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The map label for this gene is moeZ [H]

Identifier: 182680529

GI number: 182680529

Start: 4118819

End: 4119607

Strand: Reverse

Name: moeZ [H]

Synonym: Bind_3634

Alternate gene names: 182680529

Gene position: 4119607-4118819 (Counterclockwise)

Preceding gene: 182680530

Following gene: 182680528

Centisome position: 98.79

GC content: 61.98

Gene sequence:

>789_bases
ATGGTGGCTGTGCTTTCACCCGAAGAAATTGAGCGCTATGGCCGCCATATCCTGCTTCGCGATATTGGTGGCCAGGGCCA
ACAGAAACTCAAGGCGGCGCGCGTCCTCGTCATCGGCGCCGGGGGGCTCGGCTCACCGCTCATTCAATATCTCGCCGCCG
CCGGCCTCGGTGAAATCGGCGTGGTCGATGACGATGCCGTGTCTCTTTCAAATCTCCAGCGCCAGATTCTCCATGGGACG
CCGGATCTCGGCCGCCCGAAGGTCGAAAGTGCGCAAGAGGCCGTGCGTCGATTGAACCCGCATGTGGTCCTGACCCCCTT
CCCCACGCGATTGAACGGGACGAATGCGCGTGGCCTGATCGAGGCCTATGACATTGTCGCCGATGGGTCGGATAATTTCG
CAACGCGCTATCTGGCGTCCGATCTCTGTTTTCATGCCAAACGCCCGCTCGTGACGGGTGCCGTCGGCGCGTTCGACGGC
TCTCTAACGACCTTGCGGCCATTCGAAACCGGTCCCGACGGCCATCCGAACCCGACCTATCGCTGTCTGTTTCCCGAACC
GCCGCCGGACGGCACAGTGCCGACCTGTGAAGAGGCAGGCGTGCTTGGTGCGCTCACGGGGATGCTCGGCGCGATGATGG
CGCTTGAAGTGATCCGCGAGATTGTCGGCTTCGGCGAAGGCCTCGTCGGACGCCTCCTTCTGGTCGATGCCTTGCATCTG
CGTTTCGAAACTTTGAATTACCGCTGGGATCCGTCCAATCCGCTGAATGGCGAGCCTCGCGCGGCGTAA

Upstream 100 bases:

>100_bases
CTTTCTGCTGCAGCGGAGGATGCCCTCCGTCACTTTGTTTTAATGCATAATCCTGTCTCAAAACTCCTCCTCCGAGGGTT
ATGCTTGATGCGAGACATGA

Downstream 100 bases:

>100_bases
CGAGCGCCGAGCGAGCAGCGGCACATCTGATGGTCGTTCTCTACGACGATCGATACCAGCGTGGACCGAATGTCTTTTGA
TGCAGGATGGTGCATGGCTT

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MVAVLSPEEIERYGRHILLRDIGGQGQQKLKAARVLVIGAGGLGSPLIQYLAAAGLGEIGVVDDDAVSLSNLQRQILHGT
PDLGRPKVESAQEAVRRLNPHVVLTPFPTRLNGTNARGLIEAYDIVADGSDNFATRYLASDLCFHAKRPLVTGAVGAFDG
SLTTLRPFETGPDGHPNPTYRCLFPEPPPDGTVPTCEEAGVLGALTGMLGAMMALEVIREIVGFGEGLVGRLLLVDALHL
RFETLNYRWDPSNPLNGEPRAA

Sequences:

>Translated_262_residues
MVAVLSPEEIERYGRHILLRDIGGQGQQKLKAARVLVIGAGGLGSPLIQYLAAAGLGEIGVVDDDAVSLSNLQRQILHGT
PDLGRPKVESAQEAVRRLNPHVVLTPFPTRLNGTNARGLIEAYDIVADGSDNFATRYLASDLCFHAKRPLVTGAVGAFDG
SLTTLRPFETGPDGHPNPTYRCLFPEPPPDGTVPTCEEAGVLGALTGMLGAMMALEVIREIVGFGEGLVGRLLLVDALHL
RFETLNYRWDPSNPLNGEPRAA
>Mature_262_residues
MVAVLSPEEIERYGRHILLRDIGGQGQQKLKAARVLVIGAGGLGSPLIQYLAAAGLGEIGVVDDDAVSLSNLQRQILHGT
PDLGRPKVESAQEAVRRLNPHVVLTPFPTRLNGTNARGLIEAYDIVADGSDNFATRYLASDLCFHAKRPLVTGAVGAFDG
SLTTLRPFETGPDGHPNPTYRCLFPEPPPDGTVPTCEEAGVLGALTGMLGAMMALEVIREIVGFGEGLVGRLLLVDALHL
RFETLNYRWDPSNPLNGEPRAA

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=240, Percent_Identity=47.5, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI23510338, Length=184, Percent_Identity=29.3478260869565, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI23510340, Length=184, Percent_Identity=29.3478260869565, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4885649, Length=154, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI38045948, Length=178, Percent_Identity=33.7078651685393, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI38045942, Length=184, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI38045944, Length=187, Percent_Identity=30.4812834224599, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1787048, Length=260, Percent_Identity=41.1538461538462, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI87082356, Length=260, Percent_Identity=39.6153846153846, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789177, Length=162, Percent_Identity=31.4814814814815, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17540406, Length=258, Percent_Identity=39.922480620155, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI193203301, Length=177, Percent_Identity=29.9435028248588, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321903, Length=220, Percent_Identity=43.6363636363636, Blast_Score=193, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6320598, Length=177, Percent_Identity=31.638418079096, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582879, Length=232, Percent_Identity=48.7068965517241, Blast_Score=209, Evalue=1e-54,
Organism=Drosophila melanogaster, GI28573937, Length=194, Percent_Identity=30.4123711340206, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24660640, Length=141, Percent_Identity=29.0780141843972, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI20129973, Length=182, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 27974; Mature: 27974

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAVLSPEEIERYGRHILLRDIGGQGQQKLKAARVLVIGAGGLGSPLIQYLAAAGLGEIG
CEEECCHHHHHHHCCEEEEECCCCCCHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCCCC
VVDDDAVSLSNLQRQILHGTPDLGRPKVESAQEAVRRLNPHVVLTPFPTRLNGTNARGLI
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHH
EAYDIVADGSDNFATRYLASDLCFHAKRPLVTGAVGAFDGSLTTLRPFETGPDGHPNPTY
HHHHEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEECCCCCCCCCCCCCCE
RCLFPEPPPDGTVPTCEEAGVLGALTGMLGAMMALEVIREIVGFGEGLVGRLLLVDALHL
EEECCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RFETLNYRWDPSNPLNGEPRAA
HHHCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure
MVAVLSPEEIERYGRHILLRDIGGQGQQKLKAARVLVIGAGGLGSPLIQYLAAAGLGEIG
CEEECCHHHHHHHCCEEEEECCCCCCHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCCCC
VVDDDAVSLSNLQRQILHGTPDLGRPKVESAQEAVRRLNPHVVLTPFPTRLNGTNARGLI
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHH
EAYDIVADGSDNFATRYLASDLCFHAKRPLVTGAVGAFDGSLTTLRPFETGPDGHPNPTY
HHHHEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEECCCCCCCCCCCCCCE
RCLFPEPPPDGTVPTCEEAGVLGALTGMLGAMMALEVIREIVGFGEGLVGRLLLVDALHL
EEECCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RFETLNYRWDPSNPLNGEPRAA
HHHCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]