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The map label for this gene is glsA1

Identifier: 18309573

GI number: 18309573

Start: 733374

End: 734297

Strand: Direct

Name: glsA1

Synonym: CPE0591

Alternate gene names: 18309573

Gene position: 733374-734297 (Clockwise)

Preceding gene: 18309572

Following gene: 18309574

Centisome position: 24.19

GC content: 29.0

Gene sequence:

>924_bases
ATGGATATAAATTTAGATGCTTTAGTAGAAGCTAATAGAAGATATACAAAAGAAGGACATGTAGCTACATATATTCCAGC
CCTTGCAAAGGTAAATCCAGATCAATTAGGTGTTTGTATTTATGATTTAAAAGAAAATAAAGAATTTTCAGCTGGAGAAT
ATGATGTTAGGTTTGCAATTGAAAGCATATCAAAGGTTCCTACATTAATATTAGCTATATTAGATAATGGAATAGAAAAA
GTATTTTCAGAAGTTGGAACAGAACCTTCTGGATTTGCTTTTAATTCAATTATGAATATGCAAATAAATCATAAAAATAA
ACCATCAAACCCATTTATTAATGCAGGAGCTATTAAAGTAGTATCCTTACTTAAAGGGAAAAATGATGAAGAACGTTTTA
AAAGAATTTTAGATTTTTATAGAAAGATTATGAATGATGATGAAATTACTTTAGATACTGAAATATATTTATCAGAAAGA
GAAACAGGTGATATAAACAGATCTCTTGCTTATTATATGAAGGGTAATGGAATCATGGAAGGTGATGTTACTGATATTTT
AGATTCATATTTTAAACAATGTTCAGTTTTAGTTACAGCTAAGGATTTAGCAAGATTAGGTGCTGTATTAGCTAATGAAG
GGGTTATGCCTTGGAATGGTGAAAGATTATTTTCTGTAGAAACAGCTACTGTTGTTAAATCATTAATGACTACTTACGGA
TTATATGATGAATCAGGAGCTTTTTCAGTTCATATTGGACTACCATCTAAAAGTGGTGTAGGAGGAGGAATATTATCTTC
AGTTCCTAATAAATGTGGTATAGGATTATTTAGTCCAGCTTTAGATGTATCAGGAAATAGTGTTGCTAGTATGAAACTTC
TAAAGGAAATAGCAGATAAATTAAAATTAGATATATTTAGATAG

Upstream 100 bases:

>100_bases
ACCTATAGAAAAATTATATGAAGTAAAATTTTTGAGTTTTGATTTTGAAATTATTAACTGTTTATAATATTTTTAGAAGA
TAAATTTAGAGGTGATTTAT

Downstream 100 bases:

>100_bases
AAGTTTTTAAATAAGTAAATTAGGTTTAAGTATGTTTAGAGTGATTAAAAATCTAAATATATTTAAGCCTATATTTTTTA
TTTTAACAACTATTTTATGG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDINLDALVEANRRYTKEGHVATYIPALAKVNPDQLGVCIYDLKENKEFSAGEYDVRFAIESISKVPTLILAILDNGIEK
VFSEVGTEPSGFAFNSIMNMQINHKNKPSNPFINAGAIKVVSLLKGKNDEERFKRILDFYRKIMNDDEITLDTEIYLSER
ETGDINRSLAYYMKGNGIMEGDVTDILDSYFKQCSVLVTAKDLARLGAVLANEGVMPWNGERLFSVETATVVKSLMTTYG
LYDESGAFSVHIGLPSKSGVGGGILSSVPNKCGIGLFSPALDVSGNSVASMKLLKEIADKLKLDIFR

Sequences:

>Translated_307_residues
MDINLDALVEANRRYTKEGHVATYIPALAKVNPDQLGVCIYDLKENKEFSAGEYDVRFAIESISKVPTLILAILDNGIEK
VFSEVGTEPSGFAFNSIMNMQINHKNKPSNPFINAGAIKVVSLLKGKNDEERFKRILDFYRKIMNDDEITLDTEIYLSER
ETGDINRSLAYYMKGNGIMEGDVTDILDSYFKQCSVLVTAKDLARLGAVLANEGVMPWNGERLFSVETATVVKSLMTTYG
LYDESGAFSVHIGLPSKSGVGGGILSSVPNKCGIGLFSPALDVSGNSVASMKLLKEIADKLKLDIFR
>Mature_307_residues
MDINLDALVEANRRYTKEGHVATYIPALAKVNPDQLGVCIYDLKENKEFSAGEYDVRFAIESISKVPTLILAILDNGIEK
VFSEVGTEPSGFAFNSIMNMQINHKNKPSNPFINAGAIKVVSLLKGKNDEERFKRILDFYRKIMNDDEITLDTEIYLSER
ETGDINRSLAYYMKGNGIMEGDVTDILDSYFKQCSVLVTAKDLARLGAVLANEGVMPWNGERLFSVETATVVKSLMTTYG
LYDESGAFSVHIGLPSKSGVGGGILSSVPNKCGIGLFSPALDVSGNSVASMKLLKEIADKLKLDIFR

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=297, Percent_Identity=40.7407407407407, Blast_Score=211, Evalue=9e-55,
Organism=Homo sapiens, GI20336214, Length=272, Percent_Identity=39.7058823529412, Blast_Score=184, Evalue=9e-47,
Organism=Escherichia coli, GI1786693, Length=289, Percent_Identity=40.1384083044983, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1787804, Length=302, Percent_Identity=36.7549668874172, Blast_Score=204, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17507019, Length=290, Percent_Identity=41.0344827586207, Blast_Score=210, Evalue=8e-55,
Organism=Caenorhabditis elegans, GI17532727, Length=285, Percent_Identity=41.7543859649123, Blast_Score=205, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI193204073, Length=298, Percent_Identity=36.5771812080537, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI193204075, Length=300, Percent_Identity=36, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653164, Length=286, Percent_Identity=37.0629370629371, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24653158, Length=286, Percent_Identity=37.0629370629371, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24653162, Length=286, Percent_Identity=37.0629370629371, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI281363239, Length=286, Percent_Identity=37.0629370629371, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI116008307, Length=286, Percent_Identity=37.0629370629371, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24653156, Length=286, Percent_Identity=37.0629370629371, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI281363241, Length=286, Percent_Identity=37.0629370629371, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24653166, Length=286, Percent_Identity=37.0629370629371, Blast_Score=187, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA1_CLOPE (Q8XMU7)

Other databases:

- EMBL:   BA000016
- RefSeq:   NP_561507.1
- ProteinModelPortal:   Q8XMU7
- SMR:   Q8XMU7
- GeneID:   988845
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE0591
- NMPDR:   fig|195102.1.peg.654
- HOGENOM:   HBG512335
- OMA:   YLSERET
- PhylomeDB:   Q8XMU7
- ProtClustDB:   CLSK518681
- BioCyc:   CPER195102:CPE0591-MONOMER
- BRENDA:   3.5.1.2
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 33731; Mature: 33731

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINLDALVEANRRYTKEGHVATYIPALAKVNPDQLGVCIYDLKENKEFSAGEYDVRFAI
CCCCHHHHHHCCHHCCCCCCCHHHHHHHHCCCHHHHCEEEEEECCCCCCCCCCCHHHHHH
ESISKVPTLILAILDNGIEKVFSEVGTEPSGFAFNSIMNMQINHKNKPSNPFINAGAIKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHEEEEEEECCCCCCCCCCCCHHHHH
VSLLKGKNDEERFKRILDFYRKIMNDDEITLDTEIYLSERETGDINRSLAYYMKGNGIME
HHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCEEEEEECCCEEC
GDVTDILDSYFKQCSVLVTAKDLARLGAVLANEGVMPWNGERLFSVETATVVKSLMTTYG
CCHHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHC
LYDESGAFSVHIGLPSKSGVGGGILSSVPNKCGIGLFSPALDVSGNSVASMKLLKEIADK
CCCCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LKLDIFR
HHCCCCC
>Mature Secondary Structure
MDINLDALVEANRRYTKEGHVATYIPALAKVNPDQLGVCIYDLKENKEFSAGEYDVRFAI
CCCCHHHHHHCCHHCCCCCCCHHHHHHHHCCCHHHHCEEEEEECCCCCCCCCCCHHHHHH
ESISKVPTLILAILDNGIEKVFSEVGTEPSGFAFNSIMNMQINHKNKPSNPFINAGAIKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHEEEEEEECCCCCCCCCCCCHHHHH
VSLLKGKNDEERFKRILDFYRKIMNDDEITLDTEIYLSERETGDINRSLAYYMKGNGIME
HHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCEEEEEECCCEEC
GDVTDILDSYFKQCSVLVTAKDLARLGAVLANEGVMPWNGERLFSVETATVVKSLMTTYG
CCHHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHC
LYDESGAFSVHIGLPSKSGVGGGILSSVPNKCGIGLFSPALDVSGNSVASMKLLKEIADK
CCCCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LKLDIFR
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842