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The map label for this gene is mdtA [H]

Identifier: 182679789

GI number: 182679789

Start: 3284263

End: 3285570

Strand: Reverse

Name: mdtA [H]

Synonym: Bind_2877

Alternate gene names: 182679789

Gene position: 3285570-3284263 (Counterclockwise)

Preceding gene: 182679790

Following gene: 182679785

Centisome position: 78.79

GC content: 57.57

Gene sequence:

>1308_bases
ATGAGCGAGGCATTCTCTAAGGTTGAAGACGCGCCGCGCAAGACGGGCGCTGCTGGGCATGAGGATTACCCTATGCCGTC
GAAAAAGATCTTCGTCGTGGTTCTTCTGCTGGTTGGCGGCGCTCTGGCCTATGGCGCCTATGGCCATTGGCGGCGCAGCG
TCGAAGCGGCTGAGACCCAGGAGAAGACGATCAATTTCGTGCCGAAGGTCCGGGTCCAGGACGTCAAGCTGCTTGATGAG
CCAGTCCGATTGAAATTGCCCGGGCAGACCGTCGCCTTCAATACGGCGTCTCTTTATGCCCGCGCCACCGGCTACATTGC
CGAACGGCATGTGGACATCGGCAGCCGCGTCAAAAAAGGTGATTTGCTCGTACGCATCGCTTCTCCCGATCTCGATCGGC
AGCTTGATCAAGCCGAGGCGCAATTGAAGCAGGTCGAGGCGGCTCTGGCGCAGGCGCAGGCACAGGTCGATCAGGCCGAG
GCCAATGTGCGTCTCGCCAATGTGACGTATTCCCGTGCGGACGCTTTGACCAAGCGCGGTTATGAAACATTGCAGACCCG
GGACAATCAGCAGGCCAATGTCTCGGTGCAGCAGGCGACATTGGAGACCGCACATGCGGGGGTCAAATTGGCTCAAGCCA
ATGTGCAGGCGCAAAAGGCGACGGTTGATCGATTGCGGACACTGACCGCCTTTGAACAGGTGGTGGCCCCATTCGATGGC
GTCATCACGGCGCGCAACGTCGAGGTTGGGGATCTTGTCAATGCCGATAATGGCAATGGCACGCCGATGTTCTCCATCAA
CCATGACGACGTTTTGCGCGTGGCGGTCAATGTTCCGCAGAGCTCGGCGATTGGGGTGACGGAAGGGCTGACCGCCGAGG
TTCAAGTGCCGCAAATGCCGCAGCGTGTATTCACCGGCAAGGTGGCGCGCAGTTCGGTGGCGTTGACTGCGTCCTCACGC
ACACTCTCGACGGAAATCGATGTCATCAATAAGGATGGTGCTTTGCGTCCAGGCCTTTTTGTCGATGTGACCTTCGCTGT
CCCGCGTACCCATCCCAATGTCGTCGTGCCCTCCGAAGCTCTCATCTTCAATCAGCATGGTTTGCATGTGGCCGTGCTGG
GTCCTGATAATCGGATTGTTCTACGCCCTGTGACGATCTATCGGGATTTTGGGCAAACTGTTGAATTAAATGATGGTTTG
GAAGGTCACGAGAAAATCGTGTTGAGTCCGCCGGCGATTCTCGCTGATGGGAGCAAGGTGGATGTCGTGCCGAATGAGAA
CGAAAAACAGGCATCTGCCACTCCGTGA

Upstream 100 bases:

>100_bases
TCGGCGGCGTCGCCGTGGCGACATGCTCCACTTTGCTCTTCGTGCCCTTTCTTTATTCGGTCCTGCGCAACGGGAAGGTC
GAACCGGTCAAGGATTATCT

Downstream 100 bases:

>100_bases
TTAAGGAATGGGTCGAGGCAACAACTCGCCCGGCTACGAGCAGACTGTTTGAGTATATGCGCTGTCATAGAGGGGTATGG
AAAGATGAAACATTATCTTT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSEAFSKVEDAPRKTGAAGHEDYPMPSKKIFVVVLLLVGGALAYGAYGHWRRSVEAAETQEKTINFVPKVRVQDVKLLDE
PVRLKLPGQTVAFNTASLYARATGYIAERHVDIGSRVKKGDLLVRIASPDLDRQLDQAEAQLKQVEAALAQAQAQVDQAE
ANVRLANVTYSRADALTKRGYETLQTRDNQQANVSVQQATLETAHAGVKLAQANVQAQKATVDRLRTLTAFEQVVAPFDG
VITARNVEVGDLVNADNGNGTPMFSINHDDVLRVAVNVPQSSAIGVTEGLTAEVQVPQMPQRVFTGKVARSSVALTASSR
TLSTEIDVINKDGALRPGLFVDVTFAVPRTHPNVVVPSEALIFNQHGLHVAVLGPDNRIVLRPVTIYRDFGQTVELNDGL
EGHEKIVLSPPAILADGSKVDVVPNENEKQASATP

Sequences:

>Translated_435_residues
MSEAFSKVEDAPRKTGAAGHEDYPMPSKKIFVVVLLLVGGALAYGAYGHWRRSVEAAETQEKTINFVPKVRVQDVKLLDE
PVRLKLPGQTVAFNTASLYARATGYIAERHVDIGSRVKKGDLLVRIASPDLDRQLDQAEAQLKQVEAALAQAQAQVDQAE
ANVRLANVTYSRADALTKRGYETLQTRDNQQANVSVQQATLETAHAGVKLAQANVQAQKATVDRLRTLTAFEQVVAPFDG
VITARNVEVGDLVNADNGNGTPMFSINHDDVLRVAVNVPQSSAIGVTEGLTAEVQVPQMPQRVFTGKVARSSVALTASSR
TLSTEIDVINKDGALRPGLFVDVTFAVPRTHPNVVVPSEALIFNQHGLHVAVLGPDNRIVLRPVTIYRDFGQTVELNDGL
EGHEKIVLSPPAILADGSKVDVVPNENEKQASATP
>Mature_434_residues
SEAFSKVEDAPRKTGAAGHEDYPMPSKKIFVVVLLLVGGALAYGAYGHWRRSVEAAETQEKTINFVPKVRVQDVKLLDEP
VRLKLPGQTVAFNTASLYARATGYIAERHVDIGSRVKKGDLLVRIASPDLDRQLDQAEAQLKQVEAALAQAQAQVDQAEA
NVRLANVTYSRADALTKRGYETLQTRDNQQANVSVQQATLETAHAGVKLAQANVQAQKATVDRLRTLTAFEQVVAPFDGV
ITARNVEVGDLVNADNGNGTPMFSINHDDVLRVAVNVPQSSAIGVTEGLTAEVQVPQMPQRVFTGKVARSSVALTASSRT
LSTEIDVINKDGALRPGLFVDVTFAVPRTHPNVVVPSEALIFNQHGLHVAVLGPDNRIVLRPVTIYRDFGQTVELNDGLE
GHEKIVLSPPAILADGSKVDVVPNENEKQASATP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=361, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081796, Length=156, Percent_Identity=33.974358974359, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789929, Length=336, Percent_Identity=23.5119047619048, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786787, Length=176, Percent_Identity=29.5454545454545, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46904; Mature: 46772

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAFSKVEDAPRKTGAAGHEDYPMPSKKIFVVVLLLVGGALAYGAYGHWRRSVEAAETQ
CCHHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EKTINFVPKVRVQDVKLLDEPVRLKLPGQTVAFNTASLYARATGYIAERHVDIGSRVKKG
HHHCCCCCCCEEECHHHCCCCEEEEECCCEEEEEHHHHHHHHHCHHHEEECCCCCCCCCC
DLLVRIASPDLDRQLDQAEAQLKQVEAALAQAQAQVDQAEANVRLANVTYSRADALTKRG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHCC
YETLQTRDNQQANVSVQQATLETAHAGVKLAQANVQAQKATVDRLRTLTAFEQVVAPFDG
CHHHHCCCCCCCCEEEHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
VITARNVEVGDLVNADNGNGTPMFSINHDDVLRVAVNVPQSSAIGVTEGLTAEVQVPQMP
EEEECCCCCCCEEECCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCC
QRVFTGKVARSSVALTASSRTLSTEIDVINKDGALRPGLFVDVTFAVPRTHPNVVVPSEA
HHHHHCHHHHCEEEEEECCCEEEEEEEEECCCCCCCCCEEEEEEEEECCCCCCEEECCCE
LIFNQHGLHVAVLGPDNRIVLRPVTIYRDFGQTVELNDGLEGHEKIVLSPPAILADGSKV
EEEECCCCEEEEECCCCEEEEEEEEEEECCCCEEEECCCCCCCCEEEECCCCEEECCCEE
DVVPNENEKQASATP
EECCCCCCCCCCCCC
>Mature Secondary Structure 
SEAFSKVEDAPRKTGAAGHEDYPMPSKKIFVVVLLLVGGALAYGAYGHWRRSVEAAETQ
CHHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EKTINFVPKVRVQDVKLLDEPVRLKLPGQTVAFNTASLYARATGYIAERHVDIGSRVKKG
HHHCCCCCCCEEECHHHCCCCEEEEECCCEEEEEHHHHHHHHHCHHHEEECCCCCCCCCC
DLLVRIASPDLDRQLDQAEAQLKQVEAALAQAQAQVDQAEANVRLANVTYSRADALTKRG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHCC
YETLQTRDNQQANVSVQQATLETAHAGVKLAQANVQAQKATVDRLRTLTAFEQVVAPFDG
CHHHHCCCCCCCCEEEHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
VITARNVEVGDLVNADNGNGTPMFSINHDDVLRVAVNVPQSSAIGVTEGLTAEVQVPQMP
EEEECCCCCCCEEECCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCC
QRVFTGKVARSSVALTASSRTLSTEIDVINKDGALRPGLFVDVTFAVPRTHPNVVVPSEA
HHHHHCHHHHCEEEEEECCCEEEEEEEEECCCCCCCCCEEEEEEEEECCCCCCEEECCCE
LIFNQHGLHVAVLGPDNRIVLRPVTIYRDFGQTVELNDGLEGHEKIVLSPPAILADGSKV
EEEECCCCEEEEECCCCEEEEEEEEEEECCCCEEEECCCCCCCCEEEECCCCEEECCCEE
DVVPNENEKQASATP
EECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]