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The map label for this gene is rho [H]

Identifier: 182680467

GI number: 182680467

Start: 4046230

End: 4047498

Strand: Reverse

Name: rho [H]

Synonym: Bind_3567

Alternate gene names: 182680467

Gene position: 4047498-4046230 (Counterclockwise)

Preceding gene: 182680468

Following gene: 182680465

Centisome position: 97.06

GC content: 54.85

Gene sequence:

>1269_bases
ATGCGGGAAATCAAGCTGCAAGACTTGAAACTCAAGTCGCCGACCGAATTATTGGCCTTTGCCGAGGAACACGAGGTGGA
AAACGCCTCGATCATGCGCAAACAGGAATTGATGTTTGCGATCCTCAAACAATTGGCGAGCCGTGAGGTCGAGATCATCG
GCGAGGGCGTCATCGAGGTCCTGCAGGACGGCTTTGGCTTTCTGCGTTCGCCGGAAGCCAATTATCTCGCGGGTCCCGAC
GATATTTATGTCTCTCCCTCGCAAATACGGCGCTTTGGCCTGCGCACCGGTGACACCGTCGAGGGGTTGATCCGCAGCCC
CAAGGAAGGCGAACGTTATTTTGCGCTGCTCAAGGTCAATACGATCAATTTCGAGGACCCGGAGAAAATCCGCCACAAGG
TCCATTTCGACAATCTGACGCCGCTCTATCCTGATGAAAGGCTGAAGCTCGAAATCGATGATCCGACCAAGAAGGATCTT
TCGGCGCGCGTCATCGATATTGTCGCGCCAATCGGCAAGGGCCAGCGCGCTTTGATCGTTGCCCCGCCACGCACCGGTAA
AACCGTGCTGTTGCAGAATATCGCGCAATCCGTGACCGCCAATCATCCCGAATGCTATCTGATCGTTCTGCTGATCGATG
AAAGGCCGGAAGAAGTCACCGATATGCAGCGTTCGGTGAAGGGCGAGGTCATTTCCTCCACCTTTGACGAGCCGGCGGTG
CGCCATGTTCAGGTCGCCGAAATGGTGATCGAAAAAGCCAAAAGATTGGTGGAGCATGGCCGCGACGTGGTGATCCTTCT
GGATTCCATCACGCGTTTGGGTCGCGCTTATAATACGGTCGTGCCGTCATCGGGCAAGGTTCTGACCGGCGGTGTTGACG
CCAATGCCTTGCAACGTCCGAAACGGTTTTTTGGTGCCGCCCGTAATATCGAGGAAGGCGGTTCGCTGACCATTATCGCG
ACGGCCCTGATCGATACGGGTTCGCGCATGGATGAAGTGATTTTCGAGGAATTCAAAGGAACCGGCAATTCGGAAATTAT
CCTCGACCGCAAGGTGGCCGACAAACGCGTGTTCCCGGCGATCGATATCACGCGCTCCGGCACCCGCAAGGAAGAGCTGC
TGGTGCCAACCGATGTTTTGAAGAAAATGTATGTATTGCGGCGTATCCTCAACCCAATGGGTACGGTCGATGGCATCGAG
TTCCTGCTCGGCAAATTGCGCGAGACCCCAAAGGGCAATGCTACTTTCTTCGAGGCCATGAATACATAA

Upstream 100 bases:

>100_bases
CGGCATAGGCTTCGCTCCCTGAGCGAACTCGACCCTTCCCCTTCTCTTCCCGGATTTTCCTCAACACAGGATCTCCCTTT
CTCCCAAGGACTTCATCCCG

Downstream 100 bases:

>100_bases
GCATGGATCTGGGCATGATCTCCAAAAGGCCGGGCCTTTTGGAGATCATCCTATTTCATTGCGAGCGGCGTGAGAAGGAA
ACCGCGTAAGAACTGTCGCG

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MREIKLQDLKLKSPTELLAFAEEHEVENASIMRKQELMFAILKQLASREVEIIGEGVIEVLQDGFGFLRSPEANYLAGPD
DIYVSPSQIRRFGLRTGDTVEGLIRSPKEGERYFALLKVNTINFEDPEKIRHKVHFDNLTPLYPDERLKLEIDDPTKKDL
SARVIDIVAPIGKGQRALIVAPPRTGKTVLLQNIAQSVTANHPECYLIVLLIDERPEEVTDMQRSVKGEVISSTFDEPAV
RHVQVAEMVIEKAKRLVEHGRDVVILLDSITRLGRAYNTVVPSSGKVLTGGVDANALQRPKRFFGAARNIEEGGSLTIIA
TALIDTGSRMDEVIFEEFKGTGNSEIILDRKVADKRVFPAIDITRSGTRKEELLVPTDVLKKMYVLRRILNPMGTVDGIE
FLLGKLRETPKGNATFFEAMNT

Sequences:

>Translated_422_residues
MREIKLQDLKLKSPTELLAFAEEHEVENASIMRKQELMFAILKQLASREVEIIGEGVIEVLQDGFGFLRSPEANYLAGPD
DIYVSPSQIRRFGLRTGDTVEGLIRSPKEGERYFALLKVNTINFEDPEKIRHKVHFDNLTPLYPDERLKLEIDDPTKKDL
SARVIDIVAPIGKGQRALIVAPPRTGKTVLLQNIAQSVTANHPECYLIVLLIDERPEEVTDMQRSVKGEVISSTFDEPAV
RHVQVAEMVIEKAKRLVEHGRDVVILLDSITRLGRAYNTVVPSSGKVLTGGVDANALQRPKRFFGAARNIEEGGSLTIIA
TALIDTGSRMDEVIFEEFKGTGNSEIILDRKVADKRVFPAIDITRSGTRKEELLVPTDVLKKMYVLRRILNPMGTVDGIE
FLLGKLRETPKGNATFFEAMNT
>Mature_422_residues
MREIKLQDLKLKSPTELLAFAEEHEVENASIMRKQELMFAILKQLASREVEIIGEGVIEVLQDGFGFLRSPEANYLAGPD
DIYVSPSQIRRFGLRTGDTVEGLIRSPKEGERYFALLKVNTINFEDPEKIRHKVHFDNLTPLYPDERLKLEIDDPTKKDL
SARVIDIVAPIGKGQRALIVAPPRTGKTVLLQNIAQSVTANHPECYLIVLLIDERPEEVTDMQRSVKGEVISSTFDEPAV
RHVQVAEMVIEKAKRLVEHGRDVVILLDSITRLGRAYNTVVPSSGKVLTGGVDANALQRPKRFFGAARNIEEGGSLTIIA
TALIDTGSRMDEVIFEEFKGTGNSEIILDRKVADKRVFPAIDITRSGTRKEELLVPTDVLKKMYVLRRILNPMGTVDGIE
FLLGKLRETPKGNATFFEAMNT

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=417, Percent_Identity=69.5443645083933, Blast_Score=601, Evalue=1e-173,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 47197; Mature: 47197

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIKLQDLKLKSPTELLAFAEEHEVENASIMRKQELMFAILKQLASREVEIIGEGVIEV
CCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LQDGFGFLRSPEANYLAGPDDIYVSPSQIRRFGLRTGDTVEGLIRSPKEGERYFALLKVN
HHHCHHHHCCCCCCCCCCCCCEEECHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEEEEE
TINFEDPEKIRHKVHFDNLTPLYPDERLKLEIDDPTKKDLSARVIDIVAPIGKGQRALIV
EECCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHECCCCCCCEEEEE
APPRTGKTVLLQNIAQSVTANHPECYLIVLLIDERPEEVTDMQRSVKGEVISSTFDEPAV
ECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHCCCCHHH
RHVQVAEMVIEKAKRLVEHGRDVVILLDSITRLGRAYNTVVPSSGKVLTGGVDANALQRP
HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHH
KRFFGAARNIEEGGSLTIIATALIDTGSRMDEVIFEEFKGTGNSEIILDRKVADKRVFPA
HHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
IDITRSGTRKEELLVPTDVLKKMYVLRRILNPMGTVDGIEFLLGKLRETPKGNATFFEAM
EECCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEC
NT
CC
>Mature Secondary Structure
MREIKLQDLKLKSPTELLAFAEEHEVENASIMRKQELMFAILKQLASREVEIIGEGVIEV
CCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LQDGFGFLRSPEANYLAGPDDIYVSPSQIRRFGLRTGDTVEGLIRSPKEGERYFALLKVN
HHHCHHHHCCCCCCCCCCCCCEEECHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEEEEE
TINFEDPEKIRHKVHFDNLTPLYPDERLKLEIDDPTKKDLSARVIDIVAPIGKGQRALIV
EECCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHECCCCCCCEEEEE
APPRTGKTVLLQNIAQSVTANHPECYLIVLLIDERPEEVTDMQRSVKGEVISSTFDEPAV
ECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHCCCCHHH
RHVQVAEMVIEKAKRLVEHGRDVVILLDSITRLGRAYNTVVPSSGKVLTGGVDANALQRP
HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHH
KRFFGAARNIEEGGSLTIIATALIDTGSRMDEVIFEEFKGTGNSEIILDRKVADKRVFPA
HHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
IDITRSGTRKEELLVPTDVLKKMYVLRRILNPMGTVDGIEFLLGKLRETPKGNATFFEAM
EECCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEC
NT
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8606169 [H]