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The map label for this gene is msmR [H]

Identifier: 18310322

GI number: 18310322

Start: 1582126

End: 1583139

Strand: Reverse

Name: msmR [H]

Synonym: CPE1340

Alternate gene names: 18310322

Gene position: 1583139-1582126 (Counterclockwise)

Preceding gene: 18310326

Following gene: 18310320

Centisome position: 52.22

GC content: 30.08

Gene sequence:

>1014_bases
GTGGCTACTATTAAAGATATTGCAAAGGGTGCTGGAGTTTCAATAGCTACTGTATCTAGAGTTTTAAATTTAGATGAAAC
GCTTAACGTATCTGAAGAAACAAGAAAAAAAGTAATGGAAATAGCTGAAGAGTTAAATTATGTACCAGTAAAAGAAAGAA
AAAATAAAATAAAAAATTACACCATAGGAATAGTTTATTGGTACACAGAAATACAGGAATTAAACGATCCATATTTTCTT
TCAATAAGAATGGCTGTTGAGAAAAAGTGTAATGAAGAAAAAATTAAATTTAAACCAATAGATTTTCAAAAGATAATTAA
TGAAGGAACAAGAGAATATAGGGATTTAGATGGAATATTGGCTATTGGAATATTTGAAGAAGAAGAGATAAGCTTAATGG
AGAAGTTATCAAAGAACATAATTTTTGTAGATTCTTCTCCAGAAGAGTGGAAATACGATTCAGTGGTAGTAGATTTTAAG
TATGGAGTAAATATTTGTTTAGATTATTTAACATCCTTAGGCCATAAAGATATTGGATATTTAGGTGGTGAATCAATTCC
CCATAATGGCAATGAGTCCATAAGAAAGGTAAATTACAGAGAGAAAACCTTTAAAGAATATATGGAGAAAATGGGTAACT
ATAAAGAAAAGTGGGTTCTAAAGGGAAGATTTTTACCAGAGCATGGTTATGAACTTATGAAGAAGGTATTAAAAGAGAAG
GATCTTCCTACAGCATTTTTTATAGCTAGTGATCCTATGGCCATAGGAGCCTACAAAGCAATATTTGAAGAAGGATTAAG
AATACCAGAGGATATAAGTATATTAGGTTTTGATGATATATGTACTGCTAAATTTTTAACACCTTCCTTGACAACAATAA
AAGTTTTTACAGATCATATGGGAAGTATTGCCGTTGAGACACTTTTAGAGAGAATGAGAACAGGAAGAGAAATAGCTAAG
AAAATAGTTTTACCTGTAAAATTAATAGAAAGAGAAAGTTGCAAAAGACTTTAA

Upstream 100 bases:

>100_bases
TATTTGTTTAGTTAAATTTTATATATTATACAAAGAAAAGGTTAGAAAATTTTAGTAAAAAAATATATAATATAAAATAA
GAAAAGTAAGGAGTGATTAT

Downstream 100 bases:

>100_bases
AGATAAATTTAATTTTATTTACTAAAAGAGACTACATGAAATTTTTTATGTAGTCTCTTTTAGTTATGGTAAAAATAATT
TTAAAATATAAATTAAGATT

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MATIKDIAKGAGVSIATVSRVLNLDETLNVSEETRKKVMEIAEELNYVPVKERKNKIKNYTIGIVYWYTEIQELNDPYFL
SIRMAVEKKCNEEKIKFKPIDFQKIINEGTREYRDLDGILAIGIFEEEEISLMEKLSKNIIFVDSSPEEWKYDSVVVDFK
YGVNICLDYLTSLGHKDIGYLGGESIPHNGNESIRKVNYREKTFKEYMEKMGNYKEKWVLKGRFLPEHGYELMKKVLKEK
DLPTAFFIASDPMAIGAYKAIFEEGLRIPEDISILGFDDICTAKFLTPSLTTIKVFTDHMGSIAVETLLERMRTGREIAK
KIVLPVKLIERESCKRL

Sequences:

>Translated_337_residues
MATIKDIAKGAGVSIATVSRVLNLDETLNVSEETRKKVMEIAEELNYVPVKERKNKIKNYTIGIVYWYTEIQELNDPYFL
SIRMAVEKKCNEEKIKFKPIDFQKIINEGTREYRDLDGILAIGIFEEEEISLMEKLSKNIIFVDSSPEEWKYDSVVVDFK
YGVNICLDYLTSLGHKDIGYLGGESIPHNGNESIRKVNYREKTFKEYMEKMGNYKEKWVLKGRFLPEHGYELMKKVLKEK
DLPTAFFIASDPMAIGAYKAIFEEGLRIPEDISILGFDDICTAKFLTPSLTTIKVFTDHMGSIAVETLLERMRTGREIAK
KIVLPVKLIERESCKRL
>Mature_336_residues
ATIKDIAKGAGVSIATVSRVLNLDETLNVSEETRKKVMEIAEELNYVPVKERKNKIKNYTIGIVYWYTEIQELNDPYFLS
IRMAVEKKCNEEKIKFKPIDFQKIINEGTREYRDLDGILAIGIFEEEEISLMEKLSKNIIFVDSSPEEWKYDSVVVDFKY
GVNICLDYLTSLGHKDIGYLGGESIPHNGNESIRKVNYREKTFKEYMEKMGNYKEKWVLKGRFLPEHGYELMKKVLKEKD
LPTAFFIASDPMAIGAYKAIFEEGLRIPEDISILGFDDICTAKFLTPSLTTIKVFTDHMGSIAVETLLERMRTGREIAKK
IVLPVKLIERESCKRL

Specific function: Repressor For Beta Galactosidase Alpha And Beta Subunits (Ebga And Ebgc). Binds Lactose As An Inducer. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789456, Length=338, Percent_Identity=37.5739644970414, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1787948, Length=344, Percent_Identity=33.1395348837209, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1790194, Length=344, Percent_Identity=29.0697674418605, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790369, Length=345, Percent_Identity=29.5652173913043, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1786540, Length=343, Percent_Identity=26.8221574344023, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1788474, Length=324, Percent_Identity=27.7777777777778, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1789202, Length=310, Percent_Identity=27.0967741935484, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1789068, Length=346, Percent_Identity=27.4566473988439, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787580, Length=351, Percent_Identity=25.9259259259259, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790689, Length=330, Percent_Identity=24.8484848484848, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38846; Mature: 38714

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIKDIAKGAGVSIATVSRVLNLDETLNVSEETRKKVMEIAEELNYVPVKERKNKIKNY
CCCHHHHHCCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCE
TIGIVYWYTEIQELNDPYFLSIRMAVEKKCNEEKIKFKPIDFQKIINEGTREYRDLDGIL
EEEEEEEEEHHHHCCCCEEEEEEEHHHHCCCCCCCEECCCCHHHHHHHHHHHHHCCCCEE
AIGIFEEEEISLMEKLSKNIIFVDSSPEEWKYDSVVVDFKYGVNICLDYLTSLGHKDIGY
EEEECCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCC
LGGESIPHNGNESIRKVNYREKTFKEYMEKMGNYKEKWVLKGRFLPEHGYELMKKVLKEK
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHHHHHHHHHHC
DLPTAFFIASDPMAIGAYKAIFEEGLRIPEDISILGFDDICTAKFLTPSLTTIKVFTDHM
CCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHCCCCCCEEEEHHHHH
GSIAVETLLERMRTGREIAKKIVLPVKLIERESCKRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATIKDIAKGAGVSIATVSRVLNLDETLNVSEETRKKVMEIAEELNYVPVKERKNKIKNY
CCHHHHHCCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCE
TIGIVYWYTEIQELNDPYFLSIRMAVEKKCNEEKIKFKPIDFQKIINEGTREYRDLDGIL
EEEEEEEEEHHHHCCCCEEEEEEEHHHHCCCCCCCEECCCCHHHHHHHHHHHHHCCCCEE
AIGIFEEEEISLMEKLSKNIIFVDSSPEEWKYDSVVVDFKYGVNICLDYLTSLGHKDIGY
EEEECCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCC
LGGESIPHNGNESIRKVNYREKTFKEYMEKMGNYKEKWVLKGRFLPEHGYELMKKVLKEK
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHHHHHHHHHHC
DLPTAFFIASDPMAIGAYKAIFEEGLRIPEDISILGFDDICTAKFLTPSLTTIKVFTDHM
CCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHCCCCCCEEEEHHHHH
GSIAVETLLERMRTGREIAKKIVLPVKLIERESCKRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]