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The map label for this gene is iorA [H]

Identifier: 182679831

GI number: 182679831

Start: 3327557

End: 3328009

Strand: Reverse

Name: iorA [H]

Synonym: Bind_2920

Alternate gene names: 182679831

Gene position: 3328009-3327557 (Counterclockwise)

Preceding gene: 182679837

Following gene: 182679830

Centisome position: 79.81

GC content: 59.6

Gene sequence:

>453_bases
ATGATCAAGCTCCAAATCAATGGGCGGGAATGGTCCTATGACGGCGACCCGACGATCCCCTTGCTCTGGGTGCTGCGTGA
TGAATTGGGCCTGACCGGCACGAAATTCGGTTGTGGCGCGGGATTATGCGGTTCTTGCACCGTTCACATTGATGGTGAGG
CGCAACGCGCCTGCACTCTGCAAGTGAGCGATGCGCAAGGTCACGAGGTCGTGACGATCGAAGGGCTCGATCCGCAGGGT
AACCACCCCGTTCAAAGGGCCTGGCGCCAGCTCAATGTCCCGCAATGCGGTTATTGCCAAGCCGGTCAGATCATGCAGGC
AGCGGCCTTTCTCGCCAAGACGCCGAATCCGACCCAAGAAGACATCCATGGCGCGATGTCCGGCAATATCTGCCGCTGTG
GCTGTTATCAGCGCATTGAAGCGGCGGTCCACCTTGCCAGCACGGGGGTCTGA

Upstream 100 bases:

>100_bases
ATTCAACTATTCCTTTGGTAAACTGAAACACGATTCTAAGTCGAATGTATAGAACGTACGTTTTAGCAATATATCAATAA
GTATAGGTGGGAGGCCTTGC

Downstream 100 bases:

>100_bases
TATGGGCTTTGTCGATAAAACTCTCGCCGATAAAAACTCCCCCCGTGGCGAGCAGCACGATCTCGGCCGCCGCGACTTTT
TGCGGAGCATTTTGGCTGCT

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MIKLQINGREWSYDGDPTIPLLWVLRDELGLTGTKFGCGAGLCGSCTVHIDGEAQRACTLQVSDAQGHEVVTIEGLDPQG
NHPVQRAWRQLNVPQCGYCQAGQIMQAAAFLAKTPNPTQEDIHGAMSGNICRCGCYQRIEAAVHLASTGV

Sequences:

>Translated_150_residues
MIKLQINGREWSYDGDPTIPLLWVLRDELGLTGTKFGCGAGLCGSCTVHIDGEAQRACTLQVSDAQGHEVVTIEGLDPQG
NHPVQRAWRQLNVPQCGYCQAGQIMQAAAFLAKTPNPTQEDIHGAMSGNICRCGCYQRIEAAVHLASTGV
>Mature_150_residues
MIKLQINGREWSYDGDPTIPLLWVLRDELGLTGTKFGCGAGLCGSCTVHIDGEAQRACTLQVSDAQGHEVVTIEGLDPQG
NHPVQRAWRQLNVPQCGYCQAGQIMQAAAFLAKTPNPTQEDIHGAMSGNICRCGCYQRIEAAVHLASTGV

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=147, Percent_Identity=36.734693877551, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=39.5061728395062, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1789232, Length=141, Percent_Identity=39.0070921985816, Blast_Score=88, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=151, Percent_Identity=39.0728476821192, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=36.1290322580645, Blast_Score=103, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=159, Percent_Identity=34.5911949685535, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17737937, Length=147, Percent_Identity=35.3741496598639, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24647201, Length=148, Percent_Identity=33.1081081081081, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24647195, Length=158, Percent_Identity=32.9113924050633, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24647197, Length=158, Percent_Identity=32.9113924050633, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24647199, Length=151, Percent_Identity=32.4503311258278, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24647193, Length=157, Percent_Identity=34.3949044585987, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16107; Mature: 16107

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
6.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLQINGREWSYDGDPTIPLLWVLRDELGLTGTKFGCGAGLCGSCTVHIDGEAQRACTL
CEEEEECCCEECCCCCCCCEEEEEEEHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEE
QVSDAQGHEVVTIEGLDPQGNHPVQRAWRQLNVPQCGYCQAGQIMQAAAFLAKTPNPTQE
EECCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHH
DIHGAMSGNICRCGCYQRIEAAVHLASTGV
HHHHHCCCCEEEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIKLQINGREWSYDGDPTIPLLWVLRDELGLTGTKFGCGAGLCGSCTVHIDGEAQRACTL
CEEEEECCCEECCCCCCCCEEEEEEEHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEE
QVSDAQGHEVVTIEGLDPQGNHPVQRAWRQLNVPQCGYCQAGQIMQAAAFLAKTPNPTQE
EECCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHH
DIHGAMSGNICRCGCYQRIEAAVHLASTGV
HHHHHCCCCEEEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]