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The map label for this gene is yyaJ [H]

Identifier: 182679515

GI number: 182679515

Start: 2940481

End: 2941908

Strand: Reverse

Name: yyaJ [H]

Synonym: Bind_2576

Alternate gene names: 182679515

Gene position: 2941908-2940481 (Counterclockwise)

Preceding gene: 182679520

Following gene: 182679513

Centisome position: 70.55

GC content: 57.28

Gene sequence:

>1428_bases
GTGGCTGAACAGTTTGCGGCCGATCCGGCAGGTCGTATTGGGCGTCGGATCGACGCACTACCGATGTCGCGCCGGTTGTG
GACCTGGGTGTTTCTGATATCTGTCGGCGGGCTTTTCGAAATCTATGATATGGCGCTAACCGCGCCGCTGTCCGCGGCGC
TTGTGGCTGCGCACATCTTTCACCCTGGCGAAACCGGTCTATTCGGGCTGGCCGACCAGGCGACCTTTGTCTTTGCGACT
TTCTCGGGTTTATATATTGGCGTGCTCGCCTTTTCGGCTTTCGGTGATCGGCTCGGCCGCCGCTCTGTCTTCGCGATATC
GCTGATCTGGTATGCCATTGCCACACTTGTGATGGGCCTGCAGAACTCAGTGATCCCAATCTGTCTGTGGCGCTTTCTGG
CAGGTGTGGGGCTTGGCGCGGAAGCAGTCGCGATCGACTGCTTCCTTGTGGAACTCGTGCCATCCCGCATACGAGGGAGA
GCTTTTGCGATCTCCATGGGCATCCAGTATTGCGGAATACCGTTAGCCGCCTTCCTCGCTGTTTTTCTCGTCGGCCACGC
ACCATTGGGTATCGATGGTTGGCGATGGCTGACCTTCATGCCAGTGATCGGCGCGATCGGCTTCTGGGATGCACGTCGGC
GTTTACCTGAATCTCCACGATGGCTGGCGCAAAAAGGCCGCGTGGAAGAGGCGGCCCGTGTGGTCGATTTGCTGGATGAT
GGTTCTGGCCTTATCGTTAGTCATTCAGGCCTCAAGAGAAAACCGCGCGTCGTTTTTGTTTCACGGCATCATGTGGTGCA
CATGGCCTGGATGATGCTGGTCTACTTCAACCTGCAGAACATCGCCTTTTATGGCTTCGGCAGCTGGCTCCCGACCTTGA
TCCAGTCGCAAGGTGCCAATCTGAAATCGAGTTTGTTCTACTCTGCAGGCGTGGCATTGGCGGCACCGACCGCGCCACTG
CTGCTTAGCTTGATCAGTGACAGATTCGAACGCAAGCATCTGATCATCGTTAGCGGCTTGTTTGCTGTCGTCGCGGGTCT
TAGTTTTGCCTACGCCGATGCCCCACTTGGCTGGGTTGTGTTCGGCATTGGACTGACGCTGAGCAATTCAGTGTTGTCGG
TCAACAGTCACAACTACCTCAGCGAACTGTTCCCGACTCGCATCCGGGCGCGAATGGTCGGCTTCCTCTACTCGTTCACC
CGGCTCTCCGCTGCCGTCAGCGGCTACATCATCGCCTATGTGCTGGCGGAAACCGGTGTAAAGGGAGTCTTCGCGCTGAT
CAGTACGCTCATGATCGTGGCAATATCCGTCATCGGGCTGTTCGGACCTCGGACGTCTGGCGTGACTTTCGACGAGGCCG
CTTCCGATGATCAGATTCCCGTCGGAACGGGCAATTCGGAGACCGACAAAAAACTGGGGAGTCGCTGA

Upstream 100 bases:

>100_bases
CGCAGAACATGATGAATTCAATCAAGATTGATGCTTTACGCTTCTCGAAATATGTTCCGGCGAACAATGGCATTGACCGC
GAGCCAATGGGAGGAAGACT

Downstream 100 bases:

>100_bases
GGGAAACTCCACTGTCGGACGGTCGATAACCGGGTTCTGTTCCAATTTGCGTGCTTGATTGGCTTGGGAGAGCCGAGCCC
CCATATATAGGGCATGCGGA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MAEQFAADPAGRIGRRIDALPMSRRLWTWVFLISVGGLFEIYDMALTAPLSAALVAAHIFHPGETGLFGLADQATFVFAT
FSGLYIGVLAFSAFGDRLGRRSVFAISLIWYAIATLVMGLQNSVIPICLWRFLAGVGLGAEAVAIDCFLVELVPSRIRGR
AFAISMGIQYCGIPLAAFLAVFLVGHAPLGIDGWRWLTFMPVIGAIGFWDARRRLPESPRWLAQKGRVEEAARVVDLLDD
GSGLIVSHSGLKRKPRVVFVSRHHVVHMAWMMLVYFNLQNIAFYGFGSWLPTLIQSQGANLKSSLFYSAGVALAAPTAPL
LLSLISDRFERKHLIIVSGLFAVVAGLSFAYADAPLGWVVFGIGLTLSNSVLSVNSHNYLSELFPTRIRARMVGFLYSFT
RLSAAVSGYIIAYVLAETGVKGVFALISTLMIVAISVIGLFGPRTSGVTFDEAASDDQIPVGTGNSETDKKLGSR

Sequences:

>Translated_475_residues
MAEQFAADPAGRIGRRIDALPMSRRLWTWVFLISVGGLFEIYDMALTAPLSAALVAAHIFHPGETGLFGLADQATFVFAT
FSGLYIGVLAFSAFGDRLGRRSVFAISLIWYAIATLVMGLQNSVIPICLWRFLAGVGLGAEAVAIDCFLVELVPSRIRGR
AFAISMGIQYCGIPLAAFLAVFLVGHAPLGIDGWRWLTFMPVIGAIGFWDARRRLPESPRWLAQKGRVEEAARVVDLLDD
GSGLIVSHSGLKRKPRVVFVSRHHVVHMAWMMLVYFNLQNIAFYGFGSWLPTLIQSQGANLKSSLFYSAGVALAAPTAPL
LLSLISDRFERKHLIIVSGLFAVVAGLSFAYADAPLGWVVFGIGLTLSNSVLSVNSHNYLSELFPTRIRARMVGFLYSFT
RLSAAVSGYIIAYVLAETGVKGVFALISTLMIVAISVIGLFGPRTSGVTFDEAASDDQIPVGTGNSETDKKLGSR
>Mature_474_residues
AEQFAADPAGRIGRRIDALPMSRRLWTWVFLISVGGLFEIYDMALTAPLSAALVAAHIFHPGETGLFGLADQATFVFATF
SGLYIGVLAFSAFGDRLGRRSVFAISLIWYAIATLVMGLQNSVIPICLWRFLAGVGLGAEAVAIDCFLVELVPSRIRGRA
FAISMGIQYCGIPLAAFLAVFLVGHAPLGIDGWRWLTFMPVIGAIGFWDARRRLPESPRWLAQKGRVEEAARVVDLLDDG
SGLIVSHSGLKRKPRVVFVSRHHVVHMAWMMLVYFNLQNIAFYGFGSWLPTLIQSQGANLKSSLFYSAGVALAAPTAPLL
LSLISDRFERKHLIIVSGLFAVVAGLSFAYADAPLGWVVFGIGLTLSNSVLSVNSHNYLSELFPTRIRARMVGFLYSFTR
LSAAVSGYIIAYVLAETGVKGVFALISTLMIVAISVIGLFGPRTSGVTFDEAASDDQIPVGTGNSETDKKLGSR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI302148518, Length=345, Percent_Identity=22.0289855072464, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788074, Length=463, Percent_Identity=27.645788336933, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788068, Length=472, Percent_Identity=25.635593220339, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI87082159, Length=400, Percent_Identity=26.75, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786229, Length=407, Percent_Identity=26.7813267813268, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790550, Length=451, Percent_Identity=24.390243902439, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790463, Length=414, Percent_Identity=24.6376811594203, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25145172, Length=451, Percent_Identity=23.5033259423503, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320595, Length=217, Percent_Identity=29.9539170506912, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922616, Length=408, Percent_Identity=23.2843137254902, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 51434; Mature: 51303

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQFAADPAGRIGRRIDALPMSRRLWTWVFLISVGGLFEIYDMALTAPLSAALVAAHIF
CCCCCCCCCHHHHHCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
HPGETGLFGLADQATFVFATFSGLYIGVLAFSAFGDRLGRRSVFAISLIWYAIATLVMGL
CCCCCCCEECCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QNSVIPICLWRFLAGVGLGAEAVAIDCFLVELVPSRIRGRAFAISMGIQYCGIPLAAFLA
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCHHHHHHH
VFLVGHAPLGIDGWRWLTFMPVIGAIGFWDARRRLPESPRWLAQKGRVEEAARVVDLLDD
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHCCCHHHHHHHHHHHCC
GSGLIVSHSGLKRKPRVVFVSRHHVVHMAWMMLVYFNLQNIAFYGFGSWLPTLIQSQGAN
CCCEEEECCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCC
LKSSLFYSAGVALAAPTAPLLLSLISDRFERKHLIIVSGLFAVVAGLSFAYADAPLGWVV
HHHHHHHHCCCHHCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHH
FGIGLTLSNSVLSVNSHNYLSELFPTRIRARMVGFLYSFTRLSAAVSGYIIAYVLAETGV
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KGVFALISTLMIVAISVIGLFGPRTSGVTFDEAASDDQIPVGTGNSETDKKLGSR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
AEQFAADPAGRIGRRIDALPMSRRLWTWVFLISVGGLFEIYDMALTAPLSAALVAAHIF
CCCCCCCCHHHHHCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
HPGETGLFGLADQATFVFATFSGLYIGVLAFSAFGDRLGRRSVFAISLIWYAIATLVMGL
CCCCCCCEECCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QNSVIPICLWRFLAGVGLGAEAVAIDCFLVELVPSRIRGRAFAISMGIQYCGIPLAAFLA
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCHHHHHHH
VFLVGHAPLGIDGWRWLTFMPVIGAIGFWDARRRLPESPRWLAQKGRVEEAARVVDLLDD
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHCCCHHHHHHHHHHHCC
GSGLIVSHSGLKRKPRVVFVSRHHVVHMAWMMLVYFNLQNIAFYGFGSWLPTLIQSQGAN
CCCEEEECCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCC
LKSSLFYSAGVALAAPTAPLLLSLISDRFERKHLIIVSGLFAVVAGLSFAYADAPLGWVV
HHHHHHHHCCCHHCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHH
FGIGLTLSNSVLSVNSHNYLSELFPTRIRARMVGFLYSFTRLSAAVSGYIIAYVLAETGV
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KGVFALISTLMIVAISVIGLFGPRTSGVTFDEAASDDQIPVGTGNSETDKKLGSR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]