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The map label for this gene is fabA

Identifier: 182682181

GI number: 182682181

Start: 1837737

End: 1838255

Strand: Direct

Name: fabA

Synonym: XfasM23_1660

Alternate gene names: 182682181

Gene position: 1837737-1838255 (Clockwise)

Preceding gene: 182682178

Following gene: 182682182

Centisome position: 72.47

GC content: 51.25

Gene sequence:

>519_bases
ATGTCCCGGCAACATGCGTATTCACGCGAAGAACTGCTGGCAACCGCGCGTGGCGAACTCTTCAGTCACAGCAACGCCCG
CCTGCCGAATGATCCAATGCTGATGTTTGACAGAATCACCGAAATTTATGCAGACGGCGGCTCACACGGTAAGGGTATCG
TCAATGCGGAACTTGATATTCGGCCAGACTTGTGGTTCTTCGGTTGTCATTTCCTCGGTGACCCAGTGATGCCTGGCTGT
CTCGGCCTGGACGCCATGTGGCAACTCACCGGTTTTTTTCTAACATGGAGCGGCGCAACCCCCGGATACGGTCGTGCATT
GGGCTGTGGCGAAGTCAAGTTCACAGGTCAAGTACTGCCAAACGCAAAATTGGTGCGTTACGAAGTAGAGATGACCAAAA
TCATCAACCGCACACTGGTCATTGGTCAGGCTAATGCCCGGATGTTGGTAGATAATCGTGAGATATATTTCGCCAAAGAC
CTACGCGTAGGTATGTTCAACAACACAGAATCTTTTTAG

Upstream 100 bases:

>100_bases
CACATCACATCACAGCTGAAATACACATCGTCATGTTTGATTGCATCCGCATTGCTCAGGTACGCTTACTTCCCTTTATG
GGCTAGACGCAGGAATTTTG

Downstream 100 bases:

>100_bases
GGCACCGCGTTGTAGCACCTGGATGGAAATCGAATTGTCGCCCCTCCTTCTGCTCGGGCGGCATATTTCCCACAACACAA
AACGCAGCGTGATCGACCGA

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MSRQHAYSREELLATARGELFSHSNARLPNDPMLMFDRITEIYADGGSHGKGIVNAELDIRPDLWFFGCHFLGDPVMPGC
LGLDAMWQLTGFFLTWSGATPGYGRALGCGEVKFTGQVLPNAKLVRYEVEMTKIINRTLVIGQANARMLVDNREIYFAKD
LRVGMFNNTESF

Sequences:

>Translated_172_residues
MSRQHAYSREELLATARGELFSHSNARLPNDPMLMFDRITEIYADGGSHGKGIVNAELDIRPDLWFFGCHFLGDPVMPGC
LGLDAMWQLTGFFLTWSGATPGYGRALGCGEVKFTGQVLPNAKLVRYEVEMTKIINRTLVIGQANARMLVDNREIYFAKD
LRVGMFNNTESF
>Mature_171_residues
SRQHAYSREELLATARGELFSHSNARLPNDPMLMFDRITEIYADGGSHGKGIVNAELDIRPDLWFFGCHFLGDPVMPGCL
GLDAMWQLTGFFLTWSGATPGYGRALGCGEVKFTGQVLPNAKLVRYEVEMTKIINRTLVIGQANARMLVDNREIYFAKDL
RVGMFNNTESF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily

Homologues:

Organism=Escherichia coli, GI1787187, Length=172, Percent_Identity=58.1395348837209, Blast_Score=215, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABA_XYLF2 (B2I7H0)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830341.1
- ProteinModelPortal:   B2I7H0
- SMR:   B2I7H0
- GeneID:   6202798
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1660
- HOGENOM:   HBG433282
- OMA:   CHFKGDP
- ProtClustDB:   PRK05174
- GO:   GO:0005737
- HAMAP:   MF_00405
- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114
- PANTHER:   PTHR11712
- TIGRFAMs:   TIGR01749

Pfam domain/function: PF07977 FabA

EC number: =4.2.1.60

Molecular weight: Translated: 19285; Mature: 19154

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 70-70

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQHAYSREELLATARGELFSHSNARLPNDPMLMFDRITEIYADGGSHGKGIVNAELDI
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEC
RPDLWFFGCHFLGDPVMPGCLGLDAMWQLTGFFLTWSGATPGYGRALGCGEVKFTGQVLP
CCCEEEEEHHHCCCCCCCCHHCHHHHHHEEEEEEEECCCCCCCCCEECCCCEEEECEECC
NAKLVRYEVEMTKIINRTLVIGQANARMLVDNREIYFAKDLRVGMFNNTESF
CCEEEEEEHHHHHHHCEEEEEECCCCEEEEECCEEEEEECEEEEECCCCCCC
>Mature Secondary Structure 
SRQHAYSREELLATARGELFSHSNARLPNDPMLMFDRITEIYADGGSHGKGIVNAELDI
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEC
RPDLWFFGCHFLGDPVMPGCLGLDAMWQLTGFFLTWSGATPGYGRALGCGEVKFTGQVLP
CCCEEEEEHHHCCCCCCCCHHCHHHHHHEEEEEEEECCCCCCCCCEECCCCEEEECEECC
NAKLVRYEVEMTKIINRTLVIGQANARMLVDNREIYFAKDLRVGMFNNTESF
CCEEEEEEHHHHHHHCEEEEEECCCCEEEEECCEEEEEECEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA