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The map label for this gene is atoS [H]

Identifier: 182680430

GI number: 182680430

Start: 4009958

End: 4011454

Strand: Reverse

Name: atoS [H]

Synonym: Bind_3530

Alternate gene names: 182680430

Gene position: 4011454-4009958 (Counterclockwise)

Preceding gene: 182680433

Following gene: 182680428

Centisome position: 96.19

GC content: 61.12

Gene sequence:

>1497_bases
ATGGCTGAAAGCATGACATCCGTCAGTCCCGATCATATCGCGGAAGCCACGGCTCATGAACCGCGCGCGCACAAGGCTTT
GCGCATCGGGCTGACGACGCGCGGGTTGCTCTTGATCATGATCTTCGTCTTCATCGGCGAAACCTTGATCTTCTTGCCAG
CGCTTTCGACATGGCGCGATGGCTGGCTGCGCAATCGGCTGAGCGCCGCCTATACCGCCGCCTTGGTGCTTGATGCATCG
CCGCGCGCCATGACGCCGGCCAATCTTTCGCAGGAATTGCTGGACAGTGTCGGCGCCCGCATCATCGTCCTGAAATCACA
CGGGACCAAGCGCATGCTCGCTGCGGCGCAATTGCCTCTGGAGGTCGACGAGACCTATGACCTGCGCCATACGGATCTCC
TGACCTCCATCCGCGCGACGATGCGTGCCCTGCTTGCCCGCCCTGACCGTGTTCTGACGATCGTCGGCGACGCCCCGATG
GGCGGTGACGCGATCGAGGTCACCATGGACGAAGCAAAGATGAAACGGGTGTTCTCCGATTATTCCTTGCGTGTCCTGAC
GATCACCCTGACGCTCTGCATCCTCGTCGGCGGCATGGCGGCGATCGCGATCCAATCCTTCATTCTCAATCCCGTGCGCC
GCCTGACCGAGAGCCTTGTGGACTTCGCCCAGAACCCCGAGGACCGGTCCCGCATCATCCAGGCTTCCGGCCATAATCAC
GAGATCGGCCAAGCCGAGGTGGCGCTCGCCAATATGCAGGACCGGTTGGCGCGTGAGCTGAATCAGAAGAAACATCTGGC
GGCTTTGGGGCTCGCCGTGGCCAAGATCAATCACGATTTGCGCAATATGCTCTTTTCCGCGCAATTGCTGTCAGACCGTC
TGGGCGATGTCCCAGATCCCTTGGCGCAGCGTTTGGCGCCCAAGCTGGTCGCGACGCTCGACCGGGCGATTCGTTTTTGC
CAGACGACGCTTGCCTATGGCCGCGCCGTGGATGATCCGCCGCAGCCACAACTTGTGTCCCTGCATCAAATCGTCGCCGA
GGCGATCGAGACCGTCACGCTTTCGATGCCGTGCAAGGTCCGCTTCATCAATGGGGTGGAGCCAGATTTCGAGGTGGTCG
CCGATGGTGAACAGATTTTCAGGGTCTTGATGAATCTGGTCCGCAACGGCGCGGAAGCTTTAACGAGTGTCGAGGCGACG
CTCGGCCGTGATCCCTACATCATGGTCAAGGCGTGGCGCGAGGACAATCACGTGATGATCGATGTCGCCGATAACGGCCC
AGGTGTTCCGAACCGGGCGCGGGCGGATCTCTTCGTCGCCTTCTTCAATTCGACGCGAGCAGGCGGTTCGGGTCTTGGCC
TAGTGATTGCCGCCGATCTCGTGCGCGCGCATGGCGGCACGATCAGCCTTCTGCCCGATGCGATGACGGGAGGCATTGGC
GCGACCTTCCGGATCGCCCTGCCAGATCTGATGGAAACCACGACCGTTCGGATGTGA

Upstream 100 bases:

>100_bases
AGTCCTGATTCATCCTCTCGAGAGCAAGGCACATTTGCTTGAAAGCCCATCTTTCTTCCGTGCCTTTCAAGTCCTTGCTC
AGGGGTTTTTGGGTTCGTCC

Downstream 100 bases:

>100_bases
AGAGGCTTCGAAACAAAAGAAGCGTACGAACCGTTCAGCTCCCTATTGCCAGAAGCCGCGCGAGCCGTTAAATGGTCACA
AATCTTGAGACCTTCTCCCA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MAESMTSVSPDHIAEATAHEPRAHKALRIGLTTRGLLLIMIFVFIGETLIFLPALSTWRDGWLRNRLSAAYTAALVLDAS
PRAMTPANLSQELLDSVGARIIVLKSHGTKRMLAAAQLPLEVDETYDLRHTDLLTSIRATMRALLARPDRVLTIVGDAPM
GGDAIEVTMDEAKMKRVFSDYSLRVLTITLTLCILVGGMAAIAIQSFILNPVRRLTESLVDFAQNPEDRSRIIQASGHNH
EIGQAEVALANMQDRLARELNQKKHLAALGLAVAKINHDLRNMLFSAQLLSDRLGDVPDPLAQRLAPKLVATLDRAIRFC
QTTLAYGRAVDDPPQPQLVSLHQIVAEAIETVTLSMPCKVRFINGVEPDFEVVADGEQIFRVLMNLVRNGAEALTSVEAT
LGRDPYIMVKAWREDNHVMIDVADNGPGVPNRARADLFVAFFNSTRAGGSGLGLVIAADLVRAHGGTISLLPDAMTGGIG
ATFRIALPDLMETTTVRM

Sequences:

>Translated_498_residues
MAESMTSVSPDHIAEATAHEPRAHKALRIGLTTRGLLLIMIFVFIGETLIFLPALSTWRDGWLRNRLSAAYTAALVLDAS
PRAMTPANLSQELLDSVGARIIVLKSHGTKRMLAAAQLPLEVDETYDLRHTDLLTSIRATMRALLARPDRVLTIVGDAPM
GGDAIEVTMDEAKMKRVFSDYSLRVLTITLTLCILVGGMAAIAIQSFILNPVRRLTESLVDFAQNPEDRSRIIQASGHNH
EIGQAEVALANMQDRLARELNQKKHLAALGLAVAKINHDLRNMLFSAQLLSDRLGDVPDPLAQRLAPKLVATLDRAIRFC
QTTLAYGRAVDDPPQPQLVSLHQIVAEAIETVTLSMPCKVRFINGVEPDFEVVADGEQIFRVLMNLVRNGAEALTSVEAT
LGRDPYIMVKAWREDNHVMIDVADNGPGVPNRARADLFVAFFNSTRAGGSGLGLVIAADLVRAHGGTISLLPDAMTGGIG
ATFRIALPDLMETTTVRM
>Mature_497_residues
AESMTSVSPDHIAEATAHEPRAHKALRIGLTTRGLLLIMIFVFIGETLIFLPALSTWRDGWLRNRLSAAYTAALVLDASP
RAMTPANLSQELLDSVGARIIVLKSHGTKRMLAAAQLPLEVDETYDLRHTDLLTSIRATMRALLARPDRVLTIVGDAPMG
GDAIEVTMDEAKMKRVFSDYSLRVLTITLTLCILVGGMAAIAIQSFILNPVRRLTESLVDFAQNPEDRSRIIQASGHNHE
IGQAEVALANMQDRLARELNQKKHLAALGLAVAKINHDLRNMLFSAQLLSDRLGDVPDPLAQRLAPKLVATLDRAIRFCQ
TTLAYGRAVDDPPQPQLVSLHQIVAEAIETVTLSMPCKVRFINGVEPDFEVVADGEQIFRVLMNLVRNGAEALTSVEATL
GRDPYIMVKAWREDNHVMIDVADNGPGVPNRARADLFVAFFNSTRAGGSGLGLVIAADLVRAHGGTISLLPDAMTGGIGA
TFRIALPDLMETTTVRM

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=29.8319327731092, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790300, Length=268, Percent_Identity=31.3432835820896, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=30.1255230125523, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=29.3172690763052, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54204; Mature: 54072

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESMTSVSPDHIAEATAHEPRAHKALRIGLTTRGLLLIMIFVFIGETLIFLPALSTWRD
CCCCCCCCCHHHHHHHCCCCCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH
GWLRNRLSAAYTAALVLDASPRAMTPANLSQELLDSVGARIIVLKSHGTKRMLAAAQLPL
HHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCC
EVDETYDLRHTDLLTSIRATMRALLARPDRVLTIVGDAPMGGDAIEVTMDEAKMKRVFSD
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEHHHHHHHHHHHC
YSLRVLTITLTLCILVGGMAAIAIQSFILNPVRRLTESLVDFAQNPEDRSRIIQASGHNH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCC
EIGQAEVALANMQDRLARELNQKKHLAALGLAVAKINHDLRNMLFSAQLLSDRLGDVPDP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LAQRLAPKLVATLDRAIRFCQTTLAYGRAVDDPPQPQLVSLHQIVAEAIETVTLSMPCKV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCEEE
RFINGVEPDFEVVADGEQIFRVLMNLVRNGAEALTSVEATLGRDPYIMVKAWREDNHVMI
EEECCCCCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEE
DVADNGPGVPNRARADLFVAFFNSTRAGGSGLGLVIAADLVRAHGGTISLLPDAMTGGIG
EECCCCCCCCCCCCHHEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHCCCCC
ATFRIALPDLMETTTVRM
CEEEEECHHHHHHHHCCC
>Mature Secondary Structure 
AESMTSVSPDHIAEATAHEPRAHKALRIGLTTRGLLLIMIFVFIGETLIFLPALSTWRD
CCCCCCCCHHHHHHHCCCCCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH
GWLRNRLSAAYTAALVLDASPRAMTPANLSQELLDSVGARIIVLKSHGTKRMLAAAQLPL
HHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCC
EVDETYDLRHTDLLTSIRATMRALLARPDRVLTIVGDAPMGGDAIEVTMDEAKMKRVFSD
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEHHHHHHHHHHHC
YSLRVLTITLTLCILVGGMAAIAIQSFILNPVRRLTESLVDFAQNPEDRSRIIQASGHNH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCC
EIGQAEVALANMQDRLARELNQKKHLAALGLAVAKINHDLRNMLFSAQLLSDRLGDVPDP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LAQRLAPKLVATLDRAIRFCQTTLAYGRAVDDPPQPQLVSLHQIVAEAIETVTLSMPCKV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCEEE
RFINGVEPDFEVVADGEQIFRVLMNLVRNGAEALTSVEATLGRDPYIMVKAWREDNHVMI
EEECCCCCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEE
DVADNGPGVPNRARADLFVAFFNSTRAGGSGLGLVIAADLVRAHGGTISLLPDAMTGGIG
EECCCCCCCCCCCCHHEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHCCCCC
ATFRIALPDLMETTTVRM
CEEEEECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]