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The map label for this gene is marC [H]

Identifier: 182680248

GI number: 182680248

Start: 3802609

End: 3803262

Strand: Reverse

Name: marC [H]

Synonym: Bind_3347

Alternate gene names: 182680248

Gene position: 3803262-3802609 (Counterclockwise)

Preceding gene: 182680255

Following gene: 182680247

Centisome position: 91.2

GC content: 57.03

Gene sequence:

>654_bases
ATGGACCTGTTCTTTCTCTCCGTAAGATATGTGTTCGTCGTTGCCATCGGCCTCTTGCCGATCATGAATCCGCTCAGCAC
CATTCCACTCTTTCTCGCCTTGACCCGACGGATGGAGCCGGAGCGCCAGCGGCGGCAGGCTGCCCGTGCATCAATCTATG
CCTTTGCAATTCTTGCGGCTTTTCTGCTCGTCGGCAATGGGATCATCGCGCTCTTCGGCATTTCCATGCCGGGCATCCGC
GTGGCTGGCGGCCTGATCATCCTCGTCCTTGCCTTTCGCATGCTCTTCGCCGGAGAAACGCCCGCAAAGACGCAGGGCGA
TGAGGAAGGCTTCGAACAGCACGAGGCTGATTATTCGTTTTCACCTCTTGCCATGCCGAGCCTCGCCGGTCCCGGCTCGA
TCGCCGTGGTGATGAGCTATGGATCGGAAATCCCAGAAAAATATGAGGTTCTTGGCCATTTCGTCGTGCTGTGCGGGATC
GGTATTGTGGTGGCCTGCGCCTATGTGGCACTTGCTGGTGCTGTGAGGATCGCCAAATTCCTTGGCGAGGCGGGCATCCA
GTCCGTCACCAAGATCATGGGTTTTCTCCTAGCCTGCGTCGCCGTCCAATTCATCGCCTCCGGCATCAGAGATTTCATCA
TCTCTTTCAGTTGA

Upstream 100 bases:

>100_bases
TGCCAGATACGCGGGCTTGGCGGACAAAGGAGGGCGCTTTGACCCGTGGGTTCTCGCGCCGCCGATTTCCTTGTGTCATG
CCAGCTTGGCCGAGACCTTC

Downstream 100 bases:

>100_bases
ATGGGAGTGAGGGCAAATCCTTGCCCTTACAACCTTGGCCTTGCCTTCCTATCTTCATAGATTGCCGCGACCTTTTGGAG
GTGACGAGCCCCCTCTTTCA

Product: multiple drug resistance protein MarC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MDLFFLSVRYVFVVAIGLLPIMNPLSTIPLFLALTRRMEPERQRRQAARASIYAFAILAAFLLVGNGIIALFGISMPGIR
VAGGLIILVLAFRMLFAGETPAKTQGDEEGFEQHEADYSFSPLAMPSLAGPGSIAVVMSYGSEIPEKYEVLGHFVVLCGI
GIVVACAYVALAGAVRIAKFLGEAGIQSVTKIMGFLLACVAVQFIASGIRDFIISFS

Sequences:

>Translated_217_residues
MDLFFLSVRYVFVVAIGLLPIMNPLSTIPLFLALTRRMEPERQRRQAARASIYAFAILAAFLLVGNGIIALFGISMPGIR
VAGGLIILVLAFRMLFAGETPAKTQGDEEGFEQHEADYSFSPLAMPSLAGPGSIAVVMSYGSEIPEKYEVLGHFVVLCGI
GIVVACAYVALAGAVRIAKFLGEAGIQSVTKIMGFLLACVAVQFIASGIRDFIISFS
>Mature_217_residues
MDLFFLSVRYVFVVAIGLLPIMNPLSTIPLFLALTRRMEPERQRRQAARASIYAFAILAAFLLVGNGIIALFGISMPGIR
VAGGLIILVLAFRMLFAGETPAKTQGDEEGFEQHEADYSFSPLAMPSLAGPGSIAVVMSYGSEIPEKYEVLGHFVVLCGI
GIVVACAYVALAGAVRIAKFLGEAGIQSVTKIMGFLLACVAVQFIASGIRDFIISFS

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=202, Percent_Identity=38.1188118811881, Blast_Score=140, Evalue=4e-35,
Organism=Escherichia coli, GI1787494, Length=196, Percent_Identity=30.1020408163265, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789842, Length=199, Percent_Identity=27.6381909547739, Blast_Score=94, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 23214; Mature: 23214

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFFLSVRYVFVVAIGLLPIMNPLSTIPLFLALTRRMEPERQRRQAARASIYAFAILAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
FLLVGNGIIALFGISMPGIRVAGGLIILVLAFRMLFAGETPAKTQGDEEGFEQHEADYSF
HHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCC
SPLAMPSLAGPGSIAVVMSYGSEIPEKYEVLGHFVVLCGIGIVVACAYVALAGAVRIAKF
CCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEAGIQSVTKIMGFLLACVAVQFIASGIRDFIISFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLFFLSVRYVFVVAIGLLPIMNPLSTIPLFLALTRRMEPERQRRQAARASIYAFAILAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
FLLVGNGIIALFGISMPGIRVAGGLIILVLAFRMLFAGETPAKTQGDEEGFEQHEADYSF
HHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCC
SPLAMPSLAGPGSIAVVMSYGSEIPEKYEVLGHFVVLCGIGIVVACAYVALAGAVRIAKF
CCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEAGIQSVTKIMGFLLACVAVQFIASGIRDFIISFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA