Click here to switch to the map view.

The map label for this gene is bltR [H]

Identifier: 18309747

GI number: 18309747

Start: 945090

End: 945893

Strand: Direct

Name: bltR [H]

Synonym: CPE0765

Alternate gene names: 18309747

Gene position: 945090-945893 (Clockwise)

Preceding gene: 18309745

Following gene: 18309750

Centisome position: 31.18

GC content: 22.64

Gene sequence:

>804_bases
ATGAAGTTATCTATAGGTGAGGTAGCTAGGTTATTTAATATAAGTAAAGATACATTAAGATACTATGATAAGATAGGAAT
TTTGAAACCAGAGATTAATAAAGAAAATGGTTATAGATTTTATGATATAAGACATTTAGAGCAATTAGGATTAATATTAG
GAATAAAATATTTAGGTATTTCATTAAGTGAAATCAAAGAGATTATAGAAAATGGGGACATAGAGGATTATTATAATTTG
ATGCAAAAGCAAAAAGATATAATAAAAGAGAGGATTCTAGAACTTAAAAAATTAGAGGAATCCTTAGATAATAGTGGACA
AGTAATAAATAGAATAATGAATTTTAAAAATCAGTATGATTTTTCTAAAGTCAATGTAGAAAATTTAGATTTAAAACTCT
ATGAAGTGAAGGTAAGAAGTGCTTTAGACTTAGAGAATGAATCTAAAGTAGAAAAAAAATTAATAGAATTAAAAGATGAA
GCATATTTTTATTTCTATGAAATAAAGGATAATAAACACATTATAGAAGAAGAAAACTTACTTTTTATAAAATCTAATGA
GAATATAGAAAAATTTTTAAAAAAATCAAAGAGTAAAGATAAAATTACCTTTAAAAGCATACAGGGAAAGTTTGCTTTAG
TAGATTTTTATGGAACTGTAGAAGAAATTCATAATTATATACTTAGTATGAATAAATATTTTAAAGGTAATATAGATAAT
TATGCCTTTATAGAATATGAATTTTACTTGCCTAAAAAAAGAGAGGAAGTAAAGTACTTTGTAAGAATATACTTAAGTTT
ATAG

Upstream 100 bases:

>100_bases
GTGGAGTAACTCCAATGTCAATGCCTATTTTGAAAATATATTCATATGGATAATTTAATGAGATATAATTGAATATATAG
TGAGTATAAGAGGTGGGAAT

Downstream 100 bases:

>100_bases
AATAGGTGAATTATTGGCTATTTCAAAATAACTTTTGATATATGACATTATTTAGAGTGAAAAATAATAGTTGAAGAAAA
GGATAAAAATATAACTGGAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MKLSIGEVARLFNISKDTLRYYDKIGILKPEINKENGYRFYDIRHLEQLGLILGIKYLGISLSEIKEIIENGDIEDYYNL
MQKQKDIIKERILELKKLEESLDNSGQVINRIMNFKNQYDFSKVNVENLDLKLYEVKVRSALDLENESKVEKKLIELKDE
AYFYFYEIKDNKHIIEEENLLFIKSNENIEKFLKKSKSKDKITFKSIQGKFALVDFYGTVEEIHNYILSMNKYFKGNIDN
YAFIEYEFYLPKKREEVKYFVRIYLSL

Sequences:

>Translated_267_residues
MKLSIGEVARLFNISKDTLRYYDKIGILKPEINKENGYRFYDIRHLEQLGLILGIKYLGISLSEIKEIIENGDIEDYYNL
MQKQKDIIKERILELKKLEESLDNSGQVINRIMNFKNQYDFSKVNVENLDLKLYEVKVRSALDLENESKVEKKLIELKDE
AYFYFYEIKDNKHIIEEENLLFIKSNENIEKFLKKSKSKDKITFKSIQGKFALVDFYGTVEEIHNYILSMNKYFKGNIDN
YAFIEYEFYLPKKREEVKYFVRIYLSL
>Mature_267_residues
MKLSIGEVARLFNISKDTLRYYDKIGILKPEINKENGYRFYDIRHLEQLGLILGIKYLGISLSEIKEIIENGDIEDYYNL
MQKQKDIIKERILELKKLEESLDNSGQVINRIMNFKNQYDFSKVNVENLDLKLYEVKVRSALDLENESKVEKKLIELKDE
AYFYFYEIKDNKHIIEEENLLFIKSNENIEKFLKKSKSKDKITFKSIQGKFALVDFYGTVEEIHNYILSMNKYFKGNIDN
YAFIEYEFYLPKKREEVKYFVRIYLSL

Specific function: Activates transcription of the blt gene in response to structurally dissimilar drugs [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=107, Percent_Identity=32.7102803738318, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011256
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 32005; Mature: 32005

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSIGEVARLFNISKDTLRYYDKIGILKPEINKENGYRFYDIRHLEQLGLILGIKYLGI
CCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCC
SLSEIKEIIENGDIEDYYNLMQKQKDIIKERILELKKLEESLDNSGQVINRIMNFKNQYD
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
FSKVNVENLDLKLYEVKVRSALDLENESKVEKKLIELKDEAYFYFYEIKDNKHIIEEENL
CCEECHHHCCEEEEEEEEHHHHCCCCHHHHHHHHHHHCCCEEEEEEEEECCCEEECCCCE
LFIKSNENIEKFLKKSKSKDKITFKSIQGKFALVDFYGTVEEIHNYILSMNKYFKGNIDN
EEEECCCCHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCC
YAFIEYEFYLPKKREEVKYFVRIYLSL
EEEEEEEEECCCCHHHHHHHHHHEECC
>Mature Secondary Structure
MKLSIGEVARLFNISKDTLRYYDKIGILKPEINKENGYRFYDIRHLEQLGLILGIKYLGI
CCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCC
SLSEIKEIIENGDIEDYYNLMQKQKDIIKERILELKKLEESLDNSGQVINRIMNFKNQYD
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
FSKVNVENLDLKLYEVKVRSALDLENESKVEKKLIELKDEAYFYFYEIKDNKHIIEEENL
CCEECHHHCCEEEEEEEEHHHHCCCCHHHHHHHHHHHCCCEEEEEEEEECCCEEECCCCE
LFIKSNENIEKFLKKSKSKDKITFKSIQGKFALVDFYGTVEEIHNYILSMNKYFKGNIDN
EEEECCCCHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCC
YAFIEYEFYLPKKREEVKYFVRIYLSL
EEEEEEEEECCCCHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7608059; 8969508; 9384377 [H]