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The map label for this gene is cdd [H]

Identifier: 182680003

GI number: 182680003

Start: 3545670

End: 3546086

Strand: Reverse

Name: cdd [H]

Synonym: Bind_3099

Alternate gene names: 182680003

Gene position: 3546086-3545670 (Counterclockwise)

Preceding gene: 182680005

Following gene: 182680001

Centisome position: 85.03

GC content: 59.95

Gene sequence:

>417_bases
ATGGATCCGCTGGAGGAACTCTGGAGCGCGGCTTTGGCGGTGTTCGACAGGGCTTATGCGCCTTATTCCCGCTTTAAAGT
GGCGGCGGCCGTGCGCAGCGTTTCAGGCGCCGTATTTGTCGGGGTGAATGTCGAAAATGCCGCTTATCCGGTCGGAACCT
GCGCGGAAGCCGGCGCTATCGCGGCCATGATCACGGCTGGAGAGCGGAGCATCGACGCCATTTTCATTCTTGGAGATGGC
GCAGGTCATACGACGCCTTGCGGCGCCTGTCGGCAACGCCTTCATGAGTTCTCGGCGCCGGAGACTTTGGTGCATGTCGG
AGGGCCAGAGGGGCATCGCGCTACATATACAATGGCCGAATTGTTACCACACGGATTTGCGCTCGATCGTCCTCGCGATG
CTGACGAACAGGACTGA

Upstream 100 bases:

>100_bases
GTGGCTTCTGGAATATTTGGGAGCTTAACCGATGAGGACTGGGAGGGTTCCCATCCATCCCTTTCGACTTGTCAGGCCAT
GCGAAGGAAAGGGGGAGGGA

Downstream 100 bases:

>100_bases
AAATACAAAAGCCCCGGCAATGAGCCAGGGCCATGAAGAGAGACCGGGTGAAACGGCTAGAGCATCAACCGGCACTCTTG
AGCCGGCGTCAGGGGCTCGC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MDPLEELWSAALAVFDRAYAPYSRFKVAAAVRSVSGAVFVGVNVENAAYPVGTCAEAGAIAAMITAGERSIDAIFILGDG
AGHTTPCGACRQRLHEFSAPETLVHVGGPEGHRATYTMAELLPHGFALDRPRDADEQD

Sequences:

>Translated_138_residues
MDPLEELWSAALAVFDRAYAPYSRFKVAAAVRSVSGAVFVGVNVENAAYPVGTCAEAGAIAAMITAGERSIDAIFILGDG
AGHTTPCGACRQRLHEFSAPETLVHVGGPEGHRATYTMAELLPHGFALDRPRDADEQD
>Mature_138_residues
MDPLEELWSAALAVFDRAYAPYSRFKVAAAVRSVSGAVFVGVNVENAAYPVGTCAEAGAIAAMITAGERSIDAIFILGDG
AGHTTPCGACRQRLHEFSAPETLVHVGGPEGHRATYTMAELLPHGFALDRPRDADEQD

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=124, Percent_Identity=38.7096774193548, Blast_Score=89, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17551074, Length=134, Percent_Identity=33.5820895522388, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540514, Length=121, Percent_Identity=38.8429752066116, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323274, Length=126, Percent_Identity=38.0952380952381, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19920920, Length=110, Percent_Identity=45.4545454545455, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24582744, Length=136, Percent_Identity=37.5, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582741, Length=134, Percent_Identity=35.8208955223881, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14559; Mature: 14559

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPLEELWSAALAVFDRAYAPYSRFKVAAAVRSVSGAVFVGVNVENAAYPVGTCAEAGAI
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCE
AAMITAGERSIDAIFILGDGAGHTTPCGACRQRLHEFSAPETLVHVGGPEGHRATYTMAE
EEEEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHH
LLPHGFALDRPRDADEQD
HCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDPLEELWSAALAVFDRAYAPYSRFKVAAAVRSVSGAVFVGVNVENAAYPVGTCAEAGAI
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCE
AAMITAGERSIDAIFILGDGAGHTTPCGACRQRLHEFSAPETLVHVGGPEGHRATYTMAE
EEEEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHH
LLPHGFALDRPRDADEQD
HCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7569993; 8253680 [H]