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The map label for this gene is sdhB [H]

Identifier: 18309970

GI number: 18309970

Start: 1191501

End: 1192181

Strand: Direct

Name: sdhB [H]

Synonym: CPE0988

Alternate gene names: 18309970

Gene position: 1191501-1192181 (Clockwise)

Preceding gene: 18309969

Following gene: 18309971

Centisome position: 39.3

GC content: 32.6

Gene sequence:

>681_bases
ATGAATAATCTTTGTGTTTTTGATATATTAGGTCCAGTAATGGTTGGACCATCATCATCTCATACAGCGGGAGCAGCTAG
ACTAGGAAAGGTAGCTAGAGCAGTTGCTGGAGAAAAAATTGTAGATGTTAAATTTTTGCTTCATGGATCTTTTGCTAAAA
CATATAAAGGTCATGGAACTGATAAGGCTTTACTTGCAGGTATATTAGGAATGAAGCCAGATGATGAAAGGCTTAGAAGT
TCATTAGCTATTGCTAAAGAGGAAGGATTAAACTTTGAATTTATAGAAAGAGATTTAGGAGATTACCATCCAAATACAGT
TAAATTTGTTATGGAGTGTGAATCTGGAAAAGTTTGCGAGGTATTAGGTTCATCAGTAGGTGGAGGAAGCATAGAAATAG
TTGAGGTAAATGGAAATGAAGCTAATTTTAGTGGAGCATATCCAACACTTATTACATGTCATGATGATAAATTTGGTACT
GTAAATAAAGTAACAAAACTTCTTCTTGAACATGAAATTAATATTGCTTTTATGAACGTTTCAAGAACTCAGAAGGGAAT
GGACGCTACCATGACTTTAGAAATAGATAATAAGATTGATGAATCTGTTATAAAGAGAATGGAAGAAATAGATGGAATAA
AAAAAGTTATACTTATAAATTTAGAAGAAGAGGGTGAATAA

Upstream 100 bases:

>100_bases
GAAATTAGAAATAATAAAGATTCTGAAAATAATTTAAATGTTGAAGATGAAGAAGTTTTAGTAGTTTAATAATGATGGAT
AAATAGAGGAAGGGATAGTT

Downstream 100 bases:

>100_bases
CATATGAGAGTTGCAAAAACTGGAGAAGAACTTTTAGATATATGTAAAGAAGAAGGGATTAAGCTTAGTGAATATGCCTT
AAGATGTGAAATGCAAAGTA

Product: L-serine dehydratase beta subunit

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MNNLCVFDILGPVMVGPSSSHTAGAARLGKVARAVAGEKIVDVKFLLHGSFAKTYKGHGTDKALLAGILGMKPDDERLRS
SLAIAKEEGLNFEFIERDLGDYHPNTVKFVMECESGKVCEVLGSSVGGGSIEIVEVNGNEANFSGAYPTLITCHDDKFGT
VNKVTKLLLEHEINIAFMNVSRTQKGMDATMTLEIDNKIDESVIKRMEEIDGIKKVILINLEEEGE

Sequences:

>Translated_226_residues
MNNLCVFDILGPVMVGPSSSHTAGAARLGKVARAVAGEKIVDVKFLLHGSFAKTYKGHGTDKALLAGILGMKPDDERLRS
SLAIAKEEGLNFEFIERDLGDYHPNTVKFVMECESGKVCEVLGSSVGGGSIEIVEVNGNEANFSGAYPTLITCHDDKFGT
VNKVTKLLLEHEINIAFMNVSRTQKGMDATMTLEIDNKIDESVIKRMEEIDGIKKVILINLEEEGE
>Mature_226_residues
MNNLCVFDILGPVMVGPSSSHTAGAARLGKVARAVAGEKIVDVKFLLHGSFAKTYKGHGTDKALLAGILGMKPDDERLRS
SLAIAKEEGLNFEFIERDLGDYHPNTVKFVMECESGKVCEVLGSSVGGGSIEIVEVNGNEANFSGAYPTLITCHDDKFGT
VNKVTKLLLEHEINIAFMNVSRTQKGMDATMTLEIDNKIDESVIKRMEEIDGIKKVILINLEEEGE

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR004643
- InterPro:   IPR005131 [H]

Pfam domain/function: PF01842 ACT; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 24530; Mature: 24530

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLCVFDILGPVMVGPSSSHTAGAARLGKVARAVAGEKIVDVKFLLHGSFAKTYKGHGT
CCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHCCCCC
DKALLAGILGMKPDDERLRSSLAIAKEEGLNFEFIERDLGDYHPNTVKFVMECESGKVCE
CHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHH
VLGSSVGGGSIEIVEVNGNEANFSGAYPTLITCHDDKFGTVNKVTKLLLEHEINIAFMNV
HHCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEC
SRTQKGMDATMTLEIDNKIDESVIKRMEEIDGIKKVILINLEEEGE
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEEEEECCCCC
>Mature Secondary Structure
MNNLCVFDILGPVMVGPSSSHTAGAARLGKVARAVAGEKIVDVKFLLHGSFAKTYKGHGT
CCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHCCCCC
DKALLAGILGMKPDDERLRSSLAIAKEEGLNFEFIERDLGDYHPNTVKFVMECESGKVCE
CHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHH
VLGSSVGGGSIEIVEVNGNEANFSGAYPTLITCHDDKFGTVNKVTKLLLEHEINIAFMNV
HHCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEC
SRTQKGMDATMTLEIDNKIDESVIKRMEEIDGIKKVILINLEEEGE
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]