Click here to switch to the map view.

The map label for this gene is rocD [H]

Identifier: 182679726

GI number: 182679726

Start: 3205709

End: 3206947

Strand: Reverse

Name: rocD [H]

Synonym: Bind_2814

Alternate gene names: 182679726

Gene position: 3206947-3205709 (Counterclockwise)

Preceding gene: 182679729

Following gene: 182679725

Centisome position: 76.9

GC content: 59.08

Gene sequence:

>1239_bases
TTGAGGCATGATTTCATCGATCAGGAAGAAAGATTCGGAGCGCATAATTATGCGCCCTTGCCGGTCGTTTTAAGCCATGG
GCAAGGAGCATTTCTGTTCGACTGCGACGGGCGTCGTTATCTCGATATGATGAGCGCCTATTCGGCGGCGAGTTTCGGCC
ATTTACATCCGCGCCTTGTTGGCGCACTCAAGCGTCAGCTCGAGCGTTTGGATCTCGTGTCTCGCGCCTATCATACGGAT
ACGCTCGGGCCATTTTGCGAGGATCTCGCCCGTTTGACCGGGCTCGACGCCTGCTTGCCGATGAATACGGGAGCGGAAGC
CGTCGAGACCGCGATCAAGGCGGCGCGACGTTACGGATATGATCGTCTTTCCATTCCCGAAGATCAAGCCGAGATCATTG
TCGCCGCCGGTAATTTCCACGGCCGCACGACGACGATCATCGGTTTTTCCAGCGATGCCGCGACACGACGCGGTTTCGGC
CCCTTTGCGCCTGGTTTCGTCTTGGTGCCGTTTGGCGATGCCGGAGCATTGGAGGCGGCGGTCGGTCCTCGCACGGCCGC
CGTCCTCATCGAGCCGATCCAGGGGGAAGCGGGAATCATTCTGCCTCCCCCTGGTTATCTCGCCGCCTTGCGGCGCCTCT
GCGATCGGCATGGCATTCTGTTGATTTTCGATGAGGTGCAATCAGGTTTCGGACGTACGGGCCGCACCTTCGCCTTTGAA
CATGAAGGTGCAAAACCCGATGGCCTGATCCTTGGCAAGGCGCTCGGCGGAGGTCTGTTGCCGGTCTCGGCCTTTGCCGC
GAAGCGCTCCCTGATGGATGTCTTCGATCCGGGTAGTCATGGCTCGACTTTCGGCGGTAATCCGCTCGCCATGGCGGTTG
CGCGCGAGGCCATGCATGTTTTGCAGGAAGAACACTTGGTGGAGCGAAGTGAAAAATTGGGTGGTGTGTTGTTGGATGCG
CTGCGGGCGATCGACCATCCTGCCGTTCTGGCCGTGCGGGGCAAAGGGCTTTGGGCGGGTGTCGATCTCGATCCGGCCCT
GGCCGATGCCAAAAAAGTCTGCCTGAAAATGATGGAACGGGGTGTCCTGACCAAGGAGACCCATGCGACGACGATCCGTT
TTGCGCCGCCGCTTGTCATCACCGAAGCCGATCTTCTCGAAGCCGTGGGGATTTTCCGCGCGGTCCTCGAAAGCCTGTCT
CTTCCCACCGCTGTTTCGACCTTGAGTTTTGCCAAATGA

Upstream 100 bases:

>100_bases
GGATATGCATATTATGCGGCGAAAGCTCTGATTTCCGCGCCAAAAACGCCAGCGCTCGTGCCATGATTTTCTCACAGTCC
AGAACAGCGCGAGCATCCCT

Downstream 100 bases:

>100_bases
CTTTGACTCTTTCTCGGACCCTCCCGCAGACTTCTACTCGGATGCAAACAGGTGAAGGCGCGTTCCGTCTTGCCCAGGCG
GCGGAGCCTTTCATTGTGGC

Product: ornithine aminotransferase

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MRHDFIDQEERFGAHNYAPLPVVLSHGQGAFLFDCDGRRYLDMMSAYSAASFGHLHPRLVGALKRQLERLDLVSRAYHTD
TLGPFCEDLARLTGLDACLPMNTGAEAVETAIKAARRYGYDRLSIPEDQAEIIVAAGNFHGRTTTIIGFSSDAATRRGFG
PFAPGFVLVPFGDAGALEAAVGPRTAAVLIEPIQGEAGIILPPPGYLAALRRLCDRHGILLIFDEVQSGFGRTGRTFAFE
HEGAKPDGLILGKALGGGLLPVSAFAAKRSLMDVFDPGSHGSTFGGNPLAMAVAREAMHVLQEEHLVERSEKLGGVLLDA
LRAIDHPAVLAVRGKGLWAGVDLDPALADAKKVCLKMMERGVLTKETHATTIRFAPPLVITEADLLEAVGIFRAVLESLS
LPTAVSTLSFAK

Sequences:

>Translated_412_residues
MRHDFIDQEERFGAHNYAPLPVVLSHGQGAFLFDCDGRRYLDMMSAYSAASFGHLHPRLVGALKRQLERLDLVSRAYHTD
TLGPFCEDLARLTGLDACLPMNTGAEAVETAIKAARRYGYDRLSIPEDQAEIIVAAGNFHGRTTTIIGFSSDAATRRGFG
PFAPGFVLVPFGDAGALEAAVGPRTAAVLIEPIQGEAGIILPPPGYLAALRRLCDRHGILLIFDEVQSGFGRTGRTFAFE
HEGAKPDGLILGKALGGGLLPVSAFAAKRSLMDVFDPGSHGSTFGGNPLAMAVAREAMHVLQEEHLVERSEKLGGVLLDA
LRAIDHPAVLAVRGKGLWAGVDLDPALADAKKVCLKMMERGVLTKETHATTIRFAPPLVITEADLLEAVGIFRAVLESLS
LPTAVSTLSFAK
>Mature_412_residues
MRHDFIDQEERFGAHNYAPLPVVLSHGQGAFLFDCDGRRYLDMMSAYSAASFGHLHPRLVGALKRQLERLDLVSRAYHTD
TLGPFCEDLARLTGLDACLPMNTGAEAVETAIKAARRYGYDRLSIPEDQAEIIVAAGNFHGRTTTIIGFSSDAATRRGFG
PFAPGFVLVPFGDAGALEAAVGPRTAAVLIEPIQGEAGIILPPPGYLAALRRLCDRHGILLIFDEVQSGFGRTGRTFAFE
HEGAKPDGLILGKALGGGLLPVSAFAAKRSLMDVFDPGSHGSTFGGNPLAMAVAREAMHVLQEEHLVERSEKLGGVLLDA
LRAIDHPAVLAVRGKGLWAGVDLDPALADAKKVCLKMMERGVLTKETHATTIRFAPPLVITEADLLEAVGIFRAVLESLS
LPTAVSTLSFAK

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=398, Percent_Identity=48.2412060301507, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=49.1694352159468, Blast_Score=288, Evalue=8e-78,
Organism=Homo sapiens, GI37574042, Length=408, Percent_Identity=28.1862745098039, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI13994255, Length=438, Percent_Identity=27.1689497716895, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=27.511961722488, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226442705, Length=408, Percent_Identity=26.9607843137255, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226442709, Length=373, Percent_Identity=28.1501340482574, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI188536080, Length=426, Percent_Identity=25.1173708920188, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI38679950, Length=426, Percent_Identity=25.1173708920188, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI38679946, Length=426, Percent_Identity=25.1173708920188, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1789759, Length=379, Percent_Identity=38.2585751978892, Blast_Score=237, Evalue=9e-64,
Organism=Escherichia coli, GI145693181, Length=366, Percent_Identity=38.5245901639344, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1788044, Length=384, Percent_Identity=34.1145833333333, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1787560, Length=403, Percent_Identity=34.4913151364764, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789016, Length=411, Percent_Identity=30.9002433090024, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786991, Length=333, Percent_Identity=34.5345345345345, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786349, Length=330, Percent_Identity=29.6969696969697, Blast_Score=122, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=391, Percent_Identity=45.5242966751918, Blast_Score=377, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=45.3531598513011, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI32564660, Length=431, Percent_Identity=29.9303944315545, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71981843, Length=171, Percent_Identity=43.2748538011696, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=431, Percent_Identity=29.2343387470998, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17541228, Length=425, Percent_Identity=25.4117647058824, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=46.1538461538462, Blast_Score=352, Evalue=7e-98,
Organism=Saccharomyces cerevisiae, GI6324432, Length=412, Percent_Identity=28.1553398058252, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6324386, Length=362, Percent_Identity=25.414364640884, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357415, Length=393, Percent_Identity=47.5826972010178, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI28574759, Length=437, Percent_Identity=29.0617848970252, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21356575, Length=431, Percent_Identity=28.3062645011601, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI161085790, Length=422, Percent_Identity=28.1990521327014, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281366494, Length=434, Percent_Identity=25.3456221198157, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24667139, Length=434, Percent_Identity=25.3456221198157, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24667143, Length=434, Percent_Identity=25.3456221198157, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 44054; Mature: 44054

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHDFIDQEERFGAHNYAPLPVVLSHGQGAFLFDCDGRRYLDMMSAYSAASFGHLHPRLV
CCCCCCCCHHHCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHH
GALKRQLERLDLVSRAYHTDTLGPFCEDLARLTGLDACLPMNTGAEAVETAIKAARRYGY
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
DRLSIPEDQAEIIVAAGNFHGRTTTIIGFSSDAATRRGFGPFAPGFVLVPFGDAGALEAA
CCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCEEEEECCCCCCHHHC
VGPRTAAVLIEPIQGEAGIILPPPGYLAALRRLCDRHGILLIFDEVQSGFGRTGRTFAFE
CCCCEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCEEEEE
HEGAKPDGLILGKALGGGLLPVSAFAAKRSLMDVFDPGSHGSTFGGNPLAMAVAREAMHV
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
LQEEHLVERSEKLGGVLLDALRAIDHPAVLAVRGKGLWAGVDLDPALADAKKVCLKMMER
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHC
GVLTKETHATTIRFAPPLVITEADLLEAVGIFRAVLESLSLPTAVSTLSFAK
CCCCCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure
MRHDFIDQEERFGAHNYAPLPVVLSHGQGAFLFDCDGRRYLDMMSAYSAASFGHLHPRLV
CCCCCCCCHHHCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHH
GALKRQLERLDLVSRAYHTDTLGPFCEDLARLTGLDACLPMNTGAEAVETAIKAARRYGY
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
DRLSIPEDQAEIIVAAGNFHGRTTTIIGFSSDAATRRGFGPFAPGFVLVPFGDAGALEAA
CCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCHHHCCCCCCCCCEEEEECCCCCCHHHC
VGPRTAAVLIEPIQGEAGIILPPPGYLAALRRLCDRHGILLIFDEVQSGFGRTGRTFAFE
CCCCEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCEEEEE
HEGAKPDGLILGKALGGGLLPVSAFAAKRSLMDVFDPGSHGSTFGGNPLAMAVAREAMHV
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
LQEEHLVERSEKLGGVLLDALRAIDHPAVLAVRGKGLWAGVDLDPALADAKKVCLKMMER
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHHC
GVLTKETHATTIRFAPPLVITEADLLEAVGIFRAVLESLSLPTAVSTLSFAK
CCCCCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA