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The map label for this gene is apeB [H]

Identifier: 18309589

GI number: 18309589

Start: 760607

End: 761902

Strand: Direct

Name: apeB [H]

Synonym: CPE0607

Alternate gene names: 18309589

Gene position: 760607-761902 (Clockwise)

Preceding gene: 18309588

Following gene: 18309591

Centisome position: 25.09

GC content: 29.63

Gene sequence:

>1296_bases
ATGGAAAAAGTTATTGCAAATGAATTAATTAATTTTTTATATGAAAGTCCAACAGCTTTTCATGCAGTAAAGAATGTTAA
GGACACTTTAGAATTTGAAGGCTTTAAAGAATTAAAAGAGGCTGATAGATGGAACTTAGAAGTAGAAGGAAAGTATTTTG
TAACTAAAAATGATTCAGCTTTAATTGCTTTTAGAGTTGGTAAAGGTGATATTGCTGAAAATGGATTTAAAATAATTGGT
GCTCATACTGATTCACCAGGATTTAGAATAAAACCAAATCCAGAGATTACAGTTGAAAATACTTATGTAAAATTAAATAC
AGAAGTTTACGGAGGACCAATACTAAATACTTGGTTTGATAGACCACTAGCTTTAGCTGGAAGAGTATCATTAGTAAGTA
AAAATCCATTAAACCCAGTAAATAAGATAGTTAATATAAATAGACCTATTCTTATAATTCCAAACTTAGCTATTCATATG
AATAGAGAAGTTAATGAGGGATATAAAATAAATAGACAAAAGGATACATTACCTTTATTATCACTTGTTAATGAAACTTT
AGAAAAAGGTAATTATTTAGTTGAACTTTTAGCAAAAGAATTATATTGTGAAAAAGAGGATATTCTTGATTTTGAATTAT
ATCCATATGAATATGAAAAAGGTTGCTTAATGGGATTAAATGAAGAGTTTATATCTTCAGGAAGATTAGATGATTTATCA
ATGGTTCATGCAGGTATTAAAGCATTAATGGATGCTGAGGTATCACAAGCTACTAATGTAATGGTATGTTTTGATAATGA
AGAGGTTGGAAGTGCTACTAAACAAGGTGGAGATTCAGATTTCTTAAAAACAATATTAGAAAGAATAGTCCTAGCTTTAG
GTAAAGATAGAGAGGATTTCTTAAGATCATTATCAGAATCATTTATGATTTCAGCAGATTTAGCTCATGCTGTTCATCCA
AATTTAGGAGAAAAACACGATCCTGTAGTTAGACCTGTTTTAGGAAAAGGACCTGTAATAAAAATAGCAGCATCACAAAG
CTATACAAGTGATAGTGATTCATCAGCTGTTTATGAAATGATATGTAGAAATGCAGGAGTTAATGTTCAAAAGTTTGTTA
ATAGATCAGATATGAGAGGTGGTTCAACTATAGGACCAATATCATCAACTCATTTACCAATAAGATCAGTTGACATGGGA
ACTCCAATATTAGCAATGCATTCAATAAGAGAGTTTGGTGCTGTTAAAGATCATTTTGATTGTATAAAGTCATTCACTGA
ATTCTTTAGAATTTAG

Upstream 100 bases:

>100_bases
AGGAAGTACTTTTTGGATAACTTTAAGATTTTGTTAATTATGGATTTTGTGGTAAAGTATAATTAAAAGTATCTATTTTA
TACAGAAAGGTGAGATACAT

Downstream 100 bases:

>100_bases
TCTATTAATAATTTTCAATATATTTAGTTAATATAATTTTTATTAATTATAACAAAAGTGGGATGTAGAAATTTACATCC
CATTTTTTATATTTAAATAT

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MEKVIANELINFLYESPTAFHAVKNVKDTLEFEGFKELKEADRWNLEVEGKYFVTKNDSALIAFRVGKGDIAENGFKIIG
AHTDSPGFRIKPNPEITVENTYVKLNTEVYGGPILNTWFDRPLALAGRVSLVSKNPLNPVNKIVNINRPILIIPNLAIHM
NREVNEGYKINRQKDTLPLLSLVNETLEKGNYLVELLAKELYCEKEDILDFELYPYEYEKGCLMGLNEEFISSGRLDDLS
MVHAGIKALMDAEVSQATNVMVCFDNEEVGSATKQGGDSDFLKTILERIVLALGKDREDFLRSLSESFMISADLAHAVHP
NLGEKHDPVVRPVLGKGPVIKIAASQSYTSDSDSSAVYEMICRNAGVNVQKFVNRSDMRGGSTIGPISSTHLPIRSVDMG
TPILAMHSIREFGAVKDHFDCIKSFTEFFRI

Sequences:

>Translated_431_residues
MEKVIANELINFLYESPTAFHAVKNVKDTLEFEGFKELKEADRWNLEVEGKYFVTKNDSALIAFRVGKGDIAENGFKIIG
AHTDSPGFRIKPNPEITVENTYVKLNTEVYGGPILNTWFDRPLALAGRVSLVSKNPLNPVNKIVNINRPILIIPNLAIHM
NREVNEGYKINRQKDTLPLLSLVNETLEKGNYLVELLAKELYCEKEDILDFELYPYEYEKGCLMGLNEEFISSGRLDDLS
MVHAGIKALMDAEVSQATNVMVCFDNEEVGSATKQGGDSDFLKTILERIVLALGKDREDFLRSLSESFMISADLAHAVHP
NLGEKHDPVVRPVLGKGPVIKIAASQSYTSDSDSSAVYEMICRNAGVNVQKFVNRSDMRGGSTIGPISSTHLPIRSVDMG
TPILAMHSIREFGAVKDHFDCIKSFTEFFRI
>Mature_431_residues
MEKVIANELINFLYESPTAFHAVKNVKDTLEFEGFKELKEADRWNLEVEGKYFVTKNDSALIAFRVGKGDIAENGFKIIG
AHTDSPGFRIKPNPEITVENTYVKLNTEVYGGPILNTWFDRPLALAGRVSLVSKNPLNPVNKIVNINRPILIIPNLAIHM
NREVNEGYKINRQKDTLPLLSLVNETLEKGNYLVELLAKELYCEKEDILDFELYPYEYEKGCLMGLNEEFISSGRLDDLS
MVHAGIKALMDAEVSQATNVMVCFDNEEVGSATKQGGDSDFLKTILERIVLALGKDREDFLRSLSESFMISADLAHAVHP
NLGEKHDPVVRPVLGKGPVIKIAASQSYTSDSDSSAVYEMICRNAGVNVQKFVNRSDMRGGSTIGPISSTHLPIRSVDMG
TPILAMHSIREFGAVKDHFDCIKSFTEFFRI

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=452, Percent_Identity=38.0530973451327, Blast_Score=308, Evalue=9e-84,
Organism=Caenorhabditis elegans, GI17552916, Length=450, Percent_Identity=36.4444444444444, Blast_Score=283, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6321905, Length=459, Percent_Identity=40.5228758169935, Blast_Score=325, Evalue=9e-90,
Organism=Saccharomyces cerevisiae, GI6322746, Length=455, Percent_Identity=29.010989010989, Blast_Score=190, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 48112; Mature: 48112

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVIANELINFLYESPTAFHAVKNVKDTLEFEGFKELKEADRWNLEVEGKYFVTKNDSA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEECCEEEEEECCCE
LIAFRVGKGDIAENGFKIIGAHTDSPGFRIKPNPEITVENTYVKLNTEVYGGPILNTWFD
EEEEEECCCCCCCCCCEEEEEECCCCCEEECCCCCEEEEEEEEEEECEECCCCCHHHHHC
RPLALAGRVSLVSKNPLNPVNKIVNINRPILIIPNLAIHMNREVNEGYKINRQKDTLPLL
CCHHHHCEEEEECCCCCCHHHHHHCCCCCEEEECCEEEEECCCCCCCEEECCCCCHHHHH
SLVNETLEKGNYLVELLAKELYCEKEDILDFELYPYEYEKGCLMGLNEEFISSGRLDDLS
HHHHHHHHCCHHHHHHHHHHHCCCHHCCEEEEECCCCCCCCCEECCCHHHHCCCCCCHHH
MVHAGIKALMDAEVSQATNVMVCFDNEEVGSATKQGGDSDFLKTILERIVLALGKDREDF
HHHHHHHHHHHHHHHHHCEEEEEECCCHHCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
LRSLSESFMISADLAHAVHPNLGEKHDPVVRPVLGKGPVIKIAASQSYTSDSDSSAVYEM
HHHHHHHHEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
ICRNAGVNVQKFVNRSDMRGGSTIGPISSTHLPIRSVDMGTPILAMHSIREFGAVKDHFD
HHHCCCCCHHHHHCHHCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCHHHHHH
CIKSFTEFFRI
HHHHHHHHHCC
>Mature Secondary Structure
MEKVIANELINFLYESPTAFHAVKNVKDTLEFEGFKELKEADRWNLEVEGKYFVTKNDSA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEECCEEEEEECCCE
LIAFRVGKGDIAENGFKIIGAHTDSPGFRIKPNPEITVENTYVKLNTEVYGGPILNTWFD
EEEEEECCCCCCCCCCEEEEEECCCCCEEECCCCCEEEEEEEEEEECEECCCCCHHHHHC
RPLALAGRVSLVSKNPLNPVNKIVNINRPILIIPNLAIHMNREVNEGYKINRQKDTLPLL
CCHHHHCEEEEECCCCCCHHHHHHCCCCCEEEECCEEEEECCCCCCCEEECCCCCHHHHH
SLVNETLEKGNYLVELLAKELYCEKEDILDFELYPYEYEKGCLMGLNEEFISSGRLDDLS
HHHHHHHHCCHHHHHHHHHHHCCCHHCCEEEEECCCCCCCCCEECCCHHHHCCCCCCHHH
MVHAGIKALMDAEVSQATNVMVCFDNEEVGSATKQGGDSDFLKTILERIVLALGKDREDF
HHHHHHHHHHHHHHHHHCEEEEEECCCHHCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHH
LRSLSESFMISADLAHAVHPNLGEKHDPVVRPVLGKGPVIKIAASQSYTSDSDSSAVYEM
HHHHHHHHEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
ICRNAGVNVQKFVNRSDMRGGSTIGPISSTHLPIRSVDMGTPILAMHSIREFGAVKDHFD
HHHCCCCCHHHHHCHHCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCHHHHHH
CIKSFTEFFRI
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]