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The map label for this gene is acoR [H]

Identifier: 182680001

GI number: 182680001

Start: 3543036

End: 3544910

Strand: Reverse

Name: acoR [H]

Synonym: Bind_3097

Alternate gene names: 182680001

Gene position: 3544910-3543036 (Counterclockwise)

Preceding gene: 182680003

Following gene: 182680000

Centisome position: 85.01

GC content: 61.39

Gene sequence:

>1875_bases
ATGGGGTCCGGGGATGGGAGAATGCCGGTTGCCGCCACGGCGCATGCGGAACGGATCTTCACCGCCTCATTCGGTGGGGC
GGAAACGGGCGATGGACCCGTCGGCTCTTTGATCATTGCGTCCTGGCGCCGCTGCCTCGATCGCCATAAGCTCGATCCCG
AACGTCAGGCCGAGACGCGCGTCCTGTCTCGCGGCGAATTGCGCGAGGCGCGGGAACCGCTCGACGCCCTTTTATCCCTC
TCCACGCCGCTTCTCGATGATCTTTATCGGCAGGTCGCCGATCTAGGCTATGTCGTCATGCTCACCGATGGCAATGGCAT
AACCTTGAACGCGCGGGCGGGAAATGACGAGCGCGCCTTTCGGAAATGGGGGCTTTGGACCGGCTCCGTCTGGAGCGAGG
GGCTTGAAGGCACCAATGGCGTCGGCCTGTGCCTGACCGAGCAACGGCCGGTCACGGTGCATCGTGGCGAGCATTTCCGC
TCCCGCCACGCGGGCCTGACCTGCACCGTTGCGCCGCTCTTTAATGCCGATGGGACGATCATCGGCTGTCTTGATATATC
GGCCTTCAACCAGGAGATCGACAGCCGCATCGTCGGTTTCGCGCAACGCGCGACGACGCTTGCCGCCGGTTGGATCGAGG
CTGTCTGTTTCCGGCACGCCTATCGATCCTGCTGGATCGTCTCGCTTGGGGAGTCGATCGAGGGCAAGGCGCTGCTCGCC
TTCGACGAGGACCGGCGGCTCAAGGGCGCGAGCCGGCTCGCCCGCCAGCAGCTCGGGCTCGATGAGGCCTTGATCGATCA
AGGGATCGGGATTGTCAGGGATGATGGAGGGCCATCCGCCGGGACCGGCAAGGCGCCATTGCTTCGTGACGGCGCGGCGA
CTTTTCTGTCCCTGAGTTCTGCCCTGTCATTCTCGCCTCCCCTTGAAACGCGGAGAAAGCGTCCCACCACGCCGGCTCTT
GCACCCAAGGAGCCTTCACTCCTTGATACTTTGGCCGGCGATGATCGGCGTTTGCAGGCCTTTGTCCAGCGTATCCGCGC
CACTGCGGGTTTGAAACCGAAACTCCTCATCACGGGTGAAACTGGCACGGGGAAAGAAGTTTTCGCGCGTGCGATTCATG
GGGACAGGGTCCAAAAGAACGAGACGATCAGGAGCCCCATCGAGCGCCCCTTCATCCGCGTCGATTGCCGGGCGCTGTTA
AATTCTCAAGATTATCCTGCTCAAAACTCTTTCGCGCAAAACGCTCTCGCCGATCCGATCGAACGAGCGGCAGGTGGCAC
GCTCTTTCTCGATGAGATCGGTGATTTGCCGCTGTCGTTGCAAGCTTTCCTCGTGCATGCGCTGGATAATCATGCAGGCT
TGCGTGGGGAGGGGGCTTCGACAATCGCACTCATCTGCGCGACGCAACAGGATCTCGAAGCCCTGGTCACCGCGCGAACC
TTTCGCGCGGATCTTTATTACCGGCTCAAAGGGCTCCCGATCGATCTCCCGCCCTTGCGGTCGCGCGAGGACAAGAGCCT
GGTCATTGATCGGCTTGTGCGAGAGATTGCGCTGGGCCGCGATCTCTCGGCTACGGCGCGAAGCGCGATCGAGGCTTGTG
AATGGCCAGGCAATCTTCGCCAATTGCGGCAGGTTCTTGAACTGGCTTTTGCGAGTTCCCCGGCGCCATGCCTTGAAAGT
CATGATTTCGATTTGCCGTCCCGCACGGAACGGTTGGCGCCTGTCGGGACTTTGCAACAAGCAGAAAAAGACGTCATTGC
AAGGCAACTCGCCGAGGATGGTTTCGATATCGCCAAAGCTGCCAGCCATCTTGGCATGAGCCGGGCGACGCTTTACCGCC
GGATCAAGCATTTCGGGTTGGGCACGGGCCGCTGA

Upstream 100 bases:

>100_bases
CCGTTTTCAATGTTTATGATGCCGCCCCATAAAATTACCCGCGGGATATGAGCCGATCAAAGGCCGCTGCGGGCAAATCA
AGAGGGGAGGGTCCATGCCA

Downstream 100 bases:

>100_bases
TTCGTTCTCAGGCCTATCCATCGATTGAGGCGATGCCCCAGTATCGAGATCATAGATTCTCGATACGCCACTTTTTAAAC
TGTATCCACTTGCCCTCATT

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 623

Protein sequence:

>624_residues
MGSGDGRMPVAATAHAERIFTASFGGAETGDGPVGSLIIASWRRCLDRHKLDPERQAETRVLSRGELREAREPLDALLSL
STPLLDDLYRQVADLGYVVMLTDGNGITLNARAGNDERAFRKWGLWTGSVWSEGLEGTNGVGLCLTEQRPVTVHRGEHFR
SRHAGLTCTVAPLFNADGTIIGCLDISAFNQEIDSRIVGFAQRATTLAAGWIEAVCFRHAYRSCWIVSLGESIEGKALLA
FDEDRRLKGASRLARQQLGLDEALIDQGIGIVRDDGGPSAGTGKAPLLRDGAATFLSLSSALSFSPPLETRRKRPTTPAL
APKEPSLLDTLAGDDRRLQAFVQRIRATAGLKPKLLITGETGTGKEVFARAIHGDRVQKNETIRSPIERPFIRVDCRALL
NSQDYPAQNSFAQNALADPIERAAGGTLFLDEIGDLPLSLQAFLVHALDNHAGLRGEGASTIALICATQQDLEALVTART
FRADLYYRLKGLPIDLPPLRSREDKSLVIDRLVREIALGRDLSATARSAIEACEWPGNLRQLRQVLELAFASSPAPCLES
HDFDLPSRTERLAPVGTLQQAEKDVIARQLAEDGFDIAKAASHLGMSRATLYRRIKHFGLGTGR

Sequences:

>Translated_624_residues
MGSGDGRMPVAATAHAERIFTASFGGAETGDGPVGSLIIASWRRCLDRHKLDPERQAETRVLSRGELREAREPLDALLSL
STPLLDDLYRQVADLGYVVMLTDGNGITLNARAGNDERAFRKWGLWTGSVWSEGLEGTNGVGLCLTEQRPVTVHRGEHFR
SRHAGLTCTVAPLFNADGTIIGCLDISAFNQEIDSRIVGFAQRATTLAAGWIEAVCFRHAYRSCWIVSLGESIEGKALLA
FDEDRRLKGASRLARQQLGLDEALIDQGIGIVRDDGGPSAGTGKAPLLRDGAATFLSLSSALSFSPPLETRRKRPTTPAL
APKEPSLLDTLAGDDRRLQAFVQRIRATAGLKPKLLITGETGTGKEVFARAIHGDRVQKNETIRSPIERPFIRVDCRALL
NSQDYPAQNSFAQNALADPIERAAGGTLFLDEIGDLPLSLQAFLVHALDNHAGLRGEGASTIALICATQQDLEALVTART
FRADLYYRLKGLPIDLPPLRSREDKSLVIDRLVREIALGRDLSATARSAIEACEWPGNLRQLRQVLELAFASSPAPCLES
HDFDLPSRTERLAPVGTLQQAEKDVIARQLAEDGFDIAKAASHLGMSRATLYRRIKHFGLGTGR
>Mature_623_residues
GSGDGRMPVAATAHAERIFTASFGGAETGDGPVGSLIIASWRRCLDRHKLDPERQAETRVLSRGELREAREPLDALLSLS
TPLLDDLYRQVADLGYVVMLTDGNGITLNARAGNDERAFRKWGLWTGSVWSEGLEGTNGVGLCLTEQRPVTVHRGEHFRS
RHAGLTCTVAPLFNADGTIIGCLDISAFNQEIDSRIVGFAQRATTLAAGWIEAVCFRHAYRSCWIVSLGESIEGKALLAF
DEDRRLKGASRLARQQLGLDEALIDQGIGIVRDDGGPSAGTGKAPLLRDGAATFLSLSSALSFSPPLETRRKRPTTPALA
PKEPSLLDTLAGDDRRLQAFVQRIRATAGLKPKLLITGETGTGKEVFARAIHGDRVQKNETIRSPIERPFIRVDCRALLN
SQDYPAQNSFAQNALADPIERAAGGTLFLDEIGDLPLSLQAFLVHALDNHAGLRGEGASTIALICATQQDLEALVTARTF
RADLYYRLKGLPIDLPPLRSREDKSLVIDRLVREIALGRDLSATARSAIEACEWPGNLRQLRQVLELAFASSPAPCLESH
DFDLPSRTERLAPVGTLQQAEKDVIARQLAEDGFDIAKAASHLGMSRATLYRRIKHFGLGTGR

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=298, Percent_Identity=35.2348993288591, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87082117, Length=324, Percent_Identity=34.2592592592593, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789233, Length=340, Percent_Identity=33.8235294117647, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI1789087, Length=314, Percent_Identity=35.031847133758, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1786524, Length=320, Percent_Identity=32.5, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1790437, Length=319, Percent_Identity=30.7210031347962, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI87081858, Length=654, Percent_Identity=24.3119266055046, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788905, Length=351, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1787583, Length=324, Percent_Identity=27.4691358024691, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI87082152, Length=351, Percent_Identity=30.7692307692308, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081872, Length=238, Percent_Identity=34.453781512605, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1790299, Length=209, Percent_Identity=35.8851674641148, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789828, Length=252, Percent_Identity=29.3650793650794, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 67796; Mature: 67665

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSGDGRMPVAATAHAERIFTASFGGAETGDGPVGSLIIASWRRCLDRHKLDPERQAETR
CCCCCCCCCEEEHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
VLSRGELREAREPLDALLSLSTPLLDDLYRQVADLGYVVMLTDGNGITLNARAGNDERAF
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCHHHHH
RKWGLWTGSVWSEGLEGTNGVGLCLTEQRPVTVHRGEHFRSRHAGLTCTVAPLFNADGTI
HHHCCCCCHHHHHCCCCCCCCEEEEECCCCEEEECCCHHHHHCCCCEEEEEEEECCCCCE
IGCLDISAFNQEIDSRIVGFAQRATTLAAGWIEAVCFRHAYRSCWIVSLGESIEGKALLA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEE
FDEDRRLKGASRLARQQLGLDEALIDQGIGIVRDDGGPSAGTGKAPLLRDGAATFLSLSS
ECCCCHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
ALSFSPPLETRRKRPTTPALAPKEPSLLDTLAGDDRRLQAFVQRIRATAGLKPKLLITGE
HCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECC
TGTGKEVFARAIHGDRVQKNETIRSPIERPFIRVDCRALLNSQDYPAQNSFAQNALADPI
CCCCHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEEHHHHHCCCCCCCCHHHHHHHHHHHH
ERAAGGTLFLDEIGDLPLSLQAFLVHALDNHAGLRGEGASTIALICATQQDLEALVTART
HHHCCCEEEEHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHH
FRADLYYRLKGLPIDLPPLRSREDKSLVIDRLVREIALGRDLSATARSAIEACEWPGNLR
HHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHH
QLRQVLELAFASSPAPCLESHDFDLPSRTERLAPVGTLQQAEKDVIARQLAEDGFDIAKA
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
ASHLGMSRATLYRRIKHFGLGTGR
HHHCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GSGDGRMPVAATAHAERIFTASFGGAETGDGPVGSLIIASWRRCLDRHKLDPERQAETR
CCCCCCCCEEEHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
VLSRGELREAREPLDALLSLSTPLLDDLYRQVADLGYVVMLTDGNGITLNARAGNDERAF
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCHHHHH
RKWGLWTGSVWSEGLEGTNGVGLCLTEQRPVTVHRGEHFRSRHAGLTCTVAPLFNADGTI
HHHCCCCCHHHHHCCCCCCCCEEEEECCCCEEEECCCHHHHHCCCCEEEEEEEECCCCCE
IGCLDISAFNQEIDSRIVGFAQRATTLAAGWIEAVCFRHAYRSCWIVSLGESIEGKALLA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEE
FDEDRRLKGASRLARQQLGLDEALIDQGIGIVRDDGGPSAGTGKAPLLRDGAATFLSLSS
ECCCCHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
ALSFSPPLETRRKRPTTPALAPKEPSLLDTLAGDDRRLQAFVQRIRATAGLKPKLLITGE
HCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECC
TGTGKEVFARAIHGDRVQKNETIRSPIERPFIRVDCRALLNSQDYPAQNSFAQNALADPI
CCCCHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEEHHHHHCCCCCCCCHHHHHHHHHHHH
ERAAGGTLFLDEIGDLPLSLQAFLVHALDNHAGLRGEGASTIALICATQQDLEALVTART
HHHCCCEEEEHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHH
FRADLYYRLKGLPIDLPPLRSREDKSLVIDRLVREIALGRDLSATARSAIEACEWPGNLR
HHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHH
QLRQVLELAFASSPAPCLESHDFDLPSRTERLAPVGTLQQAEKDVIARQLAEDGFDIAKA
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
ASHLGMSRATLYRRIKHFGLGTGR
HHHCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]