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The map label for this gene is yjcC [H]

Identifier: 18309896

GI number: 18309896

Start: 1113813

End: 1115453

Strand: Direct

Name: yjcC [H]

Synonym: CPE0914

Alternate gene names: 18309896

Gene position: 1113813-1115453 (Clockwise)

Preceding gene: 18309895

Following gene: 18309897

Centisome position: 36.74

GC content: 23.95

Gene sequence:

>1641_bases
ATGAAAAAAAGGGTGTTTTGGGTAAGTATAGTATTTTTAATAATTATAACGGTTTTAGGTATTACAATTAAATTTGATGG
TAAGAAAGTTAATTGTAACAGAAAAACAGTTAAAGTAGGATTTTATGAATATTATCCTTATTATTATCTTAATAAAAATT
CTATGCCAGATGGCTATTATAATGAAATACTAGAATTAATATGCAATAAGTTAGATTTAAATTATAAGTATGTAGATTGT
AATGTAACAGATGCTTTAGAAAAGCTTAAATCTGGACAGATAGATTTAGTCTTTGGAATAAGTAAGACTCCTGATAGAGA
AAAGGAATATGAATTTACTGACCACTATCTAAATAATGATAACTTTGCCATATATACTAATAAGAATATAAAAAATGGTG
ATTTAAAAGCTTTAAATGGATTAAAAATGGGATTTTTAAAAGGAGAAGAAAATAATGAGTGGATTTTAAGGCTTTTAAAG
GATAAAGGCATAAATGTGAAACCTATATATGTTTCTAATTATCCTGAAGATGAGGAATATTTGTATAATAACAAAGTGGA
CTTTGTAGTAGAAAATACAAGAAGCAATATAAATTATGAAAATAAAAATATTAAAAAGATTTTTGAATTTTCTTCTGGAC
CTGTTTATATAGTTAGTAGAAAAGGTAATGAAAAATTAATTGAAGGAATAGATTCTGTACTTGGAGAGCTTGAGGAAGAT
GAGGAACAAAAAGATGCTAATTTATATTCTAAGTATTTTGATGAGCATTTAGATAAATTAAAAAATGAGAAATTACTAGT
TGTAATATTTTTAATTATAATATCATTATTTATTTATAAAAAAAGAAAAAATAAAATATTCGCTATAAGAACTAAAAGAA
AAATTAGAGACTATATGAAAAATGATAAATATATATTATATTATCAACCTATAGTAGATCCAAAGAAAAATAGAGTAAAA
GGATTTGAATCTCTTTTGAGATTAAATAAGGATGGAAAAATTTTAACTCCCTATAGCTTTATAAAGGAAATTGAAGACAA
TAATATGTCTTTAGAGGTTTCTTTATGGCTTTTAAAGAAGGTTATTTTAGATTACAGAATAATAAAAGATTATGATATGG
TTAAAGGAAGAGATTTTTATATATCCTTAAATGTTTCATTTAAAGAAATAGAAAATCCTAAGTTTTTAAGATCCTTAATG
AAAATTGCAAAAGATTATAAGATTGATGATTGTAATATTTGTTTAGAGATAGTAGAAAAGTTTGGTATGGAGGATATAGG
AAGAATACAAAGTGCAATAAGAATAATAAAGGAATATGGATTTTTAATAGCTATAGACGATTTTGGAGTGGAATATTCTA
ATTTAGATTTATTAAATAAAATTGATTCTGATATAGTGAAGCTAGACAAGTACTTTGCTGATAATTTAGACAAGTCTATT
ATAAATGAAAAAACAGTGGAATTTATATCAGAAATATGTATCATAGCTAATAGAACTATAGTATTTGAAGGGATAGAGGA
ACAGTATCAGGTTGACATTGTTAAGGCATTTCCATATGAAAAAATATATATTCAGGGATATTTCTATTCAAAGCCAGTAG
ATATTGAGACTTTAAAGGATTTTAAATTTAAGGATAGTTAA

Upstream 100 bases:

>100_bases
TGCTTAAATCAAGTTTATTAGAAAATTATGTTAATATTTAAATAGAGTAAAAATTTATTTAGAGATAAGGTTATATGAGA
GGTTAGGGAAGTGTTACTTT

Downstream 100 bases:

>100_bases
TTTTTAAAGGATAGAAATAGTAAGAATTAATGAGAAGGATTTATAATATAATAAGGTGGTTATAATTAGGAGGTACAAAA
AATGAAAGTATTATTAGTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MKKRVFWVSIVFLIIITVLGITIKFDGKKVNCNRKTVKVGFYEYYPYYYLNKNSMPDGYYNEILELICNKLDLNYKYVDC
NVTDALEKLKSGQIDLVFGISKTPDREKEYEFTDHYLNNDNFAIYTNKNIKNGDLKALNGLKMGFLKGEENNEWILRLLK
DKGINVKPIYVSNYPEDEEYLYNNKVDFVVENTRSNINYENKNIKKIFEFSSGPVYIVSRKGNEKLIEGIDSVLGELEED
EEQKDANLYSKYFDEHLDKLKNEKLLVVIFLIIISLFIYKKRKNKIFAIRTKRKIRDYMKNDKYILYYQPIVDPKKNRVK
GFESLLRLNKDGKILTPYSFIKEIEDNNMSLEVSLWLLKKVILDYRIIKDYDMVKGRDFYISLNVSFKEIENPKFLRSLM
KIAKDYKIDDCNICLEIVEKFGMEDIGRIQSAIRIIKEYGFLIAIDDFGVEYSNLDLLNKIDSDIVKLDKYFADNLDKSI
INEKTVEFISEICIIANRTIVFEGIEEQYQVDIVKAFPYEKIYIQGYFYSKPVDIETLKDFKFKDS

Sequences:

>Translated_546_residues
MKKRVFWVSIVFLIIITVLGITIKFDGKKVNCNRKTVKVGFYEYYPYYYLNKNSMPDGYYNEILELICNKLDLNYKYVDC
NVTDALEKLKSGQIDLVFGISKTPDREKEYEFTDHYLNNDNFAIYTNKNIKNGDLKALNGLKMGFLKGEENNEWILRLLK
DKGINVKPIYVSNYPEDEEYLYNNKVDFVVENTRSNINYENKNIKKIFEFSSGPVYIVSRKGNEKLIEGIDSVLGELEED
EEQKDANLYSKYFDEHLDKLKNEKLLVVIFLIIISLFIYKKRKNKIFAIRTKRKIRDYMKNDKYILYYQPIVDPKKNRVK
GFESLLRLNKDGKILTPYSFIKEIEDNNMSLEVSLWLLKKVILDYRIIKDYDMVKGRDFYISLNVSFKEIENPKFLRSLM
KIAKDYKIDDCNICLEIVEKFGMEDIGRIQSAIRIIKEYGFLIAIDDFGVEYSNLDLLNKIDSDIVKLDKYFADNLDKSI
INEKTVEFISEICIIANRTIVFEGIEEQYQVDIVKAFPYEKIYIQGYFYSKPVDIETLKDFKFKDS
>Mature_546_residues
MKKRVFWVSIVFLIIITVLGITIKFDGKKVNCNRKTVKVGFYEYYPYYYLNKNSMPDGYYNEILELICNKLDLNYKYVDC
NVTDALEKLKSGQIDLVFGISKTPDREKEYEFTDHYLNNDNFAIYTNKNIKNGDLKALNGLKMGFLKGEENNEWILRLLK
DKGINVKPIYVSNYPEDEEYLYNNKVDFVVENTRSNINYENKNIKKIFEFSSGPVYIVSRKGNEKLIEGIDSVLGELEED
EEQKDANLYSKYFDEHLDKLKNEKLLVVIFLIIISLFIYKKRKNKIFAIRTKRKIRDYMKNDKYILYYQPIVDPKKNRVK
GFESLLRLNKDGKILTPYSFIKEIEDNNMSLEVSLWLLKKVILDYRIIKDYDMVKGRDFYISLNVSFKEIENPKFLRSLM
KIAKDYKIDDCNICLEIVEKFGMEDIGRIQSAIRIIKEYGFLIAIDDFGVEYSNLDLLNKIDSDIVKLDKYFADNLDKSI
INEKTVEFISEICIIANRTIVFEGIEEQYQVDIVKAFPYEKIYIQGYFYSKPVDIETLKDFKFKDS

Specific function: Overexpression reduces biofilm formation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=254, Percent_Identity=27.5590551181102, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI87081845, Length=282, Percent_Identity=25.177304964539, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081743, Length=258, Percent_Identity=27.906976744186, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787541, Length=241, Percent_Identity=23.2365145228216, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI226510982, Length=257, Percent_Identity=25.6809338521401, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082096, Length=312, Percent_Identity=25, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787055, Length=251, Percent_Identity=28.2868525896414, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081921, Length=255, Percent_Identity=25.0980392156863, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788502, Length=253, Percent_Identity=25.296442687747, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788849, Length=268, Percent_Identity=21.2686567164179, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786507, Length=251, Percent_Identity=23.9043824701195, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081980, Length=256, Percent_Identity=24.609375, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 64553; Mature: 64553

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRVFWVSIVFLIIITVLGITIKFDGKKVNCNRKTVKVGFYEYYPYYYLNKNSMPDGYY
CCCEEHHHHHHHHHHHHHHCEEEEECCEEECCCCEEEEEEEEEECCEEEEECCCCCCHHH
NEILELICNKLDLNYKYVDCNVTDALEKLKSGQIDLVFGISKTPDREKEYEFTDHYLNND
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHEECCC
NFAIYTNKNIKNGDLKALNGLKMGFLKGEENNEWILRLLKDKGINVKPIYVSNYPEDEEY
CEEEEECCCCCCCCHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHH
LYNNKVDFVVENTRSNINYENKNIKKIFEFSSGPVYIVSRKGNEKLIEGIDSVLGELEED
HCCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCH
EEQKDANLYSKYFDEHLDKLKNEKLLVVIFLIIISLFIYKKRKNKIFAIRTKRKIRDYMK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHC
NDKYILYYQPIVDPKKNRVKGFESLLRLNKDGKILTPYSFIKEIEDNNMSLEVSLWLLKK
CCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEECHHHHHHHHCCCCCEEEEHHHHHHH
VILDYRIIKDYDMVKGRDFYISLNVSFKEIENPKFLRSLMKIAKDYKIDDCNICLEIVEK
HHHHHHHCCCCCCCCCCEEEEEEEEEHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FGMEDIGRIQSAIRIIKEYGFLIAIDDFGVEYSNLDLLNKIDSDIVKLDKYFADNLDKSI
HCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHH
INEKTVEFISEICIIANRTIVFEGIEEQYQVDIVKAFPYEKIYIQGYFYSKPVDIETLKD
HHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEECCCEEEEEEEEEECCCCCHHHHCC
FKFKDS
CCCCCC
>Mature Secondary Structure
MKKRVFWVSIVFLIIITVLGITIKFDGKKVNCNRKTVKVGFYEYYPYYYLNKNSMPDGYY
CCCEEHHHHHHHHHHHHHHCEEEEECCEEECCCCEEEEEEEEEECCEEEEECCCCCCHHH
NEILELICNKLDLNYKYVDCNVTDALEKLKSGQIDLVFGISKTPDREKEYEFTDHYLNND
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHEECCC
NFAIYTNKNIKNGDLKALNGLKMGFLKGEENNEWILRLLKDKGINVKPIYVSNYPEDEEY
CEEEEECCCCCCCCHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHH
LYNNKVDFVVENTRSNINYENKNIKKIFEFSSGPVYIVSRKGNEKLIEGIDSVLGELEED
HCCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCH
EEQKDANLYSKYFDEHLDKLKNEKLLVVIFLIIISLFIYKKRKNKIFAIRTKRKIRDYMK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHC
NDKYILYYQPIVDPKKNRVKGFESLLRLNKDGKILTPYSFIKEIEDNNMSLEVSLWLLKK
CCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEECHHHHHHHHCCCCCEEEEHHHHHHH
VILDYRIIKDYDMVKGRDFYISLNVSFKEIENPKFLRSLMKIAKDYKIDDCNICLEIVEK
HHHHHHHCCCCCCCCCCEEEEEEEEEHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FGMEDIGRIQSAIRIIKEYGFLIAIDDFGVEYSNLDLLNKIDSDIVKLDKYFADNLDKSI
HCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHH
INEKTVEFISEICIIANRTIVFEGIEEQYQVDIVKAFPYEKIYIQGYFYSKPVDIETLKD
HHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEECCCEEEEEEEEEECCCCCHHHHCC
FKFKDS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]