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The map label for this gene is fnrL [H]

Identifier: 18309975

GI number: 18309975

Start: 1196153

End: 1196863

Strand: Direct

Name: fnrL [H]

Synonym: CPE0993

Alternate gene names: 18309975

Gene position: 1196153-1196863 (Clockwise)

Preceding gene: 18309973

Following gene: 18309977

Centisome position: 39.46

GC content: 28.83

Gene sequence:

>711_bases
ATGAAAAAATGTGATTGCAAGGGCTATAAAAGTTGTTTATGCAACAAGGAGCTTACTATATTTAAGGATTTAACAGAGGA
AGAATTTAATAAATTAGCTACTGGAATGACATGTTTTCATTTTAATAAAGGGGAATATATATGTTATGAAGGTGAAAAGC
TTTCGAAGCTATTTTTAATAAGTAAGGGAAGTGTAAAGACATCAAAACTTACTAAGGGAGGAAAAGAGCAAATAATGCAC
ATATTCTCTGTAGGGGACTATTTTGGAGAGACAAGCCTCTTTAATAATGAGGGAGGAATTTCATTTAATGCTATTGCTTT
AAATGATGTTATAGTTTGTGCCGTAGATAAGGATAAAGTTGATAGTGTCTTAGAAGAAAATCCTAGAATAGCTATAGTTG
TTTTGAAATCCTTAACTAATCGTTTAAAGGATACTGAAGAATTTGCTCATAAATTAGTAACTAATGATGTTAGAGTTAGA
ATAGCATATATGTTAAAAGAGTTTAAGAGAAAATATGGCAAAATAGAAAATGGGGAAATATTTATTGATTTACCAATTAA
TAGAGAGGATATGGCTAATTATTGCGGTATAACTAGAGAAACAATGAGTAGAAAACTCTCTATATTTGAGCACGAAGGAT
TAATAGAAATTAGAGGGAATAAATCTCTAATAATAAAAGACATAGAAAGATTAAATAAAATAATTTCATAG

Upstream 100 bases:

>100_bases
AGTATTAAAATAAATTAATTAATAGTGAAAAAATATGAATAAATATATTATAATTAATACTAAAGATATAGGATTATAAA
TAAAAAGTTAGGAGAGAGCT

Downstream 100 bases:

>100_bases
GAATAAGTGTTTCCTATGAAATTATTTTATTTTTAGAAAAAATCTATTTAAAAGTTTATTTTTTCATAACTCCTTCATAT
TTAAATGAAGGAACATAGGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKKCDCKGYKSCLCNKELTIFKDLTEEEFNKLATGMTCFHFNKGEYICYEGEKLSKLFLISKGSVKTSKLTKGGKEQIMH
IFSVGDYFGETSLFNNEGGISFNAIALNDVIVCAVDKDKVDSVLEENPRIAIVVLKSLTNRLKDTEEFAHKLVTNDVRVR
IAYMLKEFKRKYGKIENGEIFIDLPINREDMANYCGITRETMSRKLSIFEHEGLIEIRGNKSLIIKDIERLNKIIS

Sequences:

>Translated_236_residues
MKKCDCKGYKSCLCNKELTIFKDLTEEEFNKLATGMTCFHFNKGEYICYEGEKLSKLFLISKGSVKTSKLTKGGKEQIMH
IFSVGDYFGETSLFNNEGGISFNAIALNDVIVCAVDKDKVDSVLEENPRIAIVVLKSLTNRLKDTEEFAHKLVTNDVRVR
IAYMLKEFKRKYGKIENGEIFIDLPINREDMANYCGITRETMSRKLSIFEHEGLIEIRGNKSLIIKDIERLNKIIS
>Mature_236_residues
MKKCDCKGYKSCLCNKELTIFKDLTEEEFNKLATGMTCFHFNKGEYICYEGEKLSKLFLISKGSVKTSKLTKGGKEQIMH
IFSVGDYFGETSLFNNEGGISFNAIALNDVIVCAVDKDKVDSVLEENPRIAIVVLKSLTNRLKDTEEFAHKLVTNDVRVR
IAYMLKEFKRKYGKIENGEIFIDLPINREDMANYCGITRETMSRKLSIFEHEGLIEIRGNKSLIIKDIERLNKIIS

Specific function: Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=178, Percent_Identity=24.7191011235955, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789756, Length=179, Percent_Identity=27.9329608938547, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26966; Mature: 26966

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKCDCKGYKSCLCNKELTIFKDLTEEEFNKLATGMTCFHFNKGEYICYEGEKLSKLFLI
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEECCCCEEEEEEE
SKGSVKTSKLTKGGKEQIMHIFSVGDYFGETSLFNNEGGISFNAIALNDVIVCAVDKDKV
ECCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCEEEEEEEECCEEEEEECHHHH
DSVLEENPRIAIVVLKSLTNRLKDTEEFAHKLVTNDVRVRIAYMLKEFKRKYGKIENGEI
HHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEE
FIDLPINREDMANYCGITRETMSRKLSIFEHEGLIEIRGNKSLIIKDIERLNKIIS
EEEECCCHHHHHHHCCCCHHHHHHHHHHEECCCEEEECCCCEEHHHHHHHHHHHCC
>Mature Secondary Structure
MKKCDCKGYKSCLCNKELTIFKDLTEEEFNKLATGMTCFHFNKGEYICYEGEKLSKLFLI
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEECCCCEEEEEEE
SKGSVKTSKLTKGGKEQIMHIFSVGDYFGETSLFNNEGGISFNAIALNDVIVCAVDKDKV
ECCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCEEEEEEEECCEEEEEECHHHH
DSVLEENPRIAIVVLKSLTNRLKDTEEFAHKLVTNDVRVRIAYMLKEFKRKYGKIENGEI
HHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEE
FIDLPINREDMANYCGITRETMSRKLSIFEHEGLIEIRGNKSLIIKDIERLNKIIS
EEEECCCHHHHHHHCCCCHHHHHHHHHHEECCCEEEECCCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]