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The map label for this gene is cobC [C]

Identifier: 18310020

GI number: 18310020

Start: 1238989

End: 1239633

Strand: Direct

Name: cobC [C]

Synonym: CPE1038

Alternate gene names: 18310020

Gene position: 1238989-1239633 (Clockwise)

Preceding gene: 18310019

Following gene: 18310021

Centisome position: 40.87

GC content: 30.08

Gene sequence:

>645_bases
ATGATAATTTATTTAATTAGACATGGGAAGACTTATTGCAATGAGAATAAACTTTATTGTGGAATAAGTGATGTGCCTTT
AAGTGAGGAAGGAAAAAAAGAGTTAGAGGAAAAAAGAAAGAGTGTGAGTTTGCCAATATGTAAGAGAAATTTTACAAGTG
GAGCAAAAAGAGCTAATGAAACATTTAATATTTTATATCCAAATAAGAAGTATGAAGTTATAAAGGAATTTGGTGAGTAT
AATTTTGGAGACTTTGAACTAAAGTCTTATGAAATGCTAAAGGAAGACAAGGAATATTTAGACTGGATTTTAGACAAAAG
CAAGGAAGTTTCCTGTCCTAATGGTGAATCAAGAAGGGATTTTGAAAAGAGAATGAAAAAAGCATTTTTAAAATTACTTC
TAACCCTTAAGGAAGAGGGAGAAGAGGAAGCCTTAATAGTATGTCATGGAGGAAGTATAGCTTGTATTTTAGAACTCTTT
GAAAAGGAGGAATTAGACTTCTATACTTATCAACCTAAGTGTGGAGGCGGATATAAGTTAAAAGTTGAACAGGATATCAA
TAATTTAAAAGGAGATTTTTCAAGTCTAGAGTTTGAAAAAGATATAACAGATAATTTAAGACTAGAAATAATAGAAAGGT
TTTAG

Upstream 100 bases:

>100_bases
GAAGAGACTGGAAAAGTTCTTCAGTTTTTATCAAAGGAAAGTGAAGAAGTTTATAGAATATTTTTTGGAATAGGAACAAG
ATTAAAGGGTGAATAATAAG

Downstream 100 bases:

>100_bases
AAATGATAAAAATTATAATAGGATATGTTTTAGACCTAATAATAGGAGATCCTAATAATCCATATCACCCTATTAGATAT
ATAGGAAAACTAGCATCTAA

Product: alpha-ribazole-5'-phosphate phosphatase

Products: alpha-ribazole; phosphate

Alternate protein names: Alpha-Ribazole-5-Phosphate Phosphatase; Fructose-2 6-Bisphosphatase; Alpha-Ribazole Phosphatase; Phosphoglycerate Mutase Family Protein

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MIIYLIRHGKTYCNENKLYCGISDVPLSEEGKKELEEKRKSVSLPICKRNFTSGAKRANETFNILYPNKKYEVIKEFGEY
NFGDFELKSYEMLKEDKEYLDWILDKSKEVSCPNGESRRDFEKRMKKAFLKLLLTLKEEGEEEALIVCHGGSIACILELF
EKEELDFYTYQPKCGGGYKLKVEQDINNLKGDFSSLEFEKDITDNLRLEIIERF

Sequences:

>Translated_214_residues
MIIYLIRHGKTYCNENKLYCGISDVPLSEEGKKELEEKRKSVSLPICKRNFTSGAKRANETFNILYPNKKYEVIKEFGEY
NFGDFELKSYEMLKEDKEYLDWILDKSKEVSCPNGESRRDFEKRMKKAFLKLLLTLKEEGEEEALIVCHGGSIACILELF
EKEELDFYTYQPKCGGGYKLKVEQDINNLKGDFSSLEFEKDITDNLRLEIIERF
>Mature_214_residues
MIIYLIRHGKTYCNENKLYCGISDVPLSEEGKKELEEKRKSVSLPICKRNFTSGAKRANETFNILYPNKKYEVIKEFGEY
NFGDFELKSYEMLKEDKEYLDWILDKSKEVSCPNGESRRDFEKRMKKAFLKLLLTLKEEGEEEALIVCHGGSIACILELF
EKEELDFYTYQPKCGGGYKLKVEQDINNLKGDFSSLEFEKDITDNLRLEIIERF

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.3.73

Molecular weight: Translated: 25101; Mature: 25101

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIYLIRHGKTYCNENKLYCGISDVPLSEEGKKELEEKRKSVSLPICKRNFTSGAKRANE
CEEEEEECCCCEECCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCHHHHCCC
TFNILYPNKKYEVIKEFGEYNFGDFELKSYEMLKEDKEYLDWILDKSKEVSCPNGESRRD
EEEEEECCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
FEKRMKKAFLKLLLTLKEEGEEEALIVCHGGSIACILELFEKEELDFYTYQPKCGGGYKL
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCEEE
KVEQDINNLKGDFSSLEFEKDITDNLRLEIIERF
EECCCHHHHCCCHHHCEECCCCCCCHHHHHEECC
>Mature Secondary Structure
MIIYLIRHGKTYCNENKLYCGISDVPLSEEGKKELEEKRKSVSLPICKRNFTSGAKRANE
CEEEEEECCCCEECCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCHHHHCCC
TFNILYPNKKYEVIKEFGEYNFGDFELKSYEMLKEDKEYLDWILDKSKEVSCPNGESRRD
EEEEEECCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
FEKRMKKAFLKLLLTLKEEGEEEALIVCHGGSIACILELFEKEELDFYTYQPKCGGGYKL
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCEEE
KVEQDINNLKGDFSSLEFEKDITDNLRLEIIERF
EECCCHHHHCCCHHHCEECCCCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alpha-ribazole 5'-phosphate; H2O

Specific reaction: alpha-ribazole 5'-phosphate + H2O = alpha-ribazole + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA