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The map label for this gene is gapC [H]

Identifier: 18310286

GI number: 18310286

Start: 1543708

End: 1544706

Strand: Reverse

Name: gapC [H]

Synonym: CPE1304

Alternate gene names: 18310286

Gene position: 1544706-1543708 (Counterclockwise)

Preceding gene: 18310287

Following gene: 18310285

Centisome position: 50.96

GC content: 37.34

Gene sequence:

>999_bases
ATGGTAAAAGTAGCTATTAACGGATTTGGAAGAATAGGAAGATTAGCGTTAAGATTAATGATCGACAACCCTGAGTTTGA
GGTTGTAGCAATCAACGACTTAACTGATGCTAAGACTTTAGCACACTTATTCAAATACGATTCAGCACAAGGAAGATTCA
ATGGTGAAATAGAAGTTAAAGAAGGAGCTTTCGTAGTTAACGGAAAAGAAATCAAAGTAACTGCTAAAAGCAACCCTGCT
GAATTACCATGGGGAGAATTAGGAGTAGACGTAGTATTAGAGTGTACTGGATTCTTCGCATCAAAAGAGAAAGCTTCAGC
TCACTTAACTGCTGGTGCTAAAAAAGTTGTTATCTCAGCTCCTGCTGGAAACGACCTACCAACAGTTGTTTACAACGTAA
ACCACGATATATTAGATGGAAGCGAAGATGTTATCTCAGGTGCTTCATGTACTACAAACTGCTTAGCTCCAATGGCTAAA
GCTTTAAATGATAACTTCGGATTAAACAAAGGTTTCATGACTACAATCCACGCTTACACTAACGACCAAAACACTTTAGA
TGCTCCACACAAAAAAGGAGACTTAAGAAGAGCTAGAGCTGCTGCTGCTAACATAGTTCCAAACTCAACTGGAGCTGCTA
AAGCTATCGGTTTAGTTATCCCAGAATTAGCTGGTAAATTAGACGGAAACGCTCAAAGAGTACCTGTAATAACTGGTTCA
TTAACTGAGTTAGTTTGTACTTTAGATAAAAAAGTAACAGTAGAAGAAGTAAACGCTGCTATGAAAGCTGCTTCAAACGA
ATCATTCGGATACACTGAAGATCCAATAGTATCATCAGACGTTATCGGAATAAGCTTCGGATCATTATTCGATGCTACTC
AAACTAAAATAATGGAAGTTGACGGACAACAATTAGTTAAAGTTGCTTCATGGTATGACAACGAAGCTTCATACACTAAC
CAATTAATCAGAACTTTAAAATGCTTAGTTTCTAAGTAA

Upstream 100 bases:

>100_bases
AGATGAATAAAAAAATATGAAATCTCTAAAAATAACTTTGTTTAAAATATTTTTAAATATTTTATATATAAAAAACAACA
TCTTTTAGGAGGTATTTATA

Downstream 100 bases:

>100_bases
TTTTTAAAATTAAATATTTAGACTGATTATATAAAAGGGTCTGGTTTTATAGTTAAAGCTATGAGGCCAGACTACTTTAA
CATATAAATGATTTTTGTTT

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MVKVAINGFGRIGRLALRLMIDNPEFEVVAINDLTDAKTLAHLFKYDSAQGRFNGEIEVKEGAFVVNGKEIKVTAKSNPA
ELPWGELGVDVVLECTGFFASKEKASAHLTAGAKKVVISAPAGNDLPTVVYNVNHDILDGSEDVISGASCTTNCLAPMAK
ALNDNFGLNKGFMTTIHAYTNDQNTLDAPHKKGDLRRARAAAANIVPNSTGAAKAIGLVIPELAGKLDGNAQRVPVITGS
LTELVCTLDKKVTVEEVNAAMKAASNESFGYTEDPIVSSDVIGISFGSLFDATQTKIMEVDGQQLVKVASWYDNEASYTN
QLIRTLKCLVSK

Sequences:

>Translated_332_residues
MVKVAINGFGRIGRLALRLMIDNPEFEVVAINDLTDAKTLAHLFKYDSAQGRFNGEIEVKEGAFVVNGKEIKVTAKSNPA
ELPWGELGVDVVLECTGFFASKEKASAHLTAGAKKVVISAPAGNDLPTVVYNVNHDILDGSEDVISGASCTTNCLAPMAK
ALNDNFGLNKGFMTTIHAYTNDQNTLDAPHKKGDLRRARAAAANIVPNSTGAAKAIGLVIPELAGKLDGNAQRVPVITGS
LTELVCTLDKKVTVEEVNAAMKAASNESFGYTEDPIVSSDVIGISFGSLFDATQTKIMEVDGQQLVKVASWYDNEASYTN
QLIRTLKCLVSK
>Mature_332_residues
MVKVAINGFGRIGRLALRLMIDNPEFEVVAINDLTDAKTLAHLFKYDSAQGRFNGEIEVKEGAFVVNGKEIKVTAKSNPA
ELPWGELGVDVVLECTGFFASKEKASAHLTAGAKKVVISAPAGNDLPTVVYNVNHDILDGSEDVISGASCTTNCLAPMAK
ALNDNFGLNKGFMTTIHAYTNDQNTLDAPHKKGDLRRARAAAANIVPNSTGAAKAIGLVIPELAGKLDGNAQRVPVITGS
LTELVCTLDKKVTVEEVNAAMKAASNESFGYTEDPIVSSDVIGISFGSLFDATQTKIMEVDGQQLVKVASWYDNEASYTN
QLIRTLKCLVSK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=44.9404761904762, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=43.8805970149254, Blast_Score=275, Evalue=4e-74,
Organism=Escherichia coli, GI1788079, Length=326, Percent_Identity=50.6134969325153, Blast_Score=323, Evalue=1e-89,
Organism=Escherichia coli, GI1789295, Length=332, Percent_Identity=43.0722891566265, Blast_Score=263, Evalue=8e-72,
Organism=Caenorhabditis elegans, GI32566163, Length=341, Percent_Identity=45.7478005865103, Blast_Score=281, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17568413, Length=341, Percent_Identity=45.7478005865103, Blast_Score=281, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17534677, Length=341, Percent_Identity=45.7478005865103, Blast_Score=279, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17534679, Length=341, Percent_Identity=45.7478005865103, Blast_Score=278, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6321631, Length=328, Percent_Identity=46.0365853658537, Blast_Score=296, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6322409, Length=328, Percent_Identity=44.8170731707317, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6322468, Length=328, Percent_Identity=45.1219512195122, Blast_Score=288, Evalue=8e-79,
Organism=Drosophila melanogaster, GI17933600, Length=337, Percent_Identity=45.9940652818991, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI18110149, Length=337, Percent_Identity=45.9940652818991, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI85725000, Length=337, Percent_Identity=46.2908011869436, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI22023983, Length=337, Percent_Identity=46.2908011869436, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=44.5121951219512, Blast_Score=269, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35363; Mature: 35363

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVAINGFGRIGRLALRLMIDNPEFEVVAINDLTDAKTLAHLFKYDSAQGRFNGEIEVK
CEEEEECCCCHHCEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEEE
EGAFVVNGKEIKVTAKSNPAELPWGELGVDVVLECTGFFASKEKASAHLTAGAKKVVISA
CCEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCEEEEEEC
PAGNDLPTVVYNVNHDILDGSEDVISGASCTTNCLAPMAKALNDNFGLNKGFMTTIHAYT
CCCCCCCEEEEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEE
NDQNTLDAPHKKGDLRRARAAAANIVPNSTGAAKAIGLVIPELAGKLDGNAQRVPVITGS
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECC
LTELVCTLDKKVTVEEVNAAMKAASNESFGYTEDPIVSSDVIGISFGSLFDATQTKIMEV
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHEEEEC
DGQQLVKVASWYDNEASYTNQLIRTLKCLVSK
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKVAINGFGRIGRLALRLMIDNPEFEVVAINDLTDAKTLAHLFKYDSAQGRFNGEIEVK
CEEEEECCCCHHCEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEEE
EGAFVVNGKEIKVTAKSNPAELPWGELGVDVVLECTGFFASKEKASAHLTAGAKKVVISA
CCEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCEEEEEEC
PAGNDLPTVVYNVNHDILDGSEDVISGASCTTNCLAPMAKALNDNFGLNKGFMTTIHAYT
CCCCCCCEEEEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEE
NDQNTLDAPHKKGDLRRARAAAANIVPNSTGAAKAIGLVIPELAGKLDGNAQRVPVITGS
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECC
LTELVCTLDKKVTVEEVNAAMKAASNESFGYTEDPIVSSDVIGISFGSLFDATQTKIMEV
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHEEEEC
DGQQLVKVASWYDNEASYTNQLIRTLKCLVSK
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10463150; 11466286 [H]