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The map label for this gene is murA

Identifier: 182679635

GI number: 182679635

Start: 3098731

End: 3100026

Strand: Reverse

Name: murA

Synonym: Bind_2720

Alternate gene names: 182679635

Gene position: 3100026-3098731 (Counterclockwise)

Preceding gene: 182679636

Following gene: 182679634

Centisome position: 74.34

GC content: 60.34

Gene sequence:

>1296_bases
ATGGATCGCATTCGCATCGTGGGCGGCCGGACGCTCGAAGGCACTATCAAGATTTCAGGTGCGAAAAATGCCGCTTTGCC
CTTGATGATCGCGTCCCTTCTGACATCTGAGACGCTGACGCTTGAAAACGTCCCGGCGCTCGCCGACGTCAATATGCTGT
TGCGCATTCTCGGTCACCACGGTGTCGATTATTCGGTGAACGGCCGACGTGCCGGCGAGGAGCCGCATGCGAGCCGGGCG
ATTCATCTCACCGCCGGCACCATCGTTGATATTATGGCGCCCTATGATCTCGTTTCAAAAATGCGGGCGAGTTTCTGGGT
CATCGCGCCGCTGCTCGCGCGGATGGGAGAGGCGCGCGTTTCGTTGCCCGGCGGCTGCGCCATCGGCACGCGGCCCGTCG
ATCTCCTGCTCATGGTTTTGGAAAAATTAGGCGCGAAGATCGAGATCGAAGCGGGCTATGTGCACGCCAAGGCGCCCAAG
GGTCTGCATGGCGCCGAGATCACCTTTCCCAAAGTGACGGTTGGTGGCACGCATACGGCCTTGATGGCGGCCTCGCTGGC
GCAAGGCCATACTCTGCTCGTCAATGCGGCTCGCGAGCCAGAAATCGTCGATCTCGCCAATTGCCTTACGAAAATGGGGG
CGAAGATCAAGGGGGCAGGGCAATCGACGGTCGAAATCGAGGGCGTTGGGCGTCTTTCTGGCGCGAGCCATAAGGTGCTT
CCCGATCGGATCGAGGCGGGAACCTATGCGATCGCCGTGGCCATGGCGGGGGGTGATGTCCTGCTTGAAGGCGCTGAAGC
GGACCTTTTGCAGACGGCCCTCGATACGATCGAACAAGCGGGGGCCCGCATTTCTGTCACCAATGAGGGAATCAGGGTGA
GGCGCAACGGCGCGGGCCTTCAGCCGGTCGACGTCACGACAGCACCGTTCCCGGGCTTTCCGACCGATCTTCAAGCGCAA
TTCATGGCCCTCATGACGAAAGCCAAGGGGTCATCGACGATTACCGAGACGATTTTCGAAAATCGTTTCATGCATGTGCA
GGAATTGGCGCGGCTTGGCGCCCATATTCGCCTCGAGGGTGATGCCGCAATTGTCGAGGGTGTCGAAACACTGCAAGGCG
CGCCCGTCATGGCGACGGATCTGAGGGCTTCCGTCTCCCTCGTCATTGCGGCGCTGGCGGCGCAGGGCGAGACCATGGTC
AACCGCGTCTATCATCTCGACCGGGGTTTTGAACATTTGGAAGAGAAGCTCGGCCGTTGCGGCGCAATTATCGAGCGCAT
CTCCGGCACTGCATGA

Upstream 100 bases:

>100_bases
AAGAGTTCGAGATCAATCTTTTGAAATGAACCAGGAAAGCCGTGGGGCGGGAAACGCCCGGTTTCTCCAGCTTCAGACCA
TCAAAATCGACGGGGAATGA

Downstream 100 bases:

>100_bases
TATTTTGATATAAGGTGGCCGGTTGCCAGAGCGCTTTGGGGAGAACTGGAAAGCGTTTCGAACATTATCCTGATCGCGGT
TGCGTCTGTGGTGTGATGAC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MDRIRIVGGRTLEGTIKISGAKNAALPLMIASLLTSETLTLENVPALADVNMLLRILGHHGVDYSVNGRRAGEEPHASRA
IHLTAGTIVDIMAPYDLVSKMRASFWVIAPLLARMGEARVSLPGGCAIGTRPVDLLLMVLEKLGAKIEIEAGYVHAKAPK
GLHGAEITFPKVTVGGTHTALMAASLAQGHTLLVNAAREPEIVDLANCLTKMGAKIKGAGQSTVEIEGVGRLSGASHKVL
PDRIEAGTYAIAVAMAGGDVLLEGAEADLLQTALDTIEQAGARISVTNEGIRVRRNGAGLQPVDVTTAPFPGFPTDLQAQ
FMALMTKAKGSSTITETIFENRFMHVQELARLGAHIRLEGDAAIVEGVETLQGAPVMATDLRASVSLVIAALAAQGETMV
NRVYHLDRGFEHLEEKLGRCGAIIERISGTA

Sequences:

>Translated_431_residues
MDRIRIVGGRTLEGTIKISGAKNAALPLMIASLLTSETLTLENVPALADVNMLLRILGHHGVDYSVNGRRAGEEPHASRA
IHLTAGTIVDIMAPYDLVSKMRASFWVIAPLLARMGEARVSLPGGCAIGTRPVDLLLMVLEKLGAKIEIEAGYVHAKAPK
GLHGAEITFPKVTVGGTHTALMAASLAQGHTLLVNAAREPEIVDLANCLTKMGAKIKGAGQSTVEIEGVGRLSGASHKVL
PDRIEAGTYAIAVAMAGGDVLLEGAEADLLQTALDTIEQAGARISVTNEGIRVRRNGAGLQPVDVTTAPFPGFPTDLQAQ
FMALMTKAKGSSTITETIFENRFMHVQELARLGAHIRLEGDAAIVEGVETLQGAPVMATDLRASVSLVIAALAAQGETMV
NRVYHLDRGFEHLEEKLGRCGAIIERISGTA
>Mature_431_residues
MDRIRIVGGRTLEGTIKISGAKNAALPLMIASLLTSETLTLENVPALADVNMLLRILGHHGVDYSVNGRRAGEEPHASRA
IHLTAGTIVDIMAPYDLVSKMRASFWVIAPLLARMGEARVSLPGGCAIGTRPVDLLLMVLEKLGAKIEIEAGYVHAKAPK
GLHGAEITFPKVTVGGTHTALMAASLAQGHTLLVNAAREPEIVDLANCLTKMGAKIKGAGQSTVEIEGVGRLSGASHKVL
PDRIEAGTYAIAVAMAGGDVLLEGAEADLLQTALDTIEQAGARISVTNEGIRVRRNGAGLQPVDVTTAPFPGFPTDLQAQ
FMALMTKAKGSSTITETIFENRFMHVQELARLGAHIRLEGDAAIVEGVETLQGAPVMATDLRASVSLVIAALAAQGETMV
NRVYHLDRGFEHLEEKLGRCGAIIERISGTA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=429, Percent_Identity=49.8834498834499, Blast_Score=413, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_BEII9 (B2IJH9)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001833781.1
- GeneID:   6198750
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_2720
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45392; Mature: 45392

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRIVGGRTLEGTIKISGAKNAALPLMIASLLTSETLTLENVPALADVNMLLRILGHH
CCCEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCC
GVDYSVNGRRAGEEPHASRAIHLTAGTIVDIMAPYDLVSKMRASFWVIAPLLARMGEARV
CCCEEECCCCCCCCCCCCCEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEE
SLPGGCAIGTRPVDLLLMVLEKLGAKIEIEAGYVHAKAPKGLHGAEITFPKVTVGGTHTA
ECCCCCCCCCCHHHHHHHHHHHHCCEEEEEECEEEECCCCCCCCCEEECCEEEECCCHHH
LMAASLAQGHTLLVNAAREPEIVDLANCLTKMGAKIKGAGQSTVEIEGVGRLSGASHKVL
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCCCCCCC
PDRIEAGTYAIAVAMAGGDVLLEGAEADLLQTALDTIEQAGARISVTNEGIRVRRNGAGL
CHHHCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCC
QPVDVTTAPFPGFPTDLQAQFMALMTKAKGSSTITETIFENRFMHVQELARLGAHIRLEG
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECC
DAAIVEGVETLQGAPVMATDLRASVSLVIAALAAQGETMVNRVYHLDRGFEHLEEKLGRC
CHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHH
GAIIERISGTA
HHHHHHHCCCC
>Mature Secondary Structure
MDRIRIVGGRTLEGTIKISGAKNAALPLMIASLLTSETLTLENVPALADVNMLLRILGHH
CCCEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCC
GVDYSVNGRRAGEEPHASRAIHLTAGTIVDIMAPYDLVSKMRASFWVIAPLLARMGEARV
CCCEEECCCCCCCCCCCCCEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEE
SLPGGCAIGTRPVDLLLMVLEKLGAKIEIEAGYVHAKAPKGLHGAEITFPKVTVGGTHTA
ECCCCCCCCCCHHHHHHHHHHHHCCEEEEEECEEEECCCCCCCCCEEECCEEEECCCHHH
LMAASLAQGHTLLVNAAREPEIVDLANCLTKMGAKIKGAGQSTVEIEGVGRLSGASHKVL
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCCCCCCC
PDRIEAGTYAIAVAMAGGDVLLEGAEADLLQTALDTIEQAGARISVTNEGIRVRRNGAGL
CHHHCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCC
QPVDVTTAPFPGFPTDLQAQFMALMTKAKGSSTITETIFENRFMHVQELARLGAHIRLEG
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECC
DAAIVEGVETLQGAPVMATDLRASVSLVIAALAAQGETMVNRVYHLDRGFEHLEEKLGRC
CHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHH
GAIIERISGTA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA