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The map label for this gene is adeC

Identifier: 18310250

GI number: 18310250

Start: 1487900

End: 1489618

Strand: Reverse

Name: adeC

Synonym: CPE1268

Alternate gene names: 18310250

Gene position: 1489618-1487900 (Counterclockwise)

Preceding gene: 18310251

Following gene: 18310249

Centisome position: 49.14

GC content: 28.21

Gene sequence:

>1719_bases
ATGCAAGTAGAATTAATTATTAAAAATTTAAAGGTATATAATAGTTATTTTAAAAAATTCATAAAAAGTGATGTCTTAAT
AAATGAGGGAAAATTTCTTCATATAGGGAAAGGATATGAAGATAGATTATGGTCTGAAAATATAATAGATGGGGAAGACA
AATATATAATTCCTGGATTAATAGATATACACATGCATATAGAGAGTTCTATGACTATTCCAAGGGAATTTTCTAAGGCT
GCAATAAAACATGGGGTCACTACAGTAGTAGCTGATCCTCATGAAATTGCTAATGTTTTTGGAGTAAGAGGTATAGAAGA
ATTTATTAAATTTAAGGGAAATCTAGATATATTTTATGGCATACCTAGCTCAGTACCTTCAACTTCAAGTTCACTAGAGA
CAACAGGGGAGAAAATAACTCACAATGAGGTAAAAAGATTATTAGAGTATGATAATATTATTTGTCTTGGAGAAGTAATG
AACTTTAAAGACTTAATAGAAGATGATGATTCTAATATAAATAAAATAATAAATATAAGTAAAGAAAAAAATATACCTTT
AGAAGGGCATTGTCCTAAAATACAAGGAGTAGATTTATCACTTTATATTTATAGAGGGGTTAATGGGGATCATACTCAGC
AGTCAGTTGGATCCCTTCAAGAAAAAATTCAAAATGGTATGTTTATAGAGATGCAACATAAATCAATGACATTAGAGAAT
ATAAAATTTTTGATTGAAAATAATTTATATGAGCATTTTGCATTAGTAACAGATGATGTAATGGCAGATAAATTAGTTAA
GGGGCATCTTGATGAGATTTTAAAGGAAGCCGTAAAGCTTGGAATGTCTATAGAGAATGCAATATATGCATCTACATATA
CGCCAGCTAGAAGAATGAATCTTTTAGATAGAGGAACAATTGCACCTGGAAAGCTAGCAGATTTTATATTGTTAGATAGT
ATAGAAGATTTTAATATATATGAAGTTTATAAAAATGGGGAAATGGTTTTTAATAGAGATAAGGGGTTAAAAGAAGAGTT
TTTTGAAGATAAAAGCAAATTAGATTATAGATTTTATAATAGTATAGAATTAAATAATATTACTAAAGAAAGTTTAGAGG
TTAAAGTACCAAATAAGTATAAAAATAAAGTAAATTGTAGAACTATGAAAGTCTTAAAGAATACTACTTTTACAGAAGAG
GGAGAAGTAACTTTAAATGTTTATAATAATATTTTACAATGGGAAAAGAGTAGCTGTGCATTAATTGCTGTTTTTGAGAG
ATATGGTAAAAATAATAATATATCTTTTGGATTAGTAGAAGGAGAAATTATAAAAGAGGGAGCAATAGCAACTACTTGGG
CTCATGATCATCATAACCTTATGGTAATGGGAAGAAATATTAGTGATATGACTATAGCGGCTAATGAGGTTATAAATTCT
AGGGGAGGATATGTAGTCTCAAAAAATAATGAAGTAATTGCTAAATTAGAGTTACCAATAGGTGGAATAATCAGTGATGA
ACCTATTGAAATCATAGGAGAAAAGCTAGGGGAAGTTAGAAATGCCATGAGAGATTTAGGATATAATCATATGAATGAAA
TTATGTCATTTAGCACTTTATCTTTACCTGTTAGTCCTGCATTAAAGATAACAGATAAAGGGTTAATAGATGTTAAAAAA
GGTAGTATTGTTTCTTTATTCAAAAAAGGTCTATATTAA

Upstream 100 bases:

>100_bases
TGATAACGCTAAGGTAATTGACTTTAAGTTTGTTAATTCAGTAATGGATCAATGGGTTAATAACTGGAACAGAATAATGA
ACTAGTTTGCAGGTAGTGAA

Downstream 100 bases:

>100_bases
GTGATTATTGATTTTTATTTAGTTAGCTTTAACTTAATTACGCAAAGTAATATAAAAGGAAAGTAAGGGGATGTATCGTA
GTAGATATAGCCTCTTATTT

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MQVELIIKNLKVYNSYFKKFIKSDVLINEGKFLHIGKGYEDRLWSENIIDGEDKYIIPGLIDIHMHIESSMTIPREFSKA
AIKHGVTTVVADPHEIANVFGVRGIEEFIKFKGNLDIFYGIPSSVPSTSSSLETTGEKITHNEVKRLLEYDNIICLGEVM
NFKDLIEDDDSNINKIINISKEKNIPLEGHCPKIQGVDLSLYIYRGVNGDHTQQSVGSLQEKIQNGMFIEMQHKSMTLEN
IKFLIENNLYEHFALVTDDVMADKLVKGHLDEILKEAVKLGMSIENAIYASTYTPARRMNLLDRGTIAPGKLADFILLDS
IEDFNIYEVYKNGEMVFNRDKGLKEEFFEDKSKLDYRFYNSIELNNITKESLEVKVPNKYKNKVNCRTMKVLKNTTFTEE
GEVTLNVYNNILQWEKSSCALIAVFERYGKNNNISFGLVEGEIIKEGAIATTWAHDHHNLMVMGRNISDMTIAANEVINS
RGGYVVSKNNEVIAKLELPIGGIISDEPIEIIGEKLGEVRNAMRDLGYNHMNEIMSFSTLSLPVSPALKITDKGLIDVKK
GSIVSLFKKGLY

Sequences:

>Translated_572_residues
MQVELIIKNLKVYNSYFKKFIKSDVLINEGKFLHIGKGYEDRLWSENIIDGEDKYIIPGLIDIHMHIESSMTIPREFSKA
AIKHGVTTVVADPHEIANVFGVRGIEEFIKFKGNLDIFYGIPSSVPSTSSSLETTGEKITHNEVKRLLEYDNIICLGEVM
NFKDLIEDDDSNINKIINISKEKNIPLEGHCPKIQGVDLSLYIYRGVNGDHTQQSVGSLQEKIQNGMFIEMQHKSMTLEN
IKFLIENNLYEHFALVTDDVMADKLVKGHLDEILKEAVKLGMSIENAIYASTYTPARRMNLLDRGTIAPGKLADFILLDS
IEDFNIYEVYKNGEMVFNRDKGLKEEFFEDKSKLDYRFYNSIELNNITKESLEVKVPNKYKNKVNCRTMKVLKNTTFTEE
GEVTLNVYNNILQWEKSSCALIAVFERYGKNNNISFGLVEGEIIKEGAIATTWAHDHHNLMVMGRNISDMTIAANEVINS
RGGYVVSKNNEVIAKLELPIGGIISDEPIEIIGEKLGEVRNAMRDLGYNHMNEIMSFSTLSLPVSPALKITDKGLIDVKK
GSIVSLFKKGLY
>Mature_572_residues
MQVELIIKNLKVYNSYFKKFIKSDVLINEGKFLHIGKGYEDRLWSENIIDGEDKYIIPGLIDIHMHIESSMTIPREFSKA
AIKHGVTTVVADPHEIANVFGVRGIEEFIKFKGNLDIFYGIPSSVPSTSSSLETTGEKITHNEVKRLLEYDNIICLGEVM
NFKDLIEDDDSNINKIINISKEKNIPLEGHCPKIQGVDLSLYIYRGVNGDHTQQSVGSLQEKIQNGMFIEMQHKSMTLEN
IKFLIENNLYEHFALVTDDVMADKLVKGHLDEILKEAVKLGMSIENAIYASTYTPARRMNLLDRGTIAPGKLADFILLDS
IEDFNIYEVYKNGEMVFNRDKGLKEEFFEDKSKLDYRFYNSIELNNITKESLEVKVPNKYKNKVNCRTMKVLKNTTFTEE
GEVTLNVYNNILQWEKSSCALIAVFERYGKNNNISFGLVEGEIIKEGAIATTWAHDHHNLMVMGRNISDMTIAANEVINS
RGGYVVSKNNEVIAKLELPIGGIISDEPIEIIGEKLGEVRNAMRDLGYNHMNEIMSFSTLSLPVSPALKITDKGLIDVKK
GSIVSLFKKGLY

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=571, Percent_Identity=28.0210157618214, Blast_Score=232, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_CLOPE (Q8XKX4)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_562184.1
- ProteinModelPortal:   Q8XKX4
- GeneID:   989577
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE1268
- NMPDR:   fig|195102.1.peg.1331
- HOGENOM:   HBG725357
- OMA:   IATTWAH
- PhylomeDB:   Q8XKX4
- ProtClustDB:   CLSK567048
- BioCyc:   CPER195102:CPE1268-MONOMER
- BRENDA:   3.5.4.2
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 64764; Mature: 64764

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVELIIKNLKVYNSYFKKFIKSDVLINEGKFLHIGKGYEDRLWSENIIDGEDKYIIPGL
CEEEEEHHHHHHHHHHHHHHHHCCEEECCCCEEEECCCHHHHCCCCCCCCCCCCEEECCE
IDIHMHIESSMTIPREFSKAAIKHGVTTVVADPHEIANVFGVRGIEEFIKFKGNLDIFYG
EEEEEEECCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHCCCCHHHHHHHCCCEEEEEE
IPSSVPSTSSSLETTGEKITHNEVKRLLEYDNIICLGEVMNFKDLIEDDDSNINKIINIS
CCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCEEEEHHHCCHHHHHCCCCCCCHHEEEEC
KEKNIPLEGHCPKIQGVDLSLYIYRGVNGDHTQQSVGSLQEKIQNGMFIEMQHKSMTLEN
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHH
IKFLIENNLYEHFALVTDDVMADKLVKGHLDEILKEAVKLGMSIENAIYASTYTPARRMN
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHH
LLDRGTIAPGKLADFILLDSIEDFNIYEVYKNGEMVFNRDKGLKEEFFEDKSKLDYRFYN
HHHCCCCCCCHHHHHHEECCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHCCCEEEEC
SIELNNITKESLEVKVPNKYKNKVNCRTMKVLKNTTFTEEGEVTLNVYNNILQWEKSSCA
EEEECCCCCCCEEEECCCHHCCCCCHHHHHHHHCCCCCCCCCEEEEEHHHHHHHCCCCCC
LIAVFERYGKNNNISFGLVEGEIIKEGAIATTWAHDHHNLMVMGRNISDMTIAANEVINS
EEEEHHHHCCCCCEEEEEEECEEECCCCEEEEEECCCCEEEEEECCCCCCEEEHHHHHCC
RGGYVVSKNNEVIAKLELPIGGIISDEPIEIIGEKLGEVRNAMRDLGYNHMNEIMSFSTL
CCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEE
SLPVSPALKITDKGLIDVKKGSIVSLFKKGLY
ECCCCCCEEEECCCEEEECCCCHHHHHHHCCC
>Mature Secondary Structure
MQVELIIKNLKVYNSYFKKFIKSDVLINEGKFLHIGKGYEDRLWSENIIDGEDKYIIPGL
CEEEEEHHHHHHHHHHHHHHHHCCEEECCCCEEEECCCHHHHCCCCCCCCCCCCEEECCE
IDIHMHIESSMTIPREFSKAAIKHGVTTVVADPHEIANVFGVRGIEEFIKFKGNLDIFYG
EEEEEEECCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHCCCCHHHHHHHCCCEEEEEE
IPSSVPSTSSSLETTGEKITHNEVKRLLEYDNIICLGEVMNFKDLIEDDDSNINKIINIS
CCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCEEEEHHHCCHHHHHCCCCCCCHHEEEEC
KEKNIPLEGHCPKIQGVDLSLYIYRGVNGDHTQQSVGSLQEKIQNGMFIEMQHKSMTLEN
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHH
IKFLIENNLYEHFALVTDDVMADKLVKGHLDEILKEAVKLGMSIENAIYASTYTPARRMN
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHH
LLDRGTIAPGKLADFILLDSIEDFNIYEVYKNGEMVFNRDKGLKEEFFEDKSKLDYRFYN
HHHCCCCCCCHHHHHHEECCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHCCCEEEEC
SIELNNITKESLEVKVPNKYKNKVNCRTMKVLKNTTFTEEGEVTLNVYNNILQWEKSSCA
EEEECCCCCCCEEEECCCHHCCCCCHHHHHHHHCCCCCCCCCEEEEEHHHHHHHCCCCCC
LIAVFERYGKNNNISFGLVEGEIIKEGAIATTWAHDHHNLMVMGRNISDMTIAANEVINS
EEEEHHHHCCCCCEEEEEEECEEECCCCEEEEEECCCCEEEEEECCCCCCEEEHHHHHCC
RGGYVVSKNNEVIAKLELPIGGIISDEPIEIIGEKLGEVRNAMRDLGYNHMNEIMSFSTL
CCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEE
SLPVSPALKITDKGLIDVKKGSIVSLFKKGLY
ECCCCCCEEEECCCEEEECCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842