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The map label for this gene is folE2 [H]

Identifier: 182681377

GI number: 182681377

Start: 971488

End: 972387

Strand: Direct

Name: folE2 [H]

Synonym: XfasM23_0825

Alternate gene names: 182681377

Gene position: 971488-972387 (Clockwise)

Preceding gene: 182681376

Following gene: 182681378

Centisome position: 38.31

GC content: 53.56

Gene sequence:

>900_bases
ATGATGTCCACTTCTATTCCTGATGTTGCTGTTCATGACAGCCCCGCAATCGCTGCGCCGTTGCGTTGGGTTGGCATGGA
TGGAATCGTAGTACCAGTACAGTTGACGACAGCCGATGGTGGCCAACATGTGATTGGACGTGCTAGAGCACAGATTGATT
TACCTGCGATGGGAGTCAAAGGGATTCATATGTCGCGCTTGTATCGCCTGTTGGATACGTATGCGGTTGAGCCACTGACA
CCGGTGGGTATTTGCGGATTGCTCTCCGCGATGGTGAATAGTCATGCTGATTGTGCGTCTACCGCCGCGCGTGTGGATTG
GTATTTCGATTGGCTGCGACGTGTGCCGGCGTTGGTGAGTAACGATTTGTCTGGTTGGCGTGGCTATCCGGTGTGGTTGC
GTGCCGAATATTCTGCTGGGCACGTCCAATTCTGGTTGTGTGTGGAGGTCGCATATTCGTCGACGTGTCCTTGTTCGGCG
GCATTAGCGCGGCAGATGTTGGCCGATGCATTTCTACAAGAACACGTGGAGGTGTCTGCATTGTCGCCTGAGACTGTTGC
TGATTGGTTGCGCTCCAATGGTTCGTATGCCACACCACACAGTCAGCGTAGCCTGGCACGTATTGAGGTTGCACTCACTG
AGCAGGCAGTTGAATTGGGGCTTCCTGCATTAGTCGACTGTGCCGAGCGCATCTTGTCCACGCCTGTACAGGCAGCGGTA
CGACGTGTCGATGAACAGGCGTTTGCTCGTCTCAATGGCGCTAACTTGATGTACGTGGAAGATGCTACGCGCCGTTTGCA
ACACGGATTAGCAATCCATTATTCCGCTTTCAGGGTACATGTCAGGCACTTGGAGAGCTTGCATCCTAATGATGCGGTTG
CCAGTACCGCAGATGAGTGA

Upstream 100 bases:

>100_bases
GGTTGAGAGCGGCTTCATGCGTGATACCGATGACTATCGACGTTCGATCTGTGGCTTGTGCAGGTGAGATTTTTTCCATG
ATGTATGTTGCGAGTTCTCA

Downstream 100 bases:

>100_bases
TCGAACTGATCTATGTTCAACTCAACAGGCATGCAGTAGCCCTTTCTGATTCTCACCACAACCGCTGTCATATGATCCGT
AAAAATCCGCGGGGAGACCT

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MMSTSIPDVAVHDSPAIAAPLRWVGMDGIVVPVQLTTADGGQHVIGRARAQIDLPAMGVKGIHMSRLYRLLDTYAVEPLT
PVGICGLLSAMVNSHADCASTAARVDWYFDWLRRVPALVSNDLSGWRGYPVWLRAEYSAGHVQFWLCVEVAYSSTCPCSA
ALARQMLADAFLQEHVEVSALSPETVADWLRSNGSYATPHSQRSLARIEVALTEQAVELGLPALVDCAERILSTPVQAAV
RRVDEQAFARLNGANLMYVEDATRRLQHGLAIHYSAFRVHVRHLESLHPNDAVASTADE

Sequences:

>Translated_299_residues
MMSTSIPDVAVHDSPAIAAPLRWVGMDGIVVPVQLTTADGGQHVIGRARAQIDLPAMGVKGIHMSRLYRLLDTYAVEPLT
PVGICGLLSAMVNSHADCASTAARVDWYFDWLRRVPALVSNDLSGWRGYPVWLRAEYSAGHVQFWLCVEVAYSSTCPCSA
ALARQMLADAFLQEHVEVSALSPETVADWLRSNGSYATPHSQRSLARIEVALTEQAVELGLPALVDCAERILSTPVQAAV
RRVDEQAFARLNGANLMYVEDATRRLQHGLAIHYSAFRVHVRHLESLHPNDAVASTADE
>Mature_299_residues
MMSTSIPDVAVHDSPAIAAPLRWVGMDGIVVPVQLTTADGGQHVIGRARAQIDLPAMGVKGIHMSRLYRLLDTYAVEPLT
PVGICGLLSAMVNSHADCASTAARVDWYFDWLRRVPALVSNDLSGWRGYPVWLRAEYSAGHVQFWLCVEVAYSSTCPCSA
ALARQMLADAFLQEHVEVSALSPETVADWLRSNGSYATPHSQRSLARIEVALTEQAVELGLPALVDCAERILSTPVQAAV
RRVDEQAFARLNGANLMYVEDATRRLQHGLAIHYSAFRVHVRHLESLHPNDAVASTADE

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: =3.5.4.16 [H]

Molecular weight: Translated: 32648; Mature: 32648

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSTSIPDVAVHDSPAIAAPLRWVGMDGIVVPVQLTTADGGQHVIGRARAQIDLPAMGVK
CCCCCCCCEEECCCCCHHCCHHEECCCCEEEEEEEEECCCCHHHHHHHHHEECCCCCCCC
GIHMSRLYRLLDTYAVEPLTPVGICGLLSAMVNSHADCASTAARVDWYFDWLRRVPALVS
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
NDLSGWRGYPVWLRAEYSAGHVQFWLCVEVAYSSTCPCSAALARQMLADAFLQEHVEVSA
CCCCCCCCCCEEEEEECCCCCEEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
LSPETVADWLRSNGSYATPHSQRSLARIEVALTEQAVELGLPALVDCAERILSTPVQAAV
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
RRVDEQAFARLNGANLMYVEDATRRLQHGLAIHYSAFRVHVRHLESLHPNDAVASTADE
HHHHHHHHHHHCCCEEEEEHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MMSTSIPDVAVHDSPAIAAPLRWVGMDGIVVPVQLTTADGGQHVIGRARAQIDLPAMGVK
CCCCCCCCEEECCCCCHHCCHHEECCCCEEEEEEEEECCCCHHHHHHHHHEECCCCCCCC
GIHMSRLYRLLDTYAVEPLTPVGICGLLSAMVNSHADCASTAARVDWYFDWLRRVPALVS
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
NDLSGWRGYPVWLRAEYSAGHVQFWLCVEVAYSSTCPCSAALARQMLADAFLQEHVEVSA
CCCCCCCCCCEEEEEECCCCCEEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
LSPETVADWLRSNGSYATPHSQRSLARIEVALTEQAVELGLPALVDCAERILSTPVQAAV
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
RRVDEQAFARLNGANLMYVEDATRRLQHGLAIHYSAFRVHVRHLESLHPNDAVASTADE
HHHHHHHHHHHCCCEEEEEHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA