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The map label for this gene is aroE [H]

Identifier: 18309682

GI number: 18309682

Start: 875075

End: 875890

Strand: Direct

Name: aroE [H]

Synonym: CPE0700

Alternate gene names: 18309682

Gene position: 875075-875890 (Clockwise)

Preceding gene: 18309681

Following gene: 18309683

Centisome position: 28.87

GC content: 28.8

Gene sequence:

>816_bases
TTGAAGTTATTTGGATTAATAGGTGAGAAGTTAGGACATAGTTTATCTCCAGAGATACATAATAAAGTTTTTAAAGATAA
TAATATAGATGGATTATATAATCTTTTTTCTGTAAAAAAAGATTTTGAAAATAATATTGTAGAAAGTCTAAAATGCTTAG
GAGTAAAGGGAGCCAATGTTACAATACCATATAAAGAGAAGGTTATGGATCAGCTAGATATTATTTCACATGAGGCCAAA
GTTATAGGAGCAGTAAATACTATTTTAATAAAAGATGGGAAATCCTATGGTTATAACACTGATTATTATGGATTTGGTAA
AATGCTAGAAAGAGCAAAGGTTAATATTGAAGGAAATAGCTTTTTTGTTTTAGGAGCAGGGGGAGCAGCTAGAAGTATTT
TAAAATATTTAGAGGATAGCAAAGCTAAAAAAATAGTTTTGGTTTCTAGGGACAAAGAGAAAGCTTTTAAAAAATTTAAA
GATTTCAATATTAATTTTATGAGTTATGGTGAGCTTGAAGAAATTAATGAAGAGTTTGCGTTAATCAATACAACTCCCTG
TGGAATGTATCCTAATACAAATTCAGTAGCTGTTTCAGAAAAGGTAATTAAAAAGTTTAAGGTTGCTGTGGATATAGTCT
ATAATCCTTTAGAAACTAAGTTTTTAAAAATGGCTAAGGATAATGGTCTTAAAACAGTGGATGGATTATTTATGTTAGTT
GGACAAGGGGTTAAAGCTGAAGAGATTTGGAATGGAATAAAAGTAGATAAGTCTACAGAAGAAGAGATATATGAAGAATT
GAAATGTAGATTTTAA

Upstream 100 bases:

>100_bases
TTATTAAAGTTTAAATCTTAATTATTGTATAGTGTAAGAGTTTTATCTTTATTCAATGTTTTTGTTAGAATTAAATTGTA
AAGATTAAGGAGGTGGAATT

Downstream 100 bases:

>100_bases
AGTTAATTTTGTAATAAGAAAATGTTAATTTGAATACTAAATTTAGCCAAATATGATATAAAATAAGTATAGATTACATT
TTTAAATTATACTTAATTTT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MKLFGLIGEKLGHSLSPEIHNKVFKDNNIDGLYNLFSVKKDFENNIVESLKCLGVKGANVTIPYKEKVMDQLDIISHEAK
VIGAVNTILIKDGKSYGYNTDYYGFGKMLERAKVNIEGNSFFVLGAGGAARSILKYLEDSKAKKIVLVSRDKEKAFKKFK
DFNINFMSYGELEEINEEFALINTTPCGMYPNTNSVAVSEKVIKKFKVAVDIVYNPLETKFLKMAKDNGLKTVDGLFMLV
GQGVKAEEIWNGIKVDKSTEEEIYEELKCRF

Sequences:

>Translated_271_residues
MKLFGLIGEKLGHSLSPEIHNKVFKDNNIDGLYNLFSVKKDFENNIVESLKCLGVKGANVTIPYKEKVMDQLDIISHEAK
VIGAVNTILIKDGKSYGYNTDYYGFGKMLERAKVNIEGNSFFVLGAGGAARSILKYLEDSKAKKIVLVSRDKEKAFKKFK
DFNINFMSYGELEEINEEFALINTTPCGMYPNTNSVAVSEKVIKKFKVAVDIVYNPLETKFLKMAKDNGLKTVDGLFMLV
GQGVKAEEIWNGIKVDKSTEEEIYEELKCRF
>Mature_271_residues
MKLFGLIGEKLGHSLSPEIHNKVFKDNNIDGLYNLFSVKKDFENNIVESLKCLGVKGANVTIPYKEKVMDQLDIISHEAK
VIGAVNTILIKDGKSYGYNTDYYGFGKMLERAKVNIEGNSFFVLGAGGAARSILKYLEDSKAKKIVLVSRDKEKAFKKFK
DFNINFMSYGELEEINEEFALINTTPCGMYPNTNSVAVSEKVIKKFKVAVDIVYNPLETKFLKMAKDNGLKTVDGLFMLV
GQGVKAEEIWNGIKVDKSTEEEIYEELKCRF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=265, Percent_Identity=32.4528301886792, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789675, Length=277, Percent_Identity=32.4909747292419, Blast_Score=113, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320332, Length=269, Percent_Identity=30.4832713754647, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30506; Mature: 30506

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFGLIGEKLGHSLSPEIHNKVFKDNNIDGLYNLFSVKKDFENNIVESLKCLGVKGANV
CCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
TIPYKEKVMDQLDIISHEAKVIGAVNTILIKDGKSYGYNTDYYGFGKMLERAKVNIEGNS
ECCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHEEEECCCE
FFVLGAGGAARSILKYLEDSKAKKIVLVSRDKEKAFKKFKDFNINFMSYGELEEINEEFA
EEEEECCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCEEEECCCHHHHCCCEE
LINTTPCGMYPNTNSVAVSEKVIKKFKVAVDIVYNPLETKFLKMAKDNGLKTVDGLFMLV
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCHHHHHHHHHHCCCCHHHHHHHHHH
GQGVKAEEIWNGIKVDKSTEEEIYEELKCRF
CCCCCHHHHHCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKLFGLIGEKLGHSLSPEIHNKVFKDNNIDGLYNLFSVKKDFENNIVESLKCLGVKGANV
CCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
TIPYKEKVMDQLDIISHEAKVIGAVNTILIKDGKSYGYNTDYYGFGKMLERAKVNIEGNS
ECCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHEEEECCCE
FFVLGAGGAARSILKYLEDSKAKKIVLVSRDKEKAFKKFKDFNINFMSYGELEEINEEFA
EEEEECCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCEEEECCCHHHHCCCEE
LINTTPCGMYPNTNSVAVSEKVIKKFKVAVDIVYNPLETKFLKMAKDNGLKTVDGLFMLV
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCHHHHHHHHHHCCCCHHHHHHHHHH
GQGVKAEEIWNGIKVDKSTEEEIYEELKCRF
CCCCCHHHHHCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA