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The map label for this gene is apeA [H]

Identifier: 18309988

GI number: 18309988

Start: 1210516

End: 1211922

Strand: Direct

Name: apeA [H]

Synonym: CPE1006

Alternate gene names: 18309988

Gene position: 1210516-1211922 (Clockwise)

Preceding gene: 18309987

Following gene: 18309989

Centisome position: 39.93

GC content: 31.27

Gene sequence:

>1407_bases
ATGAAAGATGTAAAAGTTTTAAAAAAAGAATATGAAAATGCTTGGACTAAATATGAAGAGGCAGATTTAAAACAGGTATT
TTCATTAAGTGATAGATATAGGGAGTTCATGTCAGTTGCTAAAACTGAAAGAGAATGTGTCAAGGTTTTAGCTAATATGG
CAGAAAGTAAAGGGTTTAAAAATTTTTATGAAGTTATTAAAAATGGAGAAAAAGTGACAGCTGGGGATAAACTTTATTCT
ATAAACATGGATAAAACAATAACTTTAATAAAAGTAGGTTCAGAACCATTAGAAAATGGATTAAGAATAATAGGAGCTCA
CATAGATTCTCCAAGAATGGATGTTAAACAAAATCCATTATATGAAGATTCAGGATTAGCATTATTAGATACTCATTATT
ACGGAGGAGTAAAAAAATATCAATGGGTAACTATACCTCTTGCAATACATGGAGTTGTTGTAAAAAAAGATGGAACTAGG
GTAGATATTAAAATAGGAGAAGATGAAAATGATCCTGTTTTAGGAATTTCAGATCTTTTAATCCATTTATCAGCAGATCA
ATTAGATAAAAAAGGAGCTAAAGTAGTAGAAGGAGAAGACCTAAATATTTTAGTTGGAAGTATGCCATTAAAAGGAACTG
AGGAAAAAGAGGCTGTTAAAGCTAATATATTAGTTTTATTAAATGAAAAATATGGCATAACTGAGGAAGATTTTGTATCA
GCTGAGTTAGAAGTAGTTCCTGCTGGTAAGGCAAGAGATTATGGATTAGATAGAAGTATGATTTTAGCATATGGTCACGA
TGATAGAATATGTGCATATACTTCAGCAGAAGCTTTAATGGATTTAGAAAATGTTGATAAAACATGTGTAGCATTATTAG
TTGATAAAGAAGAGATAGGTAGTGTGGGAGCTACAGGAATGCAATCAAGATTCTTTGAAAATATAATTGCAGAACTTATG
GATAGAAAAGGGGAATATTCTGAATTAAAACTTAGAAGATGTCTTCAAAATTCAATGATGTTATCAGCTGATGTTACTGC
AGCTTTTGATCCAAACTATCCTTCTGTATGTGAAAAGAAAAACACAGCTTATTTTGGACATGGAGTAGTATTTAGCAAAT
ATACAGGAGCTAGAGGAAAAGCAGGTTGCAATGATGCTAATGCAGAATATATAGCTCATTTAAGAAATATAATGGATAAG
AATGGTGTTGTATGGCAAACTGGAGAGCTTGGAAAAGTAGACCAAGGTGGCGGTGGTACAATCGCTTATATATTAGCTCA
ATACAATATGGAAGTTATAGATTGTGGAGTAGCATTACAAAATATGCATGCGCCTTTAGAAGTAGCATCTAAAGCAGATT
TATATGAAACTAAAAAATGTTATAAGGCATTTTTTGAAGAAGCATAA

Upstream 100 bases:

>100_bases
GCTATTAATATTTAAAATAAGAAAATTTCTATAGTTTGACAAAATATTACCAAAAATATAAAATTGAATTAGAAGATAAA
ATAGATTGGAGGGATATATT

Downstream 100 bases:

>100_bases
TTAATCAGTTAAGAAAGGCTGTATCAAAATATCTAATCTAATATATATGATTTAGAGTATATTAGATGTATTTATGGTAC
AGTCCTTTTTATATTAAAAT

Product: putative aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKDVKVLKKEYENAWTKYEEADLKQVFSLSDRYREFMSVAKTERECVKVLANMAESKGFKNFYEVIKNGEKVTAGDKLYS
INMDKTITLIKVGSEPLENGLRIIGAHIDSPRMDVKQNPLYEDSGLALLDTHYYGGVKKYQWVTIPLAIHGVVVKKDGTR
VDIKIGEDENDPVLGISDLLIHLSADQLDKKGAKVVEGEDLNILVGSMPLKGTEEKEAVKANILVLLNEKYGITEEDFVS
AELEVVPAGKARDYGLDRSMILAYGHDDRICAYTSAEALMDLENVDKTCVALLVDKEEIGSVGATGMQSRFFENIIAELM
DRKGEYSELKLRRCLQNSMMLSADVTAAFDPNYPSVCEKKNTAYFGHGVVFSKYTGARGKAGCNDANAEYIAHLRNIMDK
NGVVWQTGELGKVDQGGGGTIAYILAQYNMEVIDCGVALQNMHAPLEVASKADLYETKKCYKAFFEEA

Sequences:

>Translated_468_residues
MKDVKVLKKEYENAWTKYEEADLKQVFSLSDRYREFMSVAKTERECVKVLANMAESKGFKNFYEVIKNGEKVTAGDKLYS
INMDKTITLIKVGSEPLENGLRIIGAHIDSPRMDVKQNPLYEDSGLALLDTHYYGGVKKYQWVTIPLAIHGVVVKKDGTR
VDIKIGEDENDPVLGISDLLIHLSADQLDKKGAKVVEGEDLNILVGSMPLKGTEEKEAVKANILVLLNEKYGITEEDFVS
AELEVVPAGKARDYGLDRSMILAYGHDDRICAYTSAEALMDLENVDKTCVALLVDKEEIGSVGATGMQSRFFENIIAELM
DRKGEYSELKLRRCLQNSMMLSADVTAAFDPNYPSVCEKKNTAYFGHGVVFSKYTGARGKAGCNDANAEYIAHLRNIMDK
NGVVWQTGELGKVDQGGGGTIAYILAQYNMEVIDCGVALQNMHAPLEVASKADLYETKKCYKAFFEEA
>Mature_468_residues
MKDVKVLKKEYENAWTKYEEADLKQVFSLSDRYREFMSVAKTERECVKVLANMAESKGFKNFYEVIKNGEKVTAGDKLYS
INMDKTITLIKVGSEPLENGLRIIGAHIDSPRMDVKQNPLYEDSGLALLDTHYYGGVKKYQWVTIPLAIHGVVVKKDGTR
VDIKIGEDENDPVLGISDLLIHLSADQLDKKGAKVVEGEDLNILVGSMPLKGTEEKEAVKANILVLLNEKYGITEEDFVS
AELEVVPAGKARDYGLDRSMILAYGHDDRICAYTSAEALMDLENVDKTCVALLVDKEEIGSVGATGMQSRFFENIIAELM
DRKGEYSELKLRRCLQNSMMLSADVTAAFDPNYPSVCEKKNTAYFGHGVVFSKYTGARGKAGCNDANAEYIAHLRNIMDK
NGVVWQTGELGKVDQGGGGTIAYILAQYNMEVIDCGVALQNMHAPLEVASKADLYETKKCYKAFFEEA

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=458, Percent_Identity=25.764192139738, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17552916, Length=393, Percent_Identity=24.9363867684478, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321905, Length=488, Percent_Identity=26.0245901639344, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322746, Length=466, Percent_Identity=23.3905579399142, Blast_Score=90, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 51941; Mature: 51941

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDVKVLKKEYENAWTKYEEADLKQVFSLSDRYREFMSVAKTERECVKVLANMAESKGFK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
NFYEVIKNGEKVTAGDKLYSINMDKTITLIKVGSEPLENGLRIIGAHIDSPRMDVKQNPL
HHHHHHHCCCEEECCCEEEEECCCCEEEEEEECCCHHHCCEEEEEEECCCCCCCCCCCCC
YEDSGLALLDTHYYGGVKKYQWVTIPLAIHGVVVKKDGTRVDIKIGEDENDPVLGISDLL
CCCCCCEEEEEHHCCCCCEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEHHHHH
IHLSADQLDKKGAKVVEGEDLNILVGSMPLKGTEEKEAVKANILVLLNEKYGITEEDFVS
EECCHHHHHCCCCEEECCCCCEEEEECCCCCCCCHHHHHEEEEEEEEECCCCCCHHHHCC
AELEVVPAGKARDYGLDRSMILAYGHDDRICAYTSAEALMDLENVDKTCVALLVDKEEIG
EEEEEEECCCCCCCCCCCCEEEEECCCCCEEEEECHHHHHHHHHCCCEEEEEEECHHHHC
SVGATGMQSRFFENIIAELMDRKGEYSELKLRRCLQNSMMLSADVTAAFDPNYPSVCEKK
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEECEEEEECCCCCHHHCCC
NTAYFGHGVVFSKYTGARGKAGCNDANAEYIAHLRNIMDKNGVVWQTGELGKVDQGGGGT
CCEEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCE
IAYILAQYNMEVIDCGVALQNMHAPLEVASKADLYETKKCYKAFFEEA
EEEEEECCCCEEEEHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDVKVLKKEYENAWTKYEEADLKQVFSLSDRYREFMSVAKTERECVKVLANMAESKGFK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
NFYEVIKNGEKVTAGDKLYSINMDKTITLIKVGSEPLENGLRIIGAHIDSPRMDVKQNPL
HHHHHHHCCCEEECCCEEEEECCCCEEEEEEECCCHHHCCEEEEEEECCCCCCCCCCCCC
YEDSGLALLDTHYYGGVKKYQWVTIPLAIHGVVVKKDGTRVDIKIGEDENDPVLGISDLL
CCCCCCEEEEEHHCCCCCEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEHHHHH
IHLSADQLDKKGAKVVEGEDLNILVGSMPLKGTEEKEAVKANILVLLNEKYGITEEDFVS
EECCHHHHHCCCCEEECCCCCEEEEECCCCCCCCHHHHHEEEEEEEEECCCCCCHHHHCC
AELEVVPAGKARDYGLDRSMILAYGHDDRICAYTSAEALMDLENVDKTCVALLVDKEEIG
EEEEEEECCCCCCCCCCCCEEEEECCCCCEEEEECHHHHHHHHHCCCEEEEEEECHHHHC
SVGATGMQSRFFENIIAELMDRKGEYSELKLRRCLQNSMMLSADVTAAFDPNYPSVCEKK
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEECEEEEECCCCCHHHCCC
NTAYFGHGVVFSKYTGARGKAGCNDANAEYIAHLRNIMDKNGVVWQTGELGKVDQGGGGT
CCEEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCE
IAYILAQYNMEVIDCGVALQNMHAPLEVASKADLYETKKCYKAFFEEA
EEEEEECCCCEEEEHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]