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The map label for this gene is relA [H]

Identifier: 18309636

GI number: 18309636

Start: 816873

End: 817664

Strand: Direct

Name: relA [H]

Synonym: CPE0654

Alternate gene names: 18309636

Gene position: 816873-817664 (Clockwise)

Preceding gene: 18309635

Following gene: 18309637

Centisome position: 26.95

GC content: 28.79

Gene sequence:

>792_bases
ATGGCTATACAAAATTGGAAAGACTTTTTAACTCCTTATGATCAAGCAGTAAGTGAATTAAAGGTAAAGTTAAGAAGTAT
TAGAAAAGAATTTAGAAGAAAAAATGAATATTCTCCAATCGAGTTTGTAACTGGAAGGGTGAAAGAGGTATCTAGTATAT
TAGAAAAGGCAAATAAATATAGTATTCCTGTAGATAGAATCCAATATGAGATGGAGGATATTGCAGGTATAAGAATAATG
TGCCAATTTGTTGATGATATAGATACTGTTGTCAATATTATAAGGAATAGAAAAGACATGCAAGTTCTTTATGAAAAGGA
CTATGTTAGCAATGTAAAACCAAGTGGCTATAGAAGCTATCATGTGGTTATAAGATATCCTATAAATATGGCAGATGGAC
AAAAAGATATACTTGCTGAATTCCAAATAAGAACTTTAGCAATGAATTTCTGGGCTACAATAGAACATTCTTTAAATTAT
AAGTATAAAAAGAATCTTCCAAAGGACATACAATTTAAATTAAAACGTGCAGCTGATGCAGCATTTACTTTAGATGAAGA
AATGCTTGAAATAAAAGATGAAATAAAGGATGCTCAAACTTTATTTGAGGTTAAATCAGATATTATAAGTACTATAATGA
ATAGTATATTAAATCTTATTTCAATAGGAAAAGTGGCTGAGGCTTCTAGATATCAAATAAGTTTAAATAAACTTATTGAA
GAGGGAGAAGTTTGGGAACTTAATAATTTATTGAGAGCTGTCCAAAGAGACATAGATAAGTATAATGTATAA

Upstream 100 bases:

>100_bases
ATTAAGATTTTGAAATATTTAGTTTTAATACTTTTTTTGGTATAATGAGCGAGGAGAGTTAAATAAATCTCTCTAAGAGA
GTTAGGAAATAGGTGGTTCT

Downstream 100 bases:

>100_bases
TATTTAAATAAAAGTAGTTTTTAATGCCACCTTATTTAAAGGTGGTATTTTTATATAGATATTTAGGAAAAATTAATTTG
GAAAAGAAATTTTATTGTTT

Product: relA/spoT family protein

Products: NA

Alternate protein names: (p)ppGpp synthase yjbM; Small alarmone synthase 1; SAS 1 [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MAIQNWKDFLTPYDQAVSELKVKLRSIRKEFRRKNEYSPIEFVTGRVKEVSSILEKANKYSIPVDRIQYEMEDIAGIRIM
CQFVDDIDTVVNIIRNRKDMQVLYEKDYVSNVKPSGYRSYHVVIRYPINMADGQKDILAEFQIRTLAMNFWATIEHSLNY
KYKKNLPKDIQFKLKRAADAAFTLDEEMLEIKDEIKDAQTLFEVKSDIISTIMNSILNLISIGKVAEASRYQISLNKLIE
EGEVWELNNLLRAVQRDIDKYNV

Sequences:

>Translated_263_residues
MAIQNWKDFLTPYDQAVSELKVKLRSIRKEFRRKNEYSPIEFVTGRVKEVSSILEKANKYSIPVDRIQYEMEDIAGIRIM
CQFVDDIDTVVNIIRNRKDMQVLYEKDYVSNVKPSGYRSYHVVIRYPINMADGQKDILAEFQIRTLAMNFWATIEHSLNY
KYKKNLPKDIQFKLKRAADAAFTLDEEMLEIKDEIKDAQTLFEVKSDIISTIMNSILNLISIGKVAEASRYQISLNKLIE
EGEVWELNNLLRAVQRDIDKYNV
>Mature_262_residues
AIQNWKDFLTPYDQAVSELKVKLRSIRKEFRRKNEYSPIEFVTGRVKEVSSILEKANKYSIPVDRIQYEMEDIAGIRIMC
QFVDDIDTVVNIIRNRKDMQVLYEKDYVSNVKPSGYRSYHVVIRYPINMADGQKDILAEFQIRTLAMNFWATIEHSLNYK
YKKNLPKDIQFKLKRAADAAFTLDEEMLEIKDEIKDAQTLFEVKSDIISTIMNSILNLISIGKVAEASRYQISLNKLIEE
GEVWELNNLLRAVQRDIDKYNV

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. YjbM has probably a

COG id: COG2357

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the relA/spoT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007685 [H]

Pfam domain/function: PF04607 RelA_SpoT [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 30851; Mature: 30720

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQNWKDFLTPYDQAVSELKVKLRSIRKEFRRKNEYSPIEFVTGRVKEVSSILEKANKY
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
SIPVDRIQYEMEDIAGIRIMCQFVDDIDTVVNIIRNRKDMQVLYEKDYVSNVKPSGYRSY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEE
HVVIRYPINMADGQKDILAEFQIRTLAMNFWATIEHSLNYKYKKNLPKDIQFKLKRAADA
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHH
AFTLDEEMLEIKDEIKDAQTLFEVKSDIISTIMNSILNLISIGKVAEASRYQISLNKLIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
EGEVWELNNLLRAVQRDIDKYNV
CCCEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIQNWKDFLTPYDQAVSELKVKLRSIRKEFRRKNEYSPIEFVTGRVKEVSSILEKANKY
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
SIPVDRIQYEMEDIAGIRIMCQFVDDIDTVVNIIRNRKDMQVLYEKDYVSNVKPSGYRSY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEE
HVVIRYPINMADGQKDILAEFQIRTLAMNFWATIEHSLNYKYKKNLPKDIQFKLKRAADA
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHH
AFTLDEEMLEIKDEIKDAQTLFEVKSDIISTIMNSILNLISIGKVAEASRYQISLNKLIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
EGEVWELNNLLRAVQRDIDKYNV
CCCEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]