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The map label for this gene is nuoH [H]

Identifier: 182679345

GI number: 182679345

Start: 2731596

End: 2732624

Strand: Reverse

Name: nuoH [H]

Synonym: Bind_2391

Alternate gene names: 182679345

Gene position: 2732624-2731596 (Counterclockwise)

Preceding gene: 182679346

Following gene: 182679344

Centisome position: 65.53

GC content: 56.75

Gene sequence:

>1029_bases
ATGAGCGATACTAGCTGGGTGCTTCCTTTCCTCCTGATGATCGTCAAGAGCCTCGTGCTCTTGGTGGTCCTCCTCGTCTT
TATCGCTTACGTGCTTTACGCCGACCGGAAGATTTGGGCGGCGGTGCAATTGCGGCGCGGACCCAATGTCGTCGGCCCCT
TCGGGCTCTTCCAGAGCTTCGCCGACATGCTGAAATTCGTGTTCAAGGAACCGGTAATCCCGGATGGCGCGAATAAGGGC
ATTTTCCTTCTTGCCCCCTTCGTCATGGGCATGTTGTCACTGGCTGCCTGGGCGGTCATTCCGTTAAGCGATGGCTGGGC
GATCGCCAATCTGAATGTCGGCGTTCTTTATATTTTCGCGATTTCCTCGCTCAGCGTTTATGGCGTCATCATGGGCGGCT
GGGCATCGAATTCGAAATATCCTTTCCTCTCGGCCCTGCGCTCAGCGGCGCAGATGGTTTCCTATGAGGTTTCGATCGGC
TTCGTCATTGTGACGGTGCTGCTCTGTGCCGGCTCGCTCAATCTCAATGACATCGTGGTGGCGCAAGATACCAAGTTCGG
CATTCTGGGCTGGTATTGGATTCCTTTGTTCCCGATGTTCGTCATCTTCTTCATCTCGGCGCTTGCCGAGACCAACCGCC
CGCCTTTCGATCTCGTCGAGGCCGAATCGGAGCTCGTCGCCGGCTTCATGGTCGAGTATTCCTCGACCCCCTACATGCTG
TTCATGCTTGCCGAATATGTGGCGATCATGACCATGTGCGCCTTGATGACGATCATGTTCTTCGGCGGCTGGCTGTCACC
CATTCCCTTCCCACCCTTTACCTGGGTGCCGGGCGTCATCTGGTTCACGCTCAAGGCCTCGCTGTTCTTCTTCATGTTCG
CGATGGTGAAAGCCTTCGTGCCGCGCTACCGCTACGATCAATTGATGCGGCTCGGCTGGAAAGTGTTTTTGCCGATCTCA
CTGTTCATGGTCGTTCTGGTCGCCGGCGTCTTGCACGCTACCGGCTGGGGCGCGGGCATGGGGCAATAG

Upstream 100 bases:

>100_bases
CGATCGCCCGCGCTTCCGGCGTGATGGCTGAATGCGCGGCCCTGGCGCAGGGCCTCGCGCGCCAGGCGGCCGAATAAAGT
AAACTCAAGGTGTGTTGGCG

Downstream 100 bases:

>100_bases
AGCCACGGAAAAGAACATGCGCCGCCACTTTCGGGTGTAGGGCACATGCTTCGGCAAGGAAACGATATGAGACTCGATTC
TGCCGCTAAGGCGCTTTTTC

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSDTSWVLPFLLMIVKSLVLLVVLLVFIAYVLYADRKIWAAVQLRRGPNVVGPFGLFQSFADMLKFVFKEPVIPDGANKG
IFLLAPFVMGMLSLAAWAVIPLSDGWAIANLNVGVLYIFAISSLSVYGVIMGGWASNSKYPFLSALRSAAQMVSYEVSIG
FVIVTVLLCAGSLNLNDIVVAQDTKFGILGWYWIPLFPMFVIFFISALAETNRPPFDLVEAESELVAGFMVEYSSTPYML
FMLAEYVAIMTMCALMTIMFFGGWLSPIPFPPFTWVPGVIWFTLKASLFFFMFAMVKAFVPRYRYDQLMRLGWKVFLPIS
LFMVVLVAGVLHATGWGAGMGQ

Sequences:

>Translated_342_residues
MSDTSWVLPFLLMIVKSLVLLVVLLVFIAYVLYADRKIWAAVQLRRGPNVVGPFGLFQSFADMLKFVFKEPVIPDGANKG
IFLLAPFVMGMLSLAAWAVIPLSDGWAIANLNVGVLYIFAISSLSVYGVIMGGWASNSKYPFLSALRSAAQMVSYEVSIG
FVIVTVLLCAGSLNLNDIVVAQDTKFGILGWYWIPLFPMFVIFFISALAETNRPPFDLVEAESELVAGFMVEYSSTPYML
FMLAEYVAIMTMCALMTIMFFGGWLSPIPFPPFTWVPGVIWFTLKASLFFFMFAMVKAFVPRYRYDQLMRLGWKVFLPIS
LFMVVLVAGVLHATGWGAGMGQ
>Mature_341_residues
SDTSWVLPFLLMIVKSLVLLVVLLVFIAYVLYADRKIWAAVQLRRGPNVVGPFGLFQSFADMLKFVFKEPVIPDGANKGI
FLLAPFVMGMLSLAAWAVIPLSDGWAIANLNVGVLYIFAISSLSVYGVIMGGWASNSKYPFLSALRSAAQMVSYEVSIGF
VIVTVLLCAGSLNLNDIVVAQDTKFGILGWYWIPLFPMFVIFFISALAETNRPPFDLVEAESELVAGFMVEYSSTPYMLF
MLAEYVAIMTMCALMTIMFFGGWLSPIPFPPFTWVPGVIWFTLKASLFFFMFAMVKAFVPRYRYDQLMRLGWKVFLPISL
FMVVLVAGVLHATGWGAGMGQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=297, Percent_Identity=41.4141414141414, Blast_Score=229, Evalue=2e-60,
Organism=Escherichia coli, GI1788618, Length=331, Percent_Identity=41.9939577039275, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1789077, Length=211, Percent_Identity=28.9099526066351, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 38048; Mature: 37917

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTSWVLPFLLMIVKSLVLLVVLLVFIAYVLYADRKIWAAVQLRRGPNVVGPFGLFQSF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHH
ADMLKFVFKEPVIPDGANKGIFLLAPFVMGMLSLAAWAVIPLSDGWAIANLNVGVLYIFA
HHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHEEECCCCEEEEECCHHHHHHHH
ISSLSVYGVIMGGWASNSKYPFLSALRSAAQMVSYEVSIGFVIVTVLLCAGSLNLNDIVV
HHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
AQDTKFGILGWYWIPLFPMFVIFFISALAETNRPPFDLVEAESELVAGFMVEYSSTPYML
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
FMLAEYVAIMTMCALMTIMFFGGWLSPIPFPPFTWVPGVIWFTLKASLFFFMFAMVKAFV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PRYRYDQLMRLGWKVFLPISLFMVVLVAGVLHATGWGAGMGQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDTSWVLPFLLMIVKSLVLLVVLLVFIAYVLYADRKIWAAVQLRRGPNVVGPFGLFQSF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHH
ADMLKFVFKEPVIPDGANKGIFLLAPFVMGMLSLAAWAVIPLSDGWAIANLNVGVLYIFA
HHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHEEECCCCEEEEECCHHHHHHHH
ISSLSVYGVIMGGWASNSKYPFLSALRSAAQMVSYEVSIGFVIVTVLLCAGSLNLNDIVV
HHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
AQDTKFGILGWYWIPLFPMFVIFFISALAETNRPPFDLVEAESELVAGFMVEYSSTPYML
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
FMLAEYVAIMTMCALMTIMFFGGWLSPIPFPPFTWVPGVIWFTLKASLFFFMFAMVKAFV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PRYRYDQLMRLGWKVFLPISLFMVVLVAGVLHATGWGAGMGQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]