Click here to switch to the map view.

The map label for this gene is norM [H]

Identifier: 18309821

GI number: 18309821

Start: 1027186

End: 1028502

Strand: Direct

Name: norM [H]

Synonym: CPE0839

Alternate gene names: 18309821

Gene position: 1027186-1028502 (Clockwise)

Preceding gene: 18309820

Following gene: 18309822

Centisome position: 33.88

GC content: 30.07

Gene sequence:

>1317_bases
ATGAAGAAAATAGATTTAACCAAGGGTAAGGTACTAAGTGTGCTTACCACCCTAGCTCTTCCTATTATGGGAAGTTCATT
CCTTCAGTTTGCTTATGGGCTTATAGATATGTTTTGGGTTGGAGGTCTTGGAAGTAGTGCAGTGGCTAGCATTGGTTCTT
CAAGCTTCTTTTTAGGACTAGGATATTCTATAAATGCTTTAGTAGTGACAGGAACTGGAATTAAGGTTTCTCATGAGGTA
GGGAGAAAAAATGAAATAGAGACAGAGGATTATATAAGAAATGGTCTTATAATGAATTTTCTTATAGGACTAATATATGC
ATTAATCTTAGTTGTTTTTGGAAAAGGATTCATAGGATTTTTAAATTTAAATGATCCTTTAGTTGAAAGAGATTCTTATA
TATACTTAGCTGTAAGTGCCCCAGTATTATTTTTTAGCTTTTTTAATTATCTTTTTACTAGAATATTAGCTAGCTTTGGT
AATAATAAATTAGCTTTAAAAATAAGTGCTACAGGTATAATTTTAAATATGATATTAGATCCAATATTAATATATGTTTT
TAAACTTGGTGTTTTTGGAGCAGCGGTGGCAACTTTACTTGCCAATATACTTATGTTTTTTATGTATATATATTATGGAA
AAGGAATATTTAAAATAGATTTAAAAAAGAAAGTAAACTATGAAAAAGTAAGAGAAATAGCTAGATTAGGATTTCCTATG
GCATCTCAAAGGGTACTTTTTACCTTAGTGAATATTATATTAGCTAGAATTATAGCTAGTTTTGGAGCTGATGCTATAGC
AGCTCAGAAAATAGGCCTTCAAATAGAATCTGTAAGTTTTATGGTAGTTGGAGGATTAAACGGGGCTATAGCAGGGTTTA
CAGGACAAAATTATGGAGCCAAAAAATTAAATAGAGTAAATGAAGGATATAAGAAAGCCTTGCTTTTAGGAGCTATCTAT
TCAATACTTGTTTCAGCCTTATTTATTTGTATTCCAGGATTATTAGTAGGATTATTTGTTAAGGATGAGGCTACAATAAT
AATTGGAAGCAGTTATTTAAGAGTACTTGGAATAGTTCAGATATTTAGTAGTTTTGAGATGATATCAAATGGAGTATTCT
CAGGATTAGGACTTCCTAAAATACCATCAGCCATAAGTATAATCTTTACTATGTTAAGAATTCCTATGGCCTTAGTTTTA
GTTAAGTTTTTAGGGATAAATGGAGTTTGGTGGAGCATTGCAATATCAAACATATTAAAAGGAAGCACATCTTGTATAAT
TTATAGATTAAAAATTTATAGAAACTATATTGTGTAA

Upstream 100 bases:

>100_bases
GATGAAGAGTTTATATACACAAGAGATAAAATAAAAGAAAAGGTAGAGGATTTAGTAATTCGTATAAAAAATGGGCAAAT
TTAAATAGGAGAAAGTGTAA

Downstream 100 bases:

>100_bases
TTAATAGTATTTTTCATTATGACTGTATTAGGGAACTTAAATTAAAAAGTGCTTTAATACAGTTTTTTTTATATAATAAA
TTAAAGACAATAAAATCGTA

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MKKIDLTKGKVLSVLTTLALPIMGSSFLQFAYGLIDMFWVGGLGSSAVASIGSSSFFLGLGYSINALVVTGTGIKVSHEV
GRKNEIETEDYIRNGLIMNFLIGLIYALILVVFGKGFIGFLNLNDPLVERDSYIYLAVSAPVLFFSFFNYLFTRILASFG
NNKLALKISATGIILNMILDPILIYVFKLGVFGAAVATLLANILMFFMYIYYGKGIFKIDLKKKVNYEKVREIARLGFPM
ASQRVLFTLVNIILARIIASFGADAIAAQKIGLQIESVSFMVVGGLNGAIAGFTGQNYGAKKLNRVNEGYKKALLLGAIY
SILVSALFICIPGLLVGLFVKDEATIIIGSSYLRVLGIVQIFSSFEMISNGVFSGLGLPKIPSAISIIFTMLRIPMALVL
VKFLGINGVWWSIAISNILKGSTSCIIYRLKIYRNYIV

Sequences:

>Translated_438_residues
MKKIDLTKGKVLSVLTTLALPIMGSSFLQFAYGLIDMFWVGGLGSSAVASIGSSSFFLGLGYSINALVVTGTGIKVSHEV
GRKNEIETEDYIRNGLIMNFLIGLIYALILVVFGKGFIGFLNLNDPLVERDSYIYLAVSAPVLFFSFFNYLFTRILASFG
NNKLALKISATGIILNMILDPILIYVFKLGVFGAAVATLLANILMFFMYIYYGKGIFKIDLKKKVNYEKVREIARLGFPM
ASQRVLFTLVNIILARIIASFGADAIAAQKIGLQIESVSFMVVGGLNGAIAGFTGQNYGAKKLNRVNEGYKKALLLGAIY
SILVSALFICIPGLLVGLFVKDEATIIIGSSYLRVLGIVQIFSSFEMISNGVFSGLGLPKIPSAISIIFTMLRIPMALVL
VKFLGINGVWWSIAISNILKGSTSCIIYRLKIYRNYIV
>Mature_438_residues
MKKIDLTKGKVLSVLTTLALPIMGSSFLQFAYGLIDMFWVGGLGSSAVASIGSSSFFLGLGYSINALVVTGTGIKVSHEV
GRKNEIETEDYIRNGLIMNFLIGLIYALILVVFGKGFIGFLNLNDPLVERDSYIYLAVSAPVLFFSFFNYLFTRILASFG
NNKLALKISATGIILNMILDPILIYVFKLGVFGAAVATLLANILMFFMYIYYGKGIFKIDLKKKVNYEKVREIARLGFPM
ASQRVLFTLVNIILARIIASFGADAIAAQKIGLQIESVSFMVVGGLNGAIAGFTGQNYGAKKLNRVNEGYKKALLLGAIY
SILVSALFICIPGLLVGLFVKDEATIIIGSSYLRVLGIVQIFSSFEMISNGVFSGLGLPKIPSAISIIFTMLRIPMALVL
VKFLGINGVWWSIAISNILKGSTSCIIYRLKIYRNYIV

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=346, Percent_Identity=23.4104046242775, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47779; Mature: 47779

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIDLTKGKVLSVLTTLALPIMGSSFLQFAYGLIDMFWVGGLGSSAVASIGSSSFFLGL
CCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEE
GYSINALVVTGTGIKVSHEVGRKNEIETEDYIRNGLIMNFLIGLIYALILVVFGKGFIGF
CCEEEEEEEECCCEEEEHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEE
LNLNDPLVERDSYIYLAVSAPVLFFSFFNYLFTRILASFGNNKLALKISATGIILNMILD
EECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHH
PILIYVFKLGVFGAAVATLLANILMFFMYIYYGKGIFKIDLKKKVNYEKVREIARLGFPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHCCCHHHHHHHHHHCCCC
ASQRVLFTLVNIILARIIASFGADAIAAQKIGLQIESVSFMVVGGLNGAIAGFTGQNYGA
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCEEEEEEEEEEEECCCCCEECCCCCCCCH
KKLNRVNEGYKKALLLGAIYSILVSALFICIPGLLVGLFVKDEATIIIGSSYLRVLGIVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECHHHHHHHHHHH
IFSSFEMISNGVFSGLGLPKIPSAISIIFTMLRIPMALVLVKFLGINGVWWSIAISNILK
HHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GSTSCIIYRLKIYRNYIV
CCCHHEEEEHHHHHHHCC
>Mature Secondary Structure
MKKIDLTKGKVLSVLTTLALPIMGSSFLQFAYGLIDMFWVGGLGSSAVASIGSSSFFLGL
CCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEE
GYSINALVVTGTGIKVSHEVGRKNEIETEDYIRNGLIMNFLIGLIYALILVVFGKGFIGF
CCEEEEEEEECCCEEEEHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEE
LNLNDPLVERDSYIYLAVSAPVLFFSFFNYLFTRILASFGNNKLALKISATGIILNMILD
EECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHH
PILIYVFKLGVFGAAVATLLANILMFFMYIYYGKGIFKIDLKKKVNYEKVREIARLGFPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHCCCHHHHHHHHHHCCCC
ASQRVLFTLVNIILARIIASFGADAIAAQKIGLQIESVSFMVVGGLNGAIAGFTGQNYGA
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCEEEEEEEEEEEECCCCCEECCCCCCCCH
KKLNRVNEGYKKALLLGAIYSILVSALFICIPGLLVGLFVKDEATIIIGSSYLRVLGIVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECHHHHHHHHHHH
IFSSFEMISNGVFSGLGLPKIPSAISIIFTMLRIPMALVLVKFLGINGVWWSIAISNILK
HHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GSTSCIIYRLKIYRNYIV
CCCHHEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]