEWDLNLLKACDIKSKNIYDNIQSKDISRIDLLIRWGGRRRLSGFLPVQSVYS
EEEEECCCEECCHHHEECCCCCCCHHHCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHC
DIYIIDDLWPNFNKDHFFNALEWYNDQDITLGG
CEEEEECCCCCCCHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MRIPKHIGVIPDGNRRWAVENGLEKDQGYLHGIEPGLELFKLCQKLDIKEITYYGFTTDN
CCCCCCCCCCCCCCCEEEECCCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEEEEEECCC
TKRPSYQKKAFIDACIKSVELIANEDCELLVIGNADSPVFPEELKKYTKRTKMGKGGIRV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEE
NFLVNYGWEWDLNLLKACDIKSKNIYDNIQSKDISRIDLLIRWGGRRRLSGFLPVQSVYS
EEEEECCCEECCHHHEECCCCCCCHHHCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHC
DIYIIDDLWPNFNKDHFFNALEWYNDQDITLGG
CEEEEECCCCCCCHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA