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The map label for this gene is yxdK [H]

Identifier: 18309823

GI number: 18309823

Start: 1029353

End: 1030363

Strand: Direct

Name: yxdK [H]

Synonym: CPE0841

Alternate gene names: 18309823

Gene position: 1029353-1030363 (Clockwise)

Preceding gene: 18309822

Following gene: 18309824

Centisome position: 33.96

GC content: 26.31

Gene sequence:

>1011_bases
ATGAAACTAAGGGATTACTTTGAGGATAAAACATTCTTTTTAATTGTAAACTTTATAATTTTTGCCACTATAGGAGTTTT
ATTGTTCATAGGCAATGTTGGTTCAGGAATAATATTTTTAATAGGATGCTTTTGGTTTATTCCTCTTTTTACATATATAA
TTTTAGATTTTTATAAGAGTAAAAAATTCTATGATAACATAAGCATTACTTTAGATAAATTAGACAGAAAGTACCTATTA
CCTGAGGTAATAGAAGAGCCAAATTTCTATCATGGTAAATTTTTATATGAGGTTTTAAAAGAAACTGATAAAGATATGCA
TGAGCATGTTAAAAAATATATACTGGAGCAAAAAGAATATAGAGAATATATAGAAACATGGGTTCATGAGATAAAAACTC
CAATAGCTTCTACTAGACTTATTTTAGAAAATAACGAGAGTGAGTCTAGTGAAAATATCAAAAAGGAAATAAAGAAAATT
GAAGAATATATAGATCAAGCTTTATATTATGCTAGAAGTACAGATGTTAGCAAAGATTATATTGTAAAAGAATTTTCCTT
AGGGAAAAGTGTAAGAAATGTAATTAAGAAAAATTCTAGGGATTTCATAAATAAGAGAATAGCTATAGACTTAGAGGATT
TAGATTATAAGGTTTATAGTGATGAAAAATGGGTTGAATTTATAATAAATCAAGTTATAAATAACGCAATAAAATATAGT
GCTAAAAATAGTAGAGTCAAAATATTTGCAAATAAATCTAAAAATAGCATAACTCTTAAAATAAAAGATAGTGGTGTTGG
AATACATAATAAAGATTTAGGTAGAGTTTTTGAAAAAGGCTTTACTGGAGAAAATGGAAGAAGATTTACTAAATCTACAG
GTATGGGGTTATACCTATGCAAAAATCTTTGTGATAAGTTAGGCTTAGGCTTAAAAATAACTTCAGAAGAAAATGAGGGA
ACAGAAGTTAACATAATTTTCCCAATAGGAGATGCCATAATAGCCAATTAA

Upstream 100 bases:

>100_bases
ACACACTTTCAGTAAATGTAACTAGACTTAGAAAAAAATTAGAAGAGGTTGGAGTAAAAGGCGCTATAGAAACTAGAAGG
GGATTAGGGTATATTATGCC

Downstream 100 bases:

>100_bases
TGAAATAAATTTGAATTTAAAAATACAATTAGTTTAAATAATGAAAACTAATTGTATTTTTAGATTAATTATATGATATT
TAGTGTTTTTAAACCTAAAA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKLRDYFEDKTFFLIVNFIIFATIGVLLFIGNVGSGIIFLIGCFWFIPLFTYIILDFYKSKKFYDNISITLDKLDRKYLL
PEVIEEPNFYHGKFLYEVLKETDKDMHEHVKKYILEQKEYREYIETWVHEIKTPIASTRLILENNESESSENIKKEIKKI
EEYIDQALYYARSTDVSKDYIVKEFSLGKSVRNVIKKNSRDFINKRIAIDLEDLDYKVYSDEKWVEFIINQVINNAIKYS
AKNSRVKIFANKSKNSITLKIKDSGVGIHNKDLGRVFEKGFTGENGRRFTKSTGMGLYLCKNLCDKLGLGLKITSEENEG
TEVNIIFPIGDAIIAN

Sequences:

>Translated_336_residues
MKLRDYFEDKTFFLIVNFIIFATIGVLLFIGNVGSGIIFLIGCFWFIPLFTYIILDFYKSKKFYDNISITLDKLDRKYLL
PEVIEEPNFYHGKFLYEVLKETDKDMHEHVKKYILEQKEYREYIETWVHEIKTPIASTRLILENNESESSENIKKEIKKI
EEYIDQALYYARSTDVSKDYIVKEFSLGKSVRNVIKKNSRDFINKRIAIDLEDLDYKVYSDEKWVEFIINQVINNAIKYS
AKNSRVKIFANKSKNSITLKIKDSGVGIHNKDLGRVFEKGFTGENGRRFTKSTGMGLYLCKNLCDKLGLGLKITSEENEG
TEVNIIFPIGDAIIAN
>Mature_336_residues
MKLRDYFEDKTFFLIVNFIIFATIGVLLFIGNVGSGIIFLIGCFWFIPLFTYIILDFYKSKKFYDNISITLDKLDRKYLL
PEVIEEPNFYHGKFLYEVLKETDKDMHEHVKKYILEQKEYREYIETWVHEIKTPIASTRLILENNESESSENIKKEIKKI
EEYIDQALYYARSTDVSKDYIVKEFSLGKSVRNVIKKNSRDFINKRIAIDLEDLDYKVYSDEKWVEFIINQVINNAIKYS
AKNSRVKIFANKSKNSITLKIKDSGVGIHNKDLGRVFEKGFTGENGRRFTKSTGMGLYLCKNLCDKLGLGLKITSEENEG
TEVNIIFPIGDAIIAN

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790861, Length=201, Percent_Identity=22.8855721393035, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39199; Mature: 39199

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRDYFEDKTFFLIVNFIIFATIGVLLFIGNVGSGIIFLIGCFWFIPLFTYIILDFYKS
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KKFYDNISITLDKLDRKYLLPEVIEEPNFYHGKFLYEVLKETDKDMHEHVKKYILEQKEY
HHHHCCCEEEHHHHCHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REYIETWVHEIKTPIASTRLILENNESESSENIKKEIKKIEEYIDQALYYARSTDVSKDY
HHHHHHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IVKEFSLGKSVRNVIKKNSRDFINKRIAIDLEDLDYKVYSDEKWVEFIINQVINNAIKYS
HHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHCC
AKNSRVKIFANKSKNSITLKIKDSGVGIHNKDLGRVFEKGFTGENGRRFTKSTGMGLYLC
CCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEHHCCCCHHHHH
KNLCDKLGLGLKITSEENEGTEVNIIFPIGDAIIAN
HHHHHHHCCCEEEECCCCCCCEEEEEEECCCHHHCC
>Mature Secondary Structure
MKLRDYFEDKTFFLIVNFIIFATIGVLLFIGNVGSGIIFLIGCFWFIPLFTYIILDFYKS
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KKFYDNISITLDKLDRKYLLPEVIEEPNFYHGKFLYEVLKETDKDMHEHVKKYILEQKEY
HHHHCCCEEEHHHHCHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REYIETWVHEIKTPIASTRLILENNESESSENIKKEIKKIEEYIDQALYYARSTDVSKDY
HHHHHHHHHHHHCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IVKEFSLGKSVRNVIKKNSRDFINKRIAIDLEDLDYKVYSDEKWVEFIINQVINNAIKYS
HHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHCC
AKNSRVKIFANKSKNSITLKIKDSGVGIHNKDLGRVFEKGFTGENGRRFTKSTGMGLYLC
CCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEHHCCCCHHHHH
KNLCDKLGLGLKITSEENEGTEVNIIFPIGDAIIAN
HHHHHHHCCCEEEECCCCCCCEEEEEEECCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]