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The map label for this gene is clpX

Identifier: 18310374

GI number: 18310374

Start: 1642974

End: 1644281

Strand: Reverse

Name: clpX

Synonym: CPE1392

Alternate gene names: 18310374

Gene position: 1644281-1642974 (Counterclockwise)

Preceding gene: 18310375

Following gene: 18310373

Centisome position: 54.24

GC content: 31.35

Gene sequence:

>1308_bases
ATGGGAAAATTTGAAGACAAAAAGCAATTAAGATGTTCTTTTTGTGGTAAAAATCAGGAACAGGTTAAGAGATTAATCGC
AGGTCCTGGTGTATATATATGTGATGAATGTATAGAGCTTTGTTCAGAAATAATAGAAGATGAATTTGAAGGAAATACAG
AATCATCACCATTAGAAGCTAGCAATCTTCCAAAGCCACAAGAAATCAAAGACTATTTAGATCAATATGTTGTTGGTCAA
GATAGAGCTAAGAAATCTTTAGCAGTAGCTGTTTATAATCATTACAAGAGAATAAATGCTAATAAGGCAGAGGATGATGT
TGAATTACAAAAAAGTAACATACTTTTATTAGGACCTACAGGTTCAGGTAAGACATTACTTGCGCAAACACTTGCTAAAA
TGTTAAATGTTCCATTTGCTATAGCAGATGCTACAACATTAACAGAGGCAGGATATGTTGGTGAAGATGTTGAAAATATA
CTTTTAAAGCTAATTCAAAATGCAGATTATGATGTTGAAAGAGCTGAAAAAGGTATAATATATATAGATGAGATAGATAA
GATTGCTAGAAAATCAGAAAATCCATCTATTACAAGAGATGTTTCTGGAGAGGGTGTTCAACAAGCCTTATTAAAAATAT
TAGAGGGAACAACAGCTTCAGTACCACCACAAGGTGGAAGAAAGCATCCACATCAAGAGTTTATACAAATTAATACTTCA
AATATTTTATTTATTTGTGGTGGAGCTTTTGATGGAATAGATAAAATAATAGAAAAAAGAGGAACTAAGAGTTCTATAGG
TTTTGGCGCTGAGGTTAAAGGAAAAAGCGAAAAGAACGTTGGAGAACTTTTAAAGGATATAATGCCTGGGGATTTATTAA
AATTTGGTTTAATACCAGAATTTGTTGGTAGATTACCAGTATTAGTAACTTTAGAAGCTTTAGATAACGAAGCTTTAGTA
AGTATTTTAACTAAGCCAAAGAATGCTCTAGTAAAACAATACAAAAAGTTATTTGAGCTTGATAATGTAAAACTAGATTT
TACAGAGGAAGCTTTAAAAGCTATTGCAGATGAAGCTATAAATAGAAAAACTGGTGCTAGAGGATTAAGAGCTATAGTAG
AAGAAACTATGATGGATATAATGTTTGATATACCATCAGAAGAGAATATTGTAAAAGCTACTATAACTGAAGAGACAATA
AAAGATAGAAAAGATCCAGAGCTTGAAAAGCTTCCAGAAGGAGAAGTTAGACCAACTTTAAAAACTGAGAAGAAAAATAA
AGCTAGAAAAGATATAGAAACTGCTTAA

Upstream 100 bases:

>100_bases
CATGGAAGCATCAGAAGCAGTAGAATACGGATTAATAGATAAAGTTATAGAAAGAAAATAATCTACAACTTAAATCTTAT
TGAAAGTTGAGGTGGATAAG

Downstream 100 bases:

>100_bases
TAGAAAAAGATGCATACTATTTATGCATCTTTTTTATTTTTTATGGAGTTTTTGGAATATCATCACAAAAATAGGTAAAT
ACTAACCGTATAGAACGGGA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MGKFEDKKQLRCSFCGKNQEQVKRLIAGPGVYICDECIELCSEIIEDEFEGNTESSPLEASNLPKPQEIKDYLDQYVVGQ
DRAKKSLAVAVYNHYKRINANKAEDDVELQKSNILLLGPTGSGKTLLAQTLAKMLNVPFAIADATTLTEAGYVGEDVENI
LLKLIQNADYDVERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQINTS
NILFICGGAFDGIDKIIEKRGTKSSIGFGAEVKGKSEKNVGELLKDIMPGDLLKFGLIPEFVGRLPVLVTLEALDNEALV
SILTKPKNALVKQYKKLFELDNVKLDFTEEALKAIADEAINRKTGARGLRAIVEETMMDIMFDIPSEENIVKATITEETI
KDRKDPELEKLPEGEVRPTLKTEKKNKARKDIETA

Sequences:

>Translated_435_residues
MGKFEDKKQLRCSFCGKNQEQVKRLIAGPGVYICDECIELCSEIIEDEFEGNTESSPLEASNLPKPQEIKDYLDQYVVGQ
DRAKKSLAVAVYNHYKRINANKAEDDVELQKSNILLLGPTGSGKTLLAQTLAKMLNVPFAIADATTLTEAGYVGEDVENI
LLKLIQNADYDVERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQINTS
NILFICGGAFDGIDKIIEKRGTKSSIGFGAEVKGKSEKNVGELLKDIMPGDLLKFGLIPEFVGRLPVLVTLEALDNEALV
SILTKPKNALVKQYKKLFELDNVKLDFTEEALKAIADEAINRKTGARGLRAIVEETMMDIMFDIPSEENIVKATITEETI
KDRKDPELEKLPEGEVRPTLKTEKKNKARKDIETA
>Mature_434_residues
GKFEDKKQLRCSFCGKNQEQVKRLIAGPGVYICDECIELCSEIIEDEFEGNTESSPLEASNLPKPQEIKDYLDQYVVGQD
RAKKSLAVAVYNHYKRINANKAEDDVELQKSNILLLGPTGSGKTLLAQTLAKMLNVPFAIADATTLTEAGYVGEDVENIL
LKLIQNADYDVERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQINTSN
ILFICGGAFDGIDKIIEKRGTKSSIGFGAEVKGKSEKNVGELLKDIMPGDLLKFGLIPEFVGRLPVLVTLEALDNEALVS
ILTKPKNALVKQYKKLFELDNVKLDFTEEALKAIADEAINRKTGARGLRAIVEETMMDIMFDIPSEENIVKATITEETIK
DRKDPELEKLPEGEVRPTLKTEKKNKARKDIETA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=339, Percent_Identity=49.5575221238938, Blast_Score=321, Evalue=8e-88,
Organism=Escherichia coli, GI1786642, Length=404, Percent_Identity=64.6039603960396, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=45.6310679611651, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=320, Percent_Identity=45.3125, Blast_Score=277, Evalue=8e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=320, Percent_Identity=45.3125, Blast_Score=277, Evalue=8e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=409, Percent_Identity=39.3643031784841, Blast_Score=265, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=40, Blast_Score=171, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=433, Percent_Identity=39.4919168591224, Blast_Score=278, Evalue=9e-76,
Organism=Drosophila melanogaster, GI24648291, Length=327, Percent_Identity=47.4006116207951, Blast_Score=305, Evalue=5e-83,
Organism=Drosophila melanogaster, GI24648289, Length=327, Percent_Identity=47.4006116207951, Blast_Score=305, Evalue=5e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_CLOP1 (Q0TQK3)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696087.1
- ProteinModelPortal:   Q0TQK3
- STRING:   Q0TQK3
- GeneID:   4201971
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_1646
- TIGR:   CPF_1646
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   CPER195103:CPF_1646-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 48179; Mature: 48048

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFEDKKQLRCSFCGKNQEQVKRLIAGPGVYICDECIELCSEIIEDEFEGNTESSPLEA
CCCCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SNLPKPQEIKDYLDQYVVGQDRAKKSLAVAVYNHYKRINANKAEDDVELQKSNILLLGPT
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEECCCEEEECCC
GSGKTLLAQTLAKMLNVPFAIADATTLTEAGYVGEDVENILLKLIQNADYDVERAEKGII
CCCHHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCCCEE
YIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQINTS
EEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEECCC
NILFICGGAFDGIDKIIEKRGTKSSIGFGAEVKGKSEKNVGELLKDIMPGDLLKFGLIPE
CEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
FVGRLPVLVTLEALDNEALVSILTKPKNALVKQYKKLFELDNVKLDFTEEALKAIADEAI
HHCCCCEEEEHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHH
NRKTGARGLRAIVEETMMDIMFDIPSEENIVKATITEETIKDRKDPELEKLPEGEVRPTL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHCCCCCCHHHCCCCCCCCCC
KTEKKNKARKDIETA
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
GKFEDKKQLRCSFCGKNQEQVKRLIAGPGVYICDECIELCSEIIEDEFEGNTESSPLEA
CCCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SNLPKPQEIKDYLDQYVVGQDRAKKSLAVAVYNHYKRINANKAEDDVELQKSNILLLGPT
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEECCCEEEECCC
GSGKTLLAQTLAKMLNVPFAIADATTLTEAGYVGEDVENILLKLIQNADYDVERAEKGII
CCCHHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCCCEE
YIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQINTS
EEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEECCC
NILFICGGAFDGIDKIIEKRGTKSSIGFGAEVKGKSEKNVGELLKDIMPGDLLKFGLIPE
CEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
FVGRLPVLVTLEALDNEALVSILTKPKNALVKQYKKLFELDNVKLDFTEEALKAIADEAI
HHCCCCEEEEHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHH
NRKTGARGLRAIVEETMMDIMFDIPSEENIVKATITEETIKDRKDPELEKLPEGEVRPTL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHCCCCCCHHHCCCCCCCCCC
KTEKKNKARKDIETA
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA