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The map label for this gene is glk [H]

Identifier: 182680195

GI number: 182680195

Start: 3745371

End: 3746333

Strand: Reverse

Name: glk [H]

Synonym: Bind_3293

Alternate gene names: 182680195

Gene position: 3746333-3745371 (Counterclockwise)

Preceding gene: 182680196

Following gene: 182680194

Centisome position: 89.84

GC content: 60.44

Gene sequence:

>963_bases
TTGGAGATCGTGGCGGTCGATATCGGGGGGACGCATGCCCGTTTCGCCTTGGCCGAAGTGGCTGATGGCCGGGTGGTGCA
TCTCGGTGAGGCTGTCACGTTGCAAGCTGCGGAGCATGGGAGTTTCCAGCTCGCCTGGGAGACTTTCGCGCAAATCGCTG
GCCGCGCCTTGCCGCGCGCCGTGGCCATTGCCATAGCCTGTCCCGTCGGCGGCGAAGTTCTGAAACTCACCAATAATCCC
TGGATTATCCGTCCGGCTTTGATCCCCGAAAAGCTTCATGTCGATGCCTGGACGCTCGTCAATGATTTCGGGGCGATTGC
CCATACTGTCGCGCAAGTCGGTGAAGATCAGCTCATGCCGATTACCGGCCCTGATCACGCTTTGCCGCAAGACGGTGTCA
TCAGTATCGTCGGCCCCGGGACGGGGCTTGGCGTGGGACACGTGCTGCGCCGCGGCGGACATTATCATGTCATTGAATGC
GAGGGTGGCCATATTGATTTCGCACCCCTCGATAGCCTGGAAGATCAGATCCTCAAATATATGCGGCATCGCTACCCCCG
TGTTTCGGTCGAGCGACTGATTTCGGGACCTGGGCTCGTCAATATTTATGAAGCGCTGGCCGCGATCGAAGGAAAATCGC
TCGACCCGATCGGCGACAAGGAATTATGGGCAGCGGCCATGGCGGGCAAGGATAGTCTTGCAGCGGCGGCGCTCGACCGC
TTTTGTCTGAGCCTTGGTGCGGTCTGTGGTGATATCGCTTTGGCTTTGGGGGCTAAATCGGTGGTCATCGCCGGCGGGCT
CGGCCTGCGCATTGCCTCCTTGCTCCCGCAATCGGGCTTTGCCACGCGCTTCACCGCCAAGGGGCGGTTTGCGCCAATGA
TGGCGACGATTCCCGTGCGGTGCATCATCCATCCGCAGCCAGGACTTTATGGAGCCGCGGCCGCCTTCGCCGTGGAACAT
TGA

Upstream 100 bases:

>100_bases
TGACAAGCTTTTTTTGTCCTGTATTTTTGCATAATACCTATACATAAATAGCTGAGCTCCTCCTCACGAAGCGAGAGAGA
GCCAAGTGGGGAGGCGGGAT

Downstream 100 bases:

>100_bases
TGGCGCATATCCTGAGCCTGTCTGTTTGAAGTGAAAGCCGGAGAGAAGCTCTGGCTTTGGAAAAAGGCATCACCTGAATC
CAAAGGCGGTATCACTTCTG

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MEIVAVDIGGTHARFALAEVADGRVVHLGEAVTLQAAEHGSFQLAWETFAQIAGRALPRAVAIAIACPVGGEVLKLTNNP
WIIRPALIPEKLHVDAWTLVNDFGAIAHTVAQVGEDQLMPITGPDHALPQDGVISIVGPGTGLGVGHVLRRGGHYHVIEC
EGGHIDFAPLDSLEDQILKYMRHRYPRVSVERLISGPGLVNIYEALAAIEGKSLDPIGDKELWAAAMAGKDSLAAAALDR
FCLSLGAVCGDIALALGAKSVVIAGGLGLRIASLLPQSGFATRFTAKGRFAPMMATIPVRCIIHPQPGLYGAAAAFAVEH

Sequences:

>Translated_320_residues
MEIVAVDIGGTHARFALAEVADGRVVHLGEAVTLQAAEHGSFQLAWETFAQIAGRALPRAVAIAIACPVGGEVLKLTNNP
WIIRPALIPEKLHVDAWTLVNDFGAIAHTVAQVGEDQLMPITGPDHALPQDGVISIVGPGTGLGVGHVLRRGGHYHVIEC
EGGHIDFAPLDSLEDQILKYMRHRYPRVSVERLISGPGLVNIYEALAAIEGKSLDPIGDKELWAAAMAGKDSLAAAALDR
FCLSLGAVCGDIALALGAKSVVIAGGLGLRIASLLPQSGFATRFTAKGRFAPMMATIPVRCIIHPQPGLYGAAAAFAVEH
>Mature_320_residues
MEIVAVDIGGTHARFALAEVADGRVVHLGEAVTLQAAEHGSFQLAWETFAQIAGRALPRAVAIAIACPVGGEVLKLTNNP
WIIRPALIPEKLHVDAWTLVNDFGAIAHTVAQVGEDQLMPITGPDHALPQDGVISIVGPGTGLGVGHVLRRGGHYHVIEC
EGGHIDFAPLDSLEDQILKYMRHRYPRVSVERLISGPGLVNIYEALAAIEGKSLDPIGDKELWAAAMAGKDSLAAAALDR
FCLSLGAVCGDIALALGAKSVVIAGGLGLRIASLLPQSGFATRFTAKGRFAPMMATIPVRCIIHPQPGLYGAAAAFAVEH

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=310, Percent_Identity=33.5483870967742, Blast_Score=168, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33558; Mature: 33558

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIVAVDIGGTHARFALAEVADGRVVHLGEAVTLQAAEHGSFQLAWETFAQIAGRALPRA
CEEEEEECCCCCHHEEHHHHCCCCEEEECCEEEEEECCCCCEEEHHHHHHHHHHHHCCCE
VAIAIACPVGGEVLKLTNNPWIIRPALIPEKLHVDAWTLVNDFGAIAHTVAQVGEDQLMP
EEEEEECCCCCEEEEECCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCEEE
ITGPDHALPQDGVISIVGPGTGLGVGHVLRRGGHYHVIECEGGHIDFAPLDSLEDQILKY
ECCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCEEEEEECCCEEECCCCCHHHHHHHHH
MRHRYPRVSVERLISGPGLVNIYEALAAIEGKSLDPIGDKELWAAAMAGKDSLAAAALDR
HHHCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
FCLSLGAVCGDIALALGAKSVVIAGGLGLRIASLLPQSGFATRFTAKGRFAPMMATIPVR
HHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCCCCEEEECCCCCCCEEEECCEE
CIIHPQPGLYGAAAAFAVEH
EEEECCCCCCHHHHHHEECC
>Mature Secondary Structure
MEIVAVDIGGTHARFALAEVADGRVVHLGEAVTLQAAEHGSFQLAWETFAQIAGRALPRA
CEEEEEECCCCCHHEEHHHHCCCCEEEECCEEEEEECCCCCEEEHHHHHHHHHHHHCCCE
VAIAIACPVGGEVLKLTNNPWIIRPALIPEKLHVDAWTLVNDFGAIAHTVAQVGEDQLMP
EEEEEECCCCCEEEEECCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCEEE
ITGPDHALPQDGVISIVGPGTGLGVGHVLRRGGHYHVIECEGGHIDFAPLDSLEDQILKY
ECCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCEEEEEECCCEEECCCCCHHHHHHHHH
MRHRYPRVSVERLISGPGLVNIYEALAAIEGKSLDPIGDKELWAAAMAGKDSLAAAALDR
HHHCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
FCLSLGAVCGDIALALGAKSVVIAGGLGLRIASLLPQSGFATRFTAKGRFAPMMATIPVR
HHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCCCCEEEECCCCCCCEEEECCEE
CIIHPQPGLYGAAAAFAVEH
EEEECCCCCCHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254282 [H]