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The map label for this gene is rfbC [C]

Identifier: 182680403

GI number: 182680403

Start: 3980503

End: 3981078

Strand: Reverse

Name: rfbC [C]

Synonym: Bind_3503

Alternate gene names: 182680403

Gene position: 3981078-3980503 (Counterclockwise)

Preceding gene: 182680405

Following gene: 182680402

Centisome position: 95.47

GC content: 58.68

Gene sequence:

>576_bases
ATGGCCTTGACCGTCGAAAAACTCGCAATTCCGGATGTCTTGCTGATTCGCCCCAAAAAATTCGGGGATGCGCGCGGCTA
TTTTGCCGAAACTTATAATGCCCGCGCCTATTGCGAAGCCGGAATCGATTGCGTCTTTGTGCAAGACAATCAATCGCTGT
CCGTGGAGAAGGGCACGATCCGTGGCCTGCACTTCCAGGTGCCGCCAGAGCCGCAGGCCAAATTGGTCCGCGTCTTGCGC
GGCGCCATTCTCGATGTCGCGGTCGATCTGCGGCGCGGGAGCCCGCATTACGGTCAATGGTGCGGTGCGACTTTGACCGC
CGAGGAAGGAGAACAGCTCTTCGTCCCACGCGGCTTCGCGCATGGCTTCTGCACGCTCATGCCCGAGACCGAAGTTGCCT
ATAAGGTCGATGGTTTCTATGCGCCCGGCTGCGACGCGGGCCTGCGTTATGATGATCCCGATATCAATATCCCCTGGCCG
CTCGATGGGAAAGCGGCGATGATCTCGGATAAGGACGGCAAGCTCCCCTTCCTGCGTGATTTCAAGTCTCCCTTCACTTT
CGAGGTGCCGGCATGA

Upstream 100 bases:

>100_bases
ATTTGAGCAAGAGCCATGCTGGAGAGAACGGGCACGGTGGACTCCTGATGCAAGGCAAGGCAAAAGGAGGCCGGAGCCGA
TTCAAGGAGCGCCGCCCTTC

Downstream 100 bases:

>100_bases
TGGCGCGTTTTCTCGTGACCGGCGGTGCCGGCTTCATTGGCTCGGCCGTGGTCCGTCACCTGATCGAGGATACGCCGCAC
GAGGTTTGCGTCCTCGACAA

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MALTVEKLAIPDVLLIRPKKFGDARGYFAETYNARAYCEAGIDCVFVQDNQSLSVEKGTIRGLHFQVPPEPQAKLVRVLR
GAILDVAVDLRRGSPHYGQWCGATLTAEEGEQLFVPRGFAHGFCTLMPETEVAYKVDGFYAPGCDAGLRYDDPDINIPWP
LDGKAAMISDKDGKLPFLRDFKSPFTFEVPA

Sequences:

>Translated_191_residues
MALTVEKLAIPDVLLIRPKKFGDARGYFAETYNARAYCEAGIDCVFVQDNQSLSVEKGTIRGLHFQVPPEPQAKLVRVLR
GAILDVAVDLRRGSPHYGQWCGATLTAEEGEQLFVPRGFAHGFCTLMPETEVAYKVDGFYAPGCDAGLRYDDPDINIPWP
LDGKAAMISDKDGKLPFLRDFKSPFTFEVPA
>Mature_190_residues
ALTVEKLAIPDVLLIRPKKFGDARGYFAETYNARAYCEAGIDCVFVQDNQSLSVEKGTIRGLHFQVPPEPQAKLVRVLRG
AILDVAVDLRRGSPHYGQWCGATLTAEEGEQLFVPRGFAHGFCTLMPETEVAYKVDGFYAPGCDAGLRYDDPDINIPWPL
DGKAAMISDKDGKLPFLRDFKSPFTFEVPA

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=174, Percent_Identity=43.1034482758621, Blast_Score=144, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17550412, Length=167, Percent_Identity=42.5149700598802, Blast_Score=130, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21115; Mature: 20984

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTVEKLAIPDVLLIRPKKFGDARGYFAETYNARAYCEAGIDCVFVQDNQSLSVEKGTI
CCEECCHHCCCCEEEECCCCCCCCCCCEEECCCCEEEEECCCEEEEEECCCCEEEECCEE
RGLHFQVPPEPQAKLVRVLRGAILDVAVDLRRGSPHYGQWCGATLTAEEGEQLFVPRGFA
EEEEEECCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEECCCCCEEEEECCCC
HGFCTLMPETEVAYKVDGFYAPGCDAGLRYDDPDINIPWPLDGKAAMISDKDGKLPFLRD
CCEEEECCCCCEEEEECCEECCCCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCHHHH
FKSPFTFEVPA
CCCCEEEECCC
>Mature Secondary Structure 
ALTVEKLAIPDVLLIRPKKFGDARGYFAETYNARAYCEAGIDCVFVQDNQSLSVEKGTI
CEECCHHCCCCEEEECCCCCCCCCCCEEECCCCEEEEECCCEEEEEECCCCEEEECCEE
RGLHFQVPPEPQAKLVRVLRGAILDVAVDLRRGSPHYGQWCGATLTAEEGEQLFVPRGFA
EEEEEECCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCEEECCCCCEEEEECCCC
HGFCTLMPETEVAYKVDGFYAPGCDAGLRYDDPDINIPWPLDGKAAMISDKDGKLPFLRD
CCEEEECCCCCEEEEECCEECCCCCCCCEECCCCCCCCCCCCCCEEEEECCCCCCCHHHH
FKSPFTFEVPA
CCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]