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The map label for this gene is 182680247

Identifier: 182680247

GI number: 182680247

Start: 3801492

End: 3802481

Strand: Reverse

Name: 182680247

Synonym: Bind_3346

Alternate gene names: NA

Gene position: 3802481-3801492 (Counterclockwise)

Preceding gene: 182680248

Following gene: 182680243

Centisome position: 91.18

GC content: 59.19

Gene sequence:

>990_bases
ATGCCCCGTAACCCCTATTATGCCGGCCCTCTGTCGGATCATTTCGATGGCACGCGTTTTTTTGTGCCGGGCGAAAGGCC
GAAGACGAATCGTTTCTCCGATTTCCTCAAATGGAGATTCGCCAGCCGGCACGGTCCCAAATGGCCGGTGACCTTTCCAA
GCCCGGCGCGTGATAAGCCGCCGGCGCGGGTCGAAGGCGCGGATCTGCGTGTATCCTTTATCGGCCATGCGAGTTTTCTA
CTTCAGACCCAGGGGCTCAACCTTCTTCTGGATCCGGTCTTTTCAGAACGCGTGAGCCCGTTCCGGTCCGTCGGACCGAA
ACGTGTCAATCCGCCGGGTATCGCTCTTGAGGATCTGCCGGAGATCGATGCGATTCTCGTCACCCATAATCATTATGATC
ATCTCGATCTGCCGACGCTGTCGCAACTCGCCGGCTGTCGGGTCCTGTCGCCGCTCGGCAATGAAACGATCATGCGCACT
CATGATGCACGCATCAGAGCCGAGGCCCATGATTGGGGCGCGCGGATTTCGATTGGCAATGAGGTCTTCATTCATTTCGA
GCCCTGCTATCATTGGTCAGCGCGTGGCCTGTCCGATCGCCGCATGGCTCTCTGGGCGGCTTTCGTCATCGAGACGCCGG
CCGGCAAAATCTACCATATCGGCGATACAGCCTATGGCAGGGGAGAGATTTTCCGGGCGATGCGGGTGAAGCATGGGCCT
TTCCGGCTGGCCCTGGTTCCGATCGGTGCTTATGAGCCGCGCTGGTTCATGCGCGAACATCATGTTGATCCAGAGGAGGC
CGTCCGCATCTTTCAGGATTGCGGCGCGGCTTACGGTCTCGCGCATCATTGGGGCACGTTCCACCTGACCGATGAGGCGA
TCGATGAGCCACCCAAAAGGCTCGCTGTCGCGCTCGAACGAGCAGGCGTTGCGCCGGGGCATTTTCAGGTGAAGCGTCCG
GGCGAGGTTTTCAAAGTGCCCCTGGAATGA

Upstream 100 bases:

>100_bases
TACAACCTTGGCCTTGCCTTCCTATCTTCATAGATTGCCGCGACCTTTTGGAGGTGACGAGCCCCCTCTTTCAGCCGCCT
GGATGTCAAACGGATAAGGC

Downstream 100 bases:

>100_bases
GGACGGGCGTGGCTAACCGGGCTAGATCGATGATGGCTTTGCGTGTTCCTGAATGAAATGGAGAAGGGACAGCAGCGGGG
CAGGGCAATTGGACAGGACG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPRNPYYAGPLSDHFDGTRFFVPGERPKTNRFSDFLKWRFASRHGPKWPVTFPSPARDKPPARVEGADLRVSFIGHASFL
LQTQGLNLLLDPVFSERVSPFRSVGPKRVNPPGIALEDLPEIDAILVTHNHYDHLDLPTLSQLAGCRVLSPLGNETIMRT
HDARIRAEAHDWGARISIGNEVFIHFEPCYHWSARGLSDRRMALWAAFVIETPAGKIYHIGDTAYGRGEIFRAMRVKHGP
FRLALVPIGAYEPRWFMREHHVDPEEAVRIFQDCGAAYGLAHHWGTFHLTDEAIDEPPKRLAVALERAGVAPGHFQVKRP
GEVFKVPLE

Sequences:

>Translated_329_residues
MPRNPYYAGPLSDHFDGTRFFVPGERPKTNRFSDFLKWRFASRHGPKWPVTFPSPARDKPPARVEGADLRVSFIGHASFL
LQTQGLNLLLDPVFSERVSPFRSVGPKRVNPPGIALEDLPEIDAILVTHNHYDHLDLPTLSQLAGCRVLSPLGNETIMRT
HDARIRAEAHDWGARISIGNEVFIHFEPCYHWSARGLSDRRMALWAAFVIETPAGKIYHIGDTAYGRGEIFRAMRVKHGP
FRLALVPIGAYEPRWFMREHHVDPEEAVRIFQDCGAAYGLAHHWGTFHLTDEAIDEPPKRLAVALERAGVAPGHFQVKRP
GEVFKVPLE
>Mature_328_residues
PRNPYYAGPLSDHFDGTRFFVPGERPKTNRFSDFLKWRFASRHGPKWPVTFPSPARDKPPARVEGADLRVSFIGHASFLL
QTQGLNLLLDPVFSERVSPFRSVGPKRVNPPGIALEDLPEIDAILVTHNHYDHLDLPTLSQLAGCRVLSPLGNETIMRTH
DARIRAEAHDWGARISIGNEVFIHFEPCYHWSARGLSDRRMALWAAFVIETPAGKIYHIGDTAYGRGEIFRAMRVKHGPF
RLALVPIGAYEPRWFMREHHVDPEEAVRIFQDCGAAYGLAHHWGTFHLTDEAIDEPPKRLAVALERAGVAPGHFQVKRPG
EVFKVPLE

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=280, Percent_Identity=40, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI170932481, Length=280, Percent_Identity=40, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17543100, Length=253, Percent_Identity=35.1778656126482, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17543102, Length=253, Percent_Identity=35.1778656126482, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI25148824, Length=253, Percent_Identity=35.1778656126482, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17543104, Length=270, Percent_Identity=34.0740740740741, Blast_Score=158, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6325154, Length=245, Percent_Identity=32.6530612244898, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37193; Mature: 37062

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRNPYYAGPLSDHFDGTRFFVPGERPKTNRFSDFLKWRFASRHGPKWPVTFPSPARDKP
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCC
PARVEGADLRVSFIGHASFLLQTQGLNLLLDPVFSERVSPFRSVGPKRVNPPGIALEDLP
CCCCCCCEEEEEEECCEEEEEEECCCCEEECHHHHHHCCHHHHCCCCCCCCCCCCHHCCC
EIDAILVTHNHYDHLDLPTLSQLAGCRVLSPLGNETIMRTHDARIRAEAHDWGARISIGN
CCEEEEEECCCCCCCCCCCHHHHHCCEEECCCCCCCEEEECCCEEEEECCCCCCEEEECC
EVFIHFEPCYHWSARGLSDRRMALWAAFVIETPAGKIYHIGDTAYGRGEIFRAMRVKHGP
EEEEEEECCCCCCCCCCCCHHHEEEEEEEEECCCCCEEECCCCCCCHHHHHHHHHCCCCC
FRLALVPIGAYEPRWFMREHHVDPEEAVRIFQDCGAAYGLAHHWGTFHLTDEAIDEPPKR
EEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCEEEECHHHHCCCHHH
LAVALERAGVAPGHFQVKRPGEVFKVPLE
HHHHHHHCCCCCCCEEEECCCCEEEECCC
>Mature Secondary Structure 
PRNPYYAGPLSDHFDGTRFFVPGERPKTNRFSDFLKWRFASRHGPKWPVTFPSPARDKP
CCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCC
PARVEGADLRVSFIGHASFLLQTQGLNLLLDPVFSERVSPFRSVGPKRVNPPGIALEDLP
CCCCCCCEEEEEEECCEEEEEEECCCCEEECHHHHHHCCHHHHCCCCCCCCCCCCHHCCC
EIDAILVTHNHYDHLDLPTLSQLAGCRVLSPLGNETIMRTHDARIRAEAHDWGARISIGN
CCEEEEEECCCCCCCCCCCHHHHHCCEEECCCCCCCEEEECCCEEEEECCCCCCEEEECC
EVFIHFEPCYHWSARGLSDRRMALWAAFVIETPAGKIYHIGDTAYGRGEIFRAMRVKHGP
EEEEEEECCCCCCCCCCCCHHHEEEEEEEEECCCCCEEECCCCCCCHHHHHHHHHCCCCC
FRLALVPIGAYEPRWFMREHHVDPEEAVRIFQDCGAAYGLAHHWGTFHLTDEAIDEPPKR
EEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCEEEECHHHHCCCHHH
LAVALERAGVAPGHFQVKRPGEVFKVPLE
HHHHHHHCCCCCCCEEEECCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]