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The map label for this gene is accD [H]

Identifier: 18310057

GI number: 18310057

Start: 1280827

End: 1281534

Strand: Direct

Name: accD [H]

Synonym: CPE1075

Alternate gene names: 18310057

Gene position: 1280827-1281534 (Clockwise)

Preceding gene: 18310056

Following gene: 18310058

Centisome position: 42.25

GC content: 33.05

Gene sequence:

>708_bases
GTGTGTCCTAATTGTGGTCATCATTTTAAGTTAGGAGCATATGAAAGAATTAAATATTTAACAGATGAAAATACTTTTGT
TGAGTTTGACAAAAAAATGATTGGAAGAAATCCCTTAGATTTTAATGGATATGAAGAGAAGATTAAAGGATATCAAAAGA
AAAGTCATGTTATTGAAGGGGTTGTAACAGGAGAGGCTTATATTGCTCAGAGAAAAGTGGTTCTTTGTGTAATGGATTCT
AATTTTATGATGGGAAGCATGGGAACGGCTGTTGGTGAAAAAATTACTAGAGCCATTGAATATGCAACTAAAAATAGACT
TCCTTTAATAATATTTACTTGCTCTGGTGGAGCAAGAATGCAAGAGGGAATATATTCTCTTATGCAAATGGCAAAGGTTA
GTGGGGCAATTTATAGACATGGTAGAGAGAACTTATTATATATTACAGTATTAACAAATCCTACTACTGGTGGGGTAACT
GCTAGCTTTGCTATGGAAGGCGATATCATATTAAGTGAGCCAGGATGTTTAGTTGGTTTTGCAGGGAGAAGGGTAATAGA
AGGAACTATTAATGAAAAGTTGCCTGATGATTTCCAAACTGCAGAATTTTTATTGGAAAAAGGATTTATAGATAAGATAG
TACAAAGAAAAGATTTAAAACAAGTAATAACTTCTCTTTTAAGAATGCATGAGGTGGATTATGAGTAG

Upstream 100 bases:

>100_bases
AGTGAAGATGAAAAACCAAATATACCCTCTGGGTATGTGGAGCAAATGTGAAAAGTGTGCAAAAATATTATATACTGAAG
ATTTAAGAGAAAATTTTAAT

Downstream 100 bases:

>100_bases
AGAACTAATAAGAACAGCAGATGCATGGAATAAAGTAAAAATAGCTAGAGATCCTAATCGTCCTAATGCAAAATTTTACA
TAAACGAAATATTTGATGAA

Product: acetyl-CoA carboxylase carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MCPNCGHHFKLGAYERIKYLTDENTFVEFDKKMIGRNPLDFNGYEEKIKGYQKKSHVIEGVVTGEAYIAQRKVVLCVMDS
NFMMGSMGTAVGEKITRAIEYATKNRLPLIIFTCSGGARMQEGIYSLMQMAKVSGAIYRHGRENLLYITVLTNPTTGGVT
ASFAMEGDIILSEPGCLVGFAGRRVIEGTINEKLPDDFQTAEFLLEKGFIDKIVQRKDLKQVITSLLRMHEVDYE

Sequences:

>Translated_235_residues
MCPNCGHHFKLGAYERIKYLTDENTFVEFDKKMIGRNPLDFNGYEEKIKGYQKKSHVIEGVVTGEAYIAQRKVVLCVMDS
NFMMGSMGTAVGEKITRAIEYATKNRLPLIIFTCSGGARMQEGIYSLMQMAKVSGAIYRHGRENLLYITVLTNPTTGGVT
ASFAMEGDIILSEPGCLVGFAGRRVIEGTINEKLPDDFQTAEFLLEKGFIDKIVQRKDLKQVITSLLRMHEVDYE
>Mature_235_residues
MCPNCGHHFKLGAYERIKYLTDENTFVEFDKKMIGRNPLDFNGYEEKIKGYQKKSHVIEGVVTGEAYIAQRKVVLCVMDS
NFMMGSMGTAVGEKITRAIEYATKNRLPLIIFTCSGGARMQEGIYSLMQMAKVSGAIYRHGRENLLYITVLTNPTTGGVT
ASFAMEGDIILSEPGCLVGFAGRRVIEGTINEKLPDDFQTAEFLLEKGFIDKIVQRKDLKQVITSLLRMHEVDYE

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=230, Percent_Identity=44.3478260869565, Blast_Score=204, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- InterPro:   IPR020893 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 26387; Mature: 26387

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCPNCGHHFKLGAYERIKYLTDENTFVEFDKKMIGRNPLDFNGYEEKIKGYQKKSHVIEG
CCCCCCCCCCCCHHHHHHEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHE
VVTGEAYIAQRKVVLCVMDSNFMMGSMGTAVGEKITRAIEYATKNRLPLIIFTCSGGARM
EECCHHHEECCEEEEEEECCCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHH
QEGIYSLMQMAKVSGAIYRHGRENLLYITVLTNPTTGGVTASFAMEGDIILSEPGCLVGF
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEECCCEEEECCCEEEEE
AGRRVIEGTINEKLPDDFQTAEFLLEKGFIDKIVQRKDLKQVITSLLRMHEVDYE
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MCPNCGHHFKLGAYERIKYLTDENTFVEFDKKMIGRNPLDFNGYEEKIKGYQKKSHVIEG
CCCCCCCCCCCCHHHHHHEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHE
VVTGEAYIAQRKVVLCVMDSNFMMGSMGTAVGEKITRAIEYATKNRLPLIIFTCSGGARM
EECCHHHEECCEEEEEEECCCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHH
QEGIYSLMQMAKVSGAIYRHGRENLLYITVLTNPTTGGVTASFAMEGDIILSEPGCLVGF
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEECCCEEEECCCEEEEE
AGRRVIEGTINEKLPDDFQTAEFLLEKGFIDKIVQRKDLKQVITSLLRMHEVDYE
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA