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The map label for this gene is mtnN [H]

Identifier: 18310032

GI number: 18310032

Start: 1256109

End: 1256909

Strand: Direct

Name: mtnN [H]

Synonym: CPE1050

Alternate gene names: 18310032

Gene position: 1256109-1256909 (Clockwise)

Preceding gene: 18310031

Following gene: 18310034

Centisome position: 41.44

GC content: 29.84

Gene sequence:

>801_bases
TTGAATATATTACAAAAGACAACAAGTGTATTATTAGCTATATTAATTACAAGTTTTAGCTTAATTGCATGTGAAAGCAA
GAAAAATGTAGAAGCATCTAAGGAAGAAAATACTATAGGAATCATAGGTGCTATGAATGAAGAACTAGAAGTACTTCTTA
AGGATATGAAAAATCAAAAGGAAGTAAAAAGAAATGATTTAACTTTTTATGAGGGAGACTTATGGGGGCAACATGTTGTA
GCTGTTGTATCAGGAGTAGGAAAAGTTAATGCAGCTTCATGTACTCAAATATTAGCAAGTGAATTTAATGTTAAATCTTT
AATAAATATAGGGGTTGCTGGAGGAGTATCTAAAGATATATATCCAGGAGATATAGTTATAGGTGATACATATGTACAAC
ACGATGTAGATGCATCTGTTTTTGGAGATAAAATCGGACAAATACCTAGAATGGATGTTTATGATTTTAAAGCTGATGAG
AAATTATTAAACTTAGCAAAAGAGGCTGCAAAAAATGTTCCAGAGGTTAAAACTTATGTAGGAAGAATAGTATCTGGAGA
CCAATTTATTGCAGATAGTAATAAAGTTAAAGTATTAGATGAAGAGTTTAATGCTAAGGCTGTTGAAATGGAAAGTGCAG
CTATAGCTCAAGTTGCATATCTTAATAAAATTCCATTTGTAATAATACGTTCAATATCAGATAATGCTAATAATGGGGCT
CACATGGATTATAAAGAATTTATACCTGTGGGAGTTAAAAATTCAACATCAATATTAAAATCAATGTTTGAAAATATGTA
A

Upstream 100 bases:

>100_bases
TGTAATTATAAAAATATTATGTATAATTATTTGTGGAATAACGAACTATTTAATTTAAATAAAATATATAGTTCGAATAA
ATATTTTTAGGAGGGGCAAA

Downstream 100 bases:

>100_bases
TAAAAAAATCCAACTTAAAATTAAGTTGGATTTTTTATTATTAAAATTAAAATTTTGGATTTATTTCATCTCTTTGAATT
CTTTTTATCTCTTTTAATCT

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MNILQKTTSVLLAILITSFSLIACESKKNVEASKEENTIGIIGAMNEELEVLLKDMKNQKEVKRNDLTFYEGDLWGQHVV
AVVSGVGKVNAASCTQILASEFNVKSLINIGVAGGVSKDIYPGDIVIGDTYVQHDVDASVFGDKIGQIPRMDVYDFKADE
KLLNLAKEAAKNVPEVKTYVGRIVSGDQFIADSNKVKVLDEEFNAKAVEMESAAIAQVAYLNKIPFVIIRSISDNANNGA
HMDYKEFIPVGVKNSTSILKSMFENM

Sequences:

>Translated_266_residues
MNILQKTTSVLLAILITSFSLIACESKKNVEASKEENTIGIIGAMNEELEVLLKDMKNQKEVKRNDLTFYEGDLWGQHVV
AVVSGVGKVNAASCTQILASEFNVKSLINIGVAGGVSKDIYPGDIVIGDTYVQHDVDASVFGDKIGQIPRMDVYDFKADE
KLLNLAKEAAKNVPEVKTYVGRIVSGDQFIADSNKVKVLDEEFNAKAVEMESAAIAQVAYLNKIPFVIIRSISDNANNGA
HMDYKEFIPVGVKNSTSILKSMFENM
>Mature_266_residues
MNILQKTTSVLLAILITSFSLIACESKKNVEASKEENTIGIIGAMNEELEVLLKDMKNQKEVKRNDLTFYEGDLWGQHVV
AVVSGVGKVNAASCTQILASEFNVKSLINIGVAGGVSKDIYPGDIVIGDTYVQHDVDASVFGDKIGQIPRMDVYDFKADE
KLLNLAKEAAKNVPEVKTYVGRIVSGDQFIADSNKVKVLDEEFNAKAVEMESAAIAQVAYLNKIPFVIIRSISDNANNGA
HMDYKEFIPVGVKNSTSILKSMFENM

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=231, Percent_Identity=37.6623376623377, Blast_Score=130, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 29072; Mature: 29072

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILQKTTSVLLAILITSFSLIACESKKNVEASKEENTIGIIGAMNEELEVLLKDMKNQK
CCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
EVKRNDLTFYEGDLWGQHVVAVVSGVGKVNAASCTQILASEFNVKSLINIGVAGGVSKDI
HHHHCCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
YPGDIVIGDTYVQHDVDASVFGDKIGQIPRMDVYDFKADEKLLNLAKEAAKNVPEVKTYV
CCCCEEECCHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
GRIVSGDQFIADSNKVKVLDEEFNAKAVEMESAAIAQVAYLNKIPFVIIRSISDNANNGA
HHHCCCCEEEECCCCEEEECCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
HMDYKEFIPVGVKNSTSILKSMFENM
CCCHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNILQKTTSVLLAILITSFSLIACESKKNVEASKEENTIGIIGAMNEELEVLLKDMKNQK
CCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
EVKRNDLTFYEGDLWGQHVVAVVSGVGKVNAASCTQILASEFNVKSLINIGVAGGVSKDI
HHHHCCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
YPGDIVIGDTYVQHDVDASVFGDKIGQIPRMDVYDFKADEKLLNLAKEAAKNVPEVKTYV
CCCCEEECCHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
GRIVSGDQFIADSNKVKVLDEEFNAKAVEMESAAIAQVAYLNKIPFVIIRSISDNANNGA
HHHCCCCEEEECCCCEEEECCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
HMDYKEFIPVGVKNSTSILKSMFENM
CCCHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]